Chinese medicine suppository for treating colitis and its preparing method

A technology for colitis and suppository, which is applied in the field of traditional Chinese medicine suppositories for treating colitis and its preparation, can solve the problems of inconvenient treatment methods, affecting patient compliance and the like

Active Publication Date: 2007-01-24
青岛灵鹿制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above methods have a certain curative effect, the cure rate needs to be further improved, and the treatment method is very inconvenient, which affects the patient's compliance.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Take the following raw materials by weight:

[0052] Astragalus 550g Sanqi 80g Frankincense 200g

[0053] Gallnut 200g, white scorpion 650g, white and 200g

[0054] Accessories 1000g

[0055] The above-mentioned crude drug is prepared according to the following method:

[0056] a) Gallnut, frankincense, baiji and panax notoginseng are made into fine powder.

[0057] b) Decoct the two flavors of Astragalus and Radix Sinensis with water twice, add 11 times the amount of water for the first time, and decoct for 1.5 hours; add 8 times the amount of water for the second time, and decoct for 1.5 hours; combine the decoctions, filter, The filtrate is concentrated to a clear paste with a relative density of 1.15-1.20 (80°C).

[0058] c) Mix the obtained fine powder and clear paste, dry below 80°C, and pulverize to prepare paste powder.

[0059] d) heating and melting the mixed fatty acid glycerides, adding the active ingredient, and mixing well to make a suppository.

[0...

Embodiment 2

[0062] Astragalus 600g Sanqi 85g Frankincense 190g

[0063] Gallnut 220g, white scorpion 650g, white and 195g

[0064] Accessories 900g

[0065] The above-mentioned crude drug is prepared according to the following method:

[0066] a) Make fine powder of gallnut, frankincense, baiji, sanqi and four flavors.

[0067] b) Decoct the two flavors of Radix Astragali and Radix Sinensis with water twice, combine the two decoctions, filter, concentrate the filtrate, and spray dry to obtain dry ointment powder.

[0068] c) heating and melting cocoa butter, adding fine powder and dry ointment powder, and fully mixing to make the suppository of the present invention.

[0069] According to clinical trials, rectal administration of 1 capsule each time, 2 times a day, for the treatment of colitis, 10 days as a course of treatment, observation of 1-4 courses of treatment, the total effective rate is 96%.

Embodiment 3

[0071] Take the following raw materials by weight:

[0072] Astragalus 650g Sanqi 75g Frankincense 210g

[0073] Gallnut 200g, white scorpion 700g, white and 200g

[0074] Accessories 2000g

[0075] The above-mentioned crude drug is prepared according to the following method:

[0076] a) Gallnut, frankincense, baiji and panax notoginseng are made into fine powder.

[0077] b) Decoct the two flavors of Astragalus and Radix Sinensis with water twice, add 11 times the amount of water for the first time, and decoct for 1.5 hours; add 8 times the amount of water for the second time, and decoct for 1.5 hours; combine the decoctions, filter, The filtrate is concentrated to a clear paste with a relative density of 1.15-1.20 (80°C).

[0078] c) Mix the obtained fine powder and clear paste, dry below 80°C, and pulverize to prepare paste powder.

[0079] d) Heat and melt the polyethylene glycol 4000, add the active ingredient, mix well, and make a suppository.

[0080] According to...

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PUM

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Abstract

The present invention is a kind of Chinese medicine suppository for treating colitis and its preparation process, and belongs to the field of medicine technology. The Chinese medicine suppository is prepared with astragalus root, notoginseng, frankincense, gallnut, Japanese ampelopsis and bletilla tuber in certain weight proportion, and through grinding gallnut, frankincense, bletilla tuber and notoginseng into fine powder; twice decocting astragalus root and Japanese ampelopsis, filtering the decoction, drying and crushing; mixing with supplementary material and the fine powder; and forming suppository. The Chinese medicine suppository has high curative effect on colitis, no toxicity and taking convenience.

Description

technical field [0001] The invention relates to a traditional Chinese medicine suppository for treating colitis and a preparation method thereof, belonging to the technical field of medicines. technical background [0002] Chronic ulcerative colitis is a chronic inflammation of the colon of unknown cause, also known as chronic nonspecific ulcerative colitis, idiopathic colitis. Its pathogenesis may be related to factors such as immunity, heredity, infection, mental factors, lysozyme, and allergies. Traditional Chinese medicine believes that this disease is mostly due to heat, cold and dampness or emotional internal injury, improper diet, resulting in stagnation of qi in the viscera, stagnation of qi and blood, stagnation of cold and dampness, spleen deficiency and excess dampness, spleen and kidney yang deficiency, etc., which leads to inability to transport and transform , Dampness comes from heat, which belongs to the category of dysentery, diarrhea, and intestinal retent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/02A61P1/00A61K35/64
Inventor 张为胜李诗标梅笑玲张昕张生
Owner 青岛灵鹿制药有限公司
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