Total saponin of American ginseng and injection liquid thereof

Abstract

An American ginseng saponin and its injection is prepared from the root, stem and leaf of American ginseng through cutting short, immersing in warm purified water, cyclic counter-current ultrasonic extracting, concentrating, depositing in alcohol, cold storage, filtering, evaporating for recovering alcohol, filtering, purifying by macroreticular resin column, analyzing by flushing with purified water, decoloring, vacuum recovery to obtain concentrated liquid, spray drying to obtain saponin, and dissolving it in the water for injection to obtain injection.

Description

technical field [0001] The invention relates to a preparation method of an extract, in particular to a preparation method of extracting total saponins from American ginseng stems and leaves. Background technique [0002] American ginseng (panax quinguefolium Lima.) and American ginseng stems and leaves contain a variety of identical ginsenosides. Studies have shown that the total saponins of American ginseng stems and leaves have significant effects on experimental myocardial infarction and isoproterenol-induced myocardial ischemia in rats. Protective effect; it can increase the ability of the myocardium to tolerate hypoxia; it can obviously increase the blood flow of the animal myocardium and reduce the coronary artery resistance and other physiological activities. It is a traditional Chinese medicine. The American ginseng for injection and the refined total saponins from the stems and leaves of American ginseng made with American ginseng and American ginseng stems and leav...

AI Technical Summary

Problems solved by technology

[0003] At present, because there is no high-efficiency filtration process in the production of American ginseng and total saponins from American ginseng stems and leaves, and no very effective method is used to precipitate impurities, there is no pH adjustment when recovering ethanol, and there is no further decolorization after passing through the resin column, so The total saponin content of the produced American ginseng and the total saponins of American ginseng stems and leaves is low, the total saponin content is only 50%-75%, and the amount of impurities contained is high; the previous preparation process still has the use of organic solvents in the extraction process, resulting in cost High, industrialized production is highly dangerous, not conducive to industrialized production