Medicine composition for treating cardiovascular and cerebrovascular diseases caused by qi stagnation blood stasis, preparation method and application thereof

A technology for cardiovascular and cerebrovascular diseases, qi stagnation and blood stasis, applied in cardiovascular system diseases, drug combinations, medical formulas, etc. Viscosity, the effect of treating coronary heart disease

Inactive Publication Date: 2010-09-08
HEBEI ZHAOKANG PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. The intersection angle between the artery and the aorta is almost at right angles, and the proximal end and the proximal end of the main branch are subjected to a large impact force of the blood flow, so the intima is easily damaged

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take 2500 g of purple salvia and pulverize it into coarse powder, add 15 kg of 95% ethanol to reflux for 1.5 hours, and filter; add 4 times the weight of the filter residue to 50% ethanol for reflux for 1 hour, filter; combine the filtrate, recover the ethanol to obtain ethanol extraction liquid.

[0031] Add 8 times the weight of the filter residue to the filter residue and decoct for 2 hours, filter, combine the ethanol extract and the decoction, and concentrate to a thick paste with a relative density of about 1.35 (50°C); take another 10 grams of panax notoginseng saponins. Add the powder to the extract, mix well, dry, pulverize into fine powder (100 mesh), add an appropriate amount of starch, granulate, and compress to obtain tablets.

Embodiment 2

[0033] Take 125 g of purple salvia and pulverize it into coarse powder, add 2000 g of ethanol for reflux extraction for 2 hours, and filter; add 5 times the weight of the filter residue to 49.5% dilute ethanol for reflux extraction for 1 hour and filter; combine the filtrate and recover the ethanol to obtain an ethanol extract. Add 10 times the weight of the filter residue to the filter residue and decoct for 3 hours, filter, combine the ethanol extract and the decoction, and concentrate to a thick paste with a relative density of about 1.35 (50°C); take another 50 grams of panax notoginseng saponins. Add the powder to the extract, mix well, dry, pulverize into a fine powder (100 mesh), add 344g vegetable oil, 6g beeswax, mix well, pass through colloid mill 3 times, prepare with a gelatin:glycerin:water 100:35:95 formula The rubber skin is pressed into a soft capsule.

Embodiment 3

[0035] Take 625 grams of purple salvia and pulverize it into coarse powder, add 6 times the weight of salvia miltiorrhiza, and extract it under reflux for 1.5 hours and filter; add 4 times the weight of the filter residue to 50.5% dilute ethanol for reflux extraction for 1 hour and filter; combine the filtrate and recover the ethanol to obtain Ethanol extract. The filter residue is decocted for 2 hours with 12 times the weight of the filter residue, filtered, and the ethanol extract and the decoction are combined and concentrated to a thick paste with a relative density of about 1.35 (50°C); another 50 grams of panax notoginseng saponins Add the powder to the extract, mix well, dry, pulverize into a fine powder (100 mesh), add an appropriate amount of microcrystalline cellulose, granulate, dry and encapsulate it.

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PUM

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Abstract

The invention relates to a medicinal composition for improving blood circulation and relieving stasis, wherein the composition is prepared from the following raw materials (by weight portion): panax notoginseng saponins 10-200 parts, red sage root 125-2500 parts, the invention also relates to the process for preparing the composition and use thereof.

Description

Technical field [0001] The invention relates to a medicinal composition for treating cardiovascular and cerebrovascular diseases caused by qi stagnation and blood stasis and a preparation method thereof. Specifically, it relates to a traditional Chinese medicine composition composed of panax notoginseng saponins and purple salvia, belonging to the field of traditional Chinese medicine. Background technique [0002] Coronary heart disease angina pectoris is a heart disease caused by myocardial ischemia and hypoxia caused by coronary atherosclerosis that narrows or blocks the lumen. At present, it is believed that coronary arteries are prone to atherosclerosis, which may be: 1. The blood supply of the arterial intima and part of the media is directly supplied by the lumen, and oxygen and nutrients in the blood penetrate directly into the intima and media. And because lipids are also easy to penetrate. 2. The intersection angle between the artery and the aorta is almost at right an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61K36/258A61K9/48A61K9/20A61P9/10
Inventor 兰玉岐
Owner HEBEI ZHAOKANG PHARMACY
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