HCV RNA having novel sequence

A hepatitis C virus and gene technology, applied in the direction of viral peptide, virus/phage, recombinant DNA technology, etc., can solve the problem that the hypothesis cannot be verified, and it is not used to prove the HCV infection and proliferation model.
CN1973038AInactive Publication Date: 2007-05-30ADVANCED LIFE SCI INST
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ADVANCED LIFE SCI INST
Publication Date
2007-05-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

A truncated form of hepatitis C virus gene obtained by deleting a portion of a region of a gene encoding NS2 protein from the core protein of hepatitis C virus while sustaining its translation frame. In particular, a gene as described above wherein the above-described portion of a region of the gene is located in a region encoding E1 protein and E2 protein.
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Description

Technical field

[0001] The present invention relates to the genome of chronic hepatitis C virus (hereinafter referred to as HCV). Background technique

[0002] Hepatitis C virus (HCV) is the cause of chronic hepatitis C. According to statistics from the World Health Organization (WHO), there are 170 million infected people worldwide. HCV is different from other viral hepatitis in that it only causes relatively mild symptoms at the initial stage of infection, but the chronicity of the infected person is high, and after a certain period of asymptomatic period, chronic hepatitis develops. And as the infection progresses for a long time, the symptoms further worsen, transforming into cirrhosis of the liver, leading to a high frequency of liver cancer. 95% of liver cancers are related to hepatitis virus, and most of them (80%) are caused by HCV infection.

[0003] HCV is infected through blood, blood components, and a few bodily fluid components. The HCV test method has been introduce...

Claims

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