Synthesis of melamine analog compounds
A compound and aminocarboxylate technology, applied in the field of aminocarboxylate compounds and their preparation, can solve the problems of low synthesis yield, toxic production raw materials, difficult conditions to control, etc., and achieve the effects of improving the preservation rate and prolonging the preservation period
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Embodiment 1
[0042] 2,4,6-Triamino-1,3,5-triazine-N,N,N',N',N",N"-hexaacetic acid (melamine hexaacetic acid) with 41.6g of monochloroacetic acid and 160mL of distilled water Add it to a 500mL four-necked flask, and start stirring to dissolve it completely. Keep stirring, and add 23.3g of anhydrous sodium carbonate to the monochloroacetic acid solution under a circulating tap water bath. During this process, control the reaction temperature not to exceed 60°C. After adding the anhydrous sodium carbonate, continue stirring for 15 minutes and adjust the pH= 5-10. After heating the sodium chloroacetate solution to 90°C with a water bath, add 8.4g (0.067mol) of melamine into the sodium chloroacetate solution under constant stirring, and start adding sodium hydroxide solution dropwise when the pH of the system drops until the pH ≥14, when the pH of the system drops again, add sodium hydroxide solution dropwise, and repeat this until the pH does not change within 5.5 hours. The pH of the final ...
Embodiment 2
[0044] 2,4,6-Triamino-1,3,5-triazine-N-monoacetic acid
[0045] 6.33g (0.067mol) of monochloroacetic acid and 8.4g (0.067mol) of melamine were reacted according to the method of Example 1 to obtain the target product.
[0046] MS (ESP) m / z: 185 (M+1).
Embodiment 3
[0048] 2,4,6-Triamino-1,3,5-triazine-N,N (or N,N')-diacetic acid
[0049] 12.28g (0.13mol) of monochloroacetic acid and 8.4g (0.067mol) of melamine were reacted according to the method of Example 1 to obtain the target product.
[0050] MS (ESP) m / z: 243 (M+1).
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