Unlock instant, AI-driven research and patent intelligence for your innovation.

Residual disinfectant composition

a disinfectant composition and disinfectant technology, applied in the direction of biocide, paints, biocides, etc., can solve the problems of insufficient efficacy of disinfectant against non-enveloped viruses, inability to kill microorganisms on the surface, and disinfectant not typically persisting on the surfa

Active Publication Date: 2020-12-29
KIMBERLY-CLARK WORLDWIDE INC
View PDF70 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The composition achieves a log10 reduction of 1.5 or more in viral activity within 10 minutes and maintains residual antiviral efficacy for up to 48 hours, effectively inactivating non-enveloped viruses and other microorganisms on surfaces.

Problems solved by technology

Thus, most disinfectants have insufficient efficacy against these types of non-enveloped viruses.
Another problem with many conventional disinfectants is that they can kill microorganisms on surfaces when applied and allowed to remain in contact for a specific time, such as 10 minutes.
However, the disinfectant does not typically persist on the surface.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Residual disinfectant composition
  • Residual disinfectant composition
  • Residual disinfectant composition

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0160]A disinfectant composition was formed that contained 94.6 wt. % water, 1.25 wt. % of benzethonium chloride, 1.25 wt. % citric acid, 1.9 wt. % of Copolymer 958, 1.0 wt. % of Mirapol™ A 15. Copolymer 958 includes 50% vinylpyrrolidone / dimethylaminoethylacylrate in ethanol. Mirapol™ A 15 includes 60-70% Polyquaternium-2 in water. The final pH level was 2.76.

example 2

[0161]A disinfectant composition was formed that contained 94.35 wt. % water, 1.25 wt. % of benzethonium chloride, 1.5 wt. % maleic acid, 1.9 wt. % of Copolymer 958, 1.0 wt. % of Mirapol™ A 15. The final pH level was 1.42.

example 3

[0162]A disinfectant composition was formed as described in Example 2 except that the final pH was adjusted with sodium hydroxide to a level of 2.00.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
temperatureaaaaaaaaaa
lengthaaaaaaaaaa
lengthaaaaaaaaaa
Login to View More

Abstract

A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is the national stage entry of International Patent Application No. PCT / US2015 / 042209 having a filing date of Jul. 27, 2015, which is incorporated herein in its entirety by reference thereto.BACKGROUND OF THE INVENTION[0002]Pathogenic viruses are generally classified into two general types: enveloped and non-enveloped viruses. Some well-known enveloped viruses include herpes virus, influenza virus; paramyxovirus, respiratory syncytial virus, coronavirus, HIV, hepatitis B virus, hepatitis C virus, SARS-CoV, and togavirus. Non-enveloped viruses, sometimes referred to as “naked” viruses, include the families Picornaviridae, Reoviridae, Caliciviridae, Adenoviridae, Papovaviridae, and Parvoviridae. Members of these families include rhinovirus, poliovirus, adenovirus, hepatitis A virus, norovirus, papillomavirus, enterovirus, coxsackievirus, and rotavirus. “Enveloped” viruses are relatively sensitive and, thus, can be inactivat...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(United States)
IPC IPC(8): A01N25/10A01N37/36A01N25/34A61L2/18C09D7/61C09D7/63A01N25/04A01N59/26C09D5/14A01N25/30A01N33/12C09D139/06A01N43/36
CPCA01N33/12A61L2/18C09D7/63A01N25/34C09D7/61A01N25/04A01N59/26A01N37/36C09D139/06A01N25/10C09D5/14A01N37/02A01N37/06A01N41/04A01N43/36A01N47/28Y02A50/30A01N25/30
Inventor VANDEN HEUVEL, AMY L.HOFFMAN, DOUGLAS R.PAULSEN, JEREMY D.VONGSA, REBECCAANUNSON, PAIGE N.KROLL, LISA M.CUNNINGTON, COREY T.KOENIG, DAVID W.
Owner KIMBERLY-CLARK WORLDWIDE INC