Gastrointestinal anchor with optimal surface area

a surface area and gastrointestinal technology, applied in the field of gastrointestinal anchors, to achieve the effect of avoiding stomach wall folding, reducing tissue damage or device dislocation, and minimizing tissue stress

Inactive Publication Date: 2005-06-30
INTRAPACE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0006] In accordance with one aspect of the invention, the anchor distributes the load of the device on the stomach wall. According to the invention, the load to surface area distribution of the anchor is less than about five (5) grams per mm2 and preferably less than about one (1) gram per mm2. Accordingly, to an embodiment of the invention, the load is distributed relatively evenly on a surface area. However, it is contemplated that such load distribution may include an unevenly distributed load that has the same general effect of bearing the load of the anchor such that the anchor is less likely to erode through or dislodge.
[0009] An attachment device may be either integrally formed with the electronics unit or removably attachable to the electronics unit. The attachment device and electronics unit may be deployed in two steps: first by identifying a site for attachment and attaching the anchor and second by attaching the electronics unit. The electronics unit may be removable from the attachment device and or deployed electrodes so that the electronics unit may be replaced after time. The stimulating electrodes may be coupled to the attachment device and / or the electronics unit. The attachment device may include a release mechanism for easy endoscopic removal of the stimulating device from the stomach.
[0019] The present invention also provides an attachment device for attaching a functional device to the stomach wall. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The devices may be attached to the attachment device in a separate housing or may be integral with the attachment device. The functional devices may be powered by a battery included with the device or the functional devices may be inductively powered. In one embodiment, the attachment device is attached such that the device does not substantially constrain the stomach in the plane of smooth muscle contractions and to minimize stresses in the tissue, to reduce the potential for tissue damage or device dislodgement. Preferably the attachment device attaches in a manner that avoids folding of the stomach wall. In one preferred embodiment, the attachment device is attached by piercing at least a portion of the stomach wall at a single point of penetration into the stomach wall. Also, in one embodiment the attachment device pierces the stomach wall in a direction perpendicular to the natural orientation of the stomach wall. Further, in a preferred embodiment, the attachment device extends through the stomach wall with a backing mechanism located external to the stomach wall. Preferably such backing mechanism is relatively atraumatic to the stomach outer wall and surrounding tissue and has a relatively high surface area in relation to the width of the attachment device or puncture hole. In particular the ratio of weight to surface area is about 5 g / mm2 or less, preferably about 1 g / mm2 or less and more preferably about 0.1 g / mm2 or less. Another preferred embodiment provides an adjustable bumper holding the anchor to the inside of the stomach wall. Such bumper is also preferably designed to have a relatively high surface area and to be relatively atraumatic to the stomach wall. Another preferred embodiment provides an attachment device with a quick release mechanism that enables relatively easy endoscopic removal of the attachment device from the stomach.

Problems solved by technology

However, it is contemplated that such load distribution may include an unevenly distributed load that has the same general effect of bearing the load of the anchor such that the anchor is less likely to erode through or dislodge.

Method used

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  • Gastrointestinal anchor with optimal surface area
  • Gastrointestinal anchor with optimal surface area
  • Gastrointestinal anchor with optimal surface area

Examples

Experimental program
Comparison scheme
Effect test

first embodiment

[0054] Referring to FIGS. 10-14 and 18-22, a stimulator 10 of a first embodiment is illustrated. The stimulator 10 comprises an anchor 123 and a main body portion 20. The anchor 123 comprises an elongate member 124 having and expandable distal end 125 and a stimulating electrode 126 in the form of a ring of a corrosion resistant metal conductor such as Platinum, Gold, Tantalum, Titanium or suitable alloys thereof, extending around the elongate member 124 just proximal of the expandable end 125. The anchor 123 may be constructed of a radiopaque material. Alternatively, the anchor 123 may include radiopaque markers located on the device so that the location and orientation of the device may be identified, particularly after it has been placed. At least a portion of the anchor 123 is preferably coated with an antibiotic material, such as gentamicin sulphate or a silver / silver salts coating, particularly in locations that it will extend through or come in contact with the stomach wall. ...

second embodiment

[0072]FIGS. 23 and 24 illustrate the stimulator of the present invention. Stimulator 210 comprises a main body portion 220 and an anchor 223. The anchor 223 comprises an elongate proximal member 225. The elongate proximal member 225 includes a tether opening 235 in the proximal end, electrical contacts 228, 238, and a notch 227 for connecting the main body portion 220 to the anchor 223. The distal portion 240 of the anchor 223 comprises two prongs 241, 242. Prongs 241, 242 have expandable distal ends 243, 244 respectively that are constructed in a similar manner as the expandable distal end 125 described above with respect to the first preferred embodiment. A stimulating electrode 245 is located on prong 241 and an electrically opposite second stimulating electrode 246 is located on prong 242. Stimulating electrode 245 and second stimulating electrode 246 are coupled to electrical contacts 228 and 238 respectively by conductors 229 and 239 extending through prongs 241, 242 respectiv...

third embodiment

[0084]FIGS. 27A and 27B illustrate the present invention showing an anchor device for use with a stimulator or other functional device of the present invention. The anchor 263 comprises an elongate body 264, an expandable distal portion 265 having a sharp tip 270, a bipolar electrode pair 266, 267, and a bumper 275 located on a proximal portion of the elongate body 264. The expandable distal portion 265 comprises a flexible disk 271 for engaging the outer stomach wall. The disk 271 has an inner surface 271 a that interfaces with the outer surface 100a of stomach wall 100 and may, for example be coated with an antibiotic material, such as gentamicin sulphate or a silver / silver salts coating such as a powder. The bipolar stimulating electrode pair comprises electrode 266 located on the elongate body 264 and a plurality of electrodes 267 electrically opposite from electrode 266, located at the end of the expandable distal portion 265. The electrodes may be separately coupled to electri...

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PUM

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Abstract

A device, system and method for anchoring a device to a stomach is provided. The device may be, among other things, a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The anchor of the device is constructed to resist pull out forces. An anchor has an optimal weight to surface area ratio.

Description

RELATED APPLICATION DATA [0001] This application is a continuation in part of U.S. application Ser. No. 10 / 295,115, filed Nov. 14, 2002, which is a divisional of U.S. application Ser. No. 09 / 847,884 filed May 1, 2001 all of which are incorporated herein by reference.FIELD OF THE INVENTION [0002] This invention relates to an anchor for attaching a device to the stomach. BACKGROUND OF THE INVENTION [0003] Attaching devices to the stomach has a number of challenges including avoiding detachment, for example, due to the contractions of the stomach dislodging the device. In particular, attaching device to the inside of the stomach wall has been challenging for a variety of reasons. The inside of the stomach is highly acidic and the stomach wall tends to remodel making it difficult to retain a device attached to the stomach wall. Attaching a device to the stomach becomes more difficult where the stomach is more active or contractile, for example, in the antrum region. Also the purpose of ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B17/00A61F5/00A61M25/02A61N1/36
CPCA61B5/4238G01N27/126A61B17/3421A61B17/3478A61B2017/00004A61B2017/00017A61B2017/00026A61B2017/00084A61B2017/00477A61B2017/306A61B2017/3488A61F5/0003A61M25/02A61M2025/0233A61M2025/028A61N1/0509A61N1/0517A61N1/36007A61N1/372A61B5/6882
Inventor IMRAN, MIR A.
Owner INTRAPACE
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