Methods for the treatment of erectile dysfunction using fispemifene

a technology of erectile dysfunction and fispemifene, which is applied in the field of treatment of erectile dysfunction using fispemifene, can solve problems such as insufficient responsiveness, and achieve the effect of improving erectile function
US20080312239A1Inactive Publication Date: 2008-12-18QUATRX PHARMA
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
QUATRX PHARMA
Publication Date
2008-12-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

A method of treatment of erectile dysfunction (ED) comprises the step of administering fispemifene to a subject in need thereof in an amount effective to raise the subject's testosterone level. Fispemifene may be used in combination with a PDE-5 inhibitor in individuals who have failed to respond sufficiently to conventional ED treatment. Methods are also disclosed of treating ED by administering clomifene, enclomifene, ospemifene, toremifene and mixtures thereof in combination with a PDE-5 inhibitor.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of U.S. Provisional Patent Application No. 60 / 943,706, filed Jun. 13, 2007, hereby incorporated by reference.FIELD OF THE INVENTION

[0002] The invention relates to a method for treatment of erectile dysfunction (“ED”) using fispemifene, including: the use of fispemifene as a primary treatment for ED in individuals with low testosterone; the use of fispemifene in combination with another ED drug (such as type V phosphodiesterase (“PDE-5”) inhibitors) as combination therapy; and the use of fispemifene for the treatment of ED in individuals who have failed treatment with a PDE-5 inhibitor. The invention also relates to the use of selective estrogen receptor modulators (SERMs) including, but not limited to, fispemifene, clomifene, enclomifene, ospemifene, toremifene, afimoxifene, arzoxifene, bazedoxifene, lasofoxifene, ormeloxifene, raloxifene, tamoxifen, droloxifene, levormeloxifene, and idoxifene and mixtur...

Claims

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