Use of chemotherapeutic agents

Abstract

The use of chemotherapeutic agents for the preparation of a medicament for the topical and/or local treatment of diseases caused by bacteria and/or for prophylaxis in humans or animals.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is a divisional application of U.S. patent application Ser. No. 10 / 168,441, filed on Jun. 21, 2002, which was filed under International Application No. PCT / EP00 / 13155 filed Dec. 22, 2000, which claims priority to German Patent Application 199 62 470.4 filed Dec. 22, 1999 (the entire disclosures of which are incorporated herein by reference).BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates to the use of chemotherapeutic agents for the preparation of a medicament for the topical and / or local treatment of diseases caused by bacteria and / or for prophylaxis in humans or animals.[0004]2. Description of Related Art[0005]Bacteria can be the cause of a large number of diseases and can moreover impair wound healing. In the oral region, for example, tooth decay (caries) is caused by microbes specific to the mouth. Oral bacteria convert dietary carbohydrates to acids capable of dissolving ...

AI Technical Summary

Benefits of technology

[0018]Accordingly, given the current state of the art, there is also a need in human and veterinary medicine for topically and / or locally applicable agents with an antibiotic action which have a high activity against the microbes occurring in wounds, have a rapid bactericidal action, have a good local tolerability, elicit a low tendency to generate antibiotic resistance, are easy to administer by topical and / or local application, place a minimum systemic burden on the organism when administered topically / locally, have a good tissue penetration, are also suitable for the treatment of deep infections and additionally accelerate the wound healing process.

Problems solved by technology

The particular problems associated with treatment of the pulp are the small lymph supply, its position as a terminal organ with a small collateral circulation, and the influence of external stimuli given its location in a rigid, inflexible cavity.

The particular problem associated with the diagnosis of a pulp disease is that the histological and clinical pictures are often quite different.

As pain is sensed and interpreted differently by different patients, there is always the risk of a false diagnosis.

Under the conventional treatment, there is then the danger of residual microbes being left behind.

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