Unlock instant, AI-driven research and patent intelligence for your innovation.

Enhanced ingestible event indicators and methods for making and using the same

a technology of event indicators and ingestible materials, applied in the field of enhanced ingestible event indicators and methods for making and using the same, can solve the problems of potentially harmful to the surrounding environment and costly production of power sources

Inactive Publication Date: 2016-12-01
OTSUKA PHARM CO LTD
View PDF8 Cites 25 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent text describes enhanced ingestible event markers that can be used to detect the passage of something through a person's body. The markers have a layer of material with a binder and an electron acceptor, which can create a voltage potential difference when in contact with a conductive fluid. There is also a large surface area electrode that can be seen by a receiver. The markers can be controlled by a logic module to produce a signal that can be detected. The system may also include a control device with a logic module and an acidulating agent. The markers can be used to track the movement and behavior of objects in the body. The technical effects of the patent text are the improved detection and monitoring of objects in the body using enhanced ingestible event markers.

Problems solved by technology

Among the many shortcomings of existing devices is that the power source is internal to device and such power sources are costly to produce and potentially harmful to the surrounding environment if the power source leaks or is damaged.
Additionally, having antennas extending from the device is a concern as related to the antennas getting damaged or causing a problem when the device is used in-vivo.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Enhanced ingestible event indicators and methods for making and using the same
  • Enhanced ingestible event indicators and methods for making and using the same
  • Enhanced ingestible event indicators and methods for making and using the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033]Enhanced ingestible event markers are provided. Aspects of the markers may include the presence of a matrix layer that includes a binder and source of an electron acceptor. Alternatively or in addition to the matrix layer, aspects of the markers may include a large surface area electrode having a surface area that exceeds the surface area of the circuitry of the marker. Aspects further include methods of making and using the ingestible event markers.

Ingestible Event Markers

[0034]As summarized above, aspects of the invention include improved ingestible event markers (IEMs). In describing various aspects, the ingestible event markers will be described first in general terms, followed by a detailed description of the matrix and high surface area electrode aspects which may be present in the ingestible event markers.

[0035]Ingestible event markers are ingestible devices. As the ingestible event markers are ingestible, they are configured to be ingested or swallowed, i.e., taken int...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Improved ingestible event markers are provided. Aspects of the markers may include the presence of a matrix layer that includes a binder and source of an electron acceptor. Alternatively or in addition to the matrix layer, aspects of the markers may include a large surface area electrode having a surface area that exceeds the surface area of the circuitry of the marker. Aspects further include methods of making and using the ingestible event markers.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to U.S. Provisional Application No. 61 / 935,768, filed Feb. 4, 2014, entitled ENHANCED INGESTIBLE EVENT INDICATORS AND METHODS FOR MAKING AND USING THE SAME, the disclosure of which is incorporated herein by reference in its entirety.INTRODUCTION[0002]A variety of different ingestible compositions have been developed for nutritional, therapeutic and non-therapeutic uses. Examples of different types of ingestible compositions include orally ingestible tablets, capsules and liquids. A given orally ingestible formulation may include a variety of different components, such as active agents, carrier materials (including binders, bulking agents and other excipients), flavoring agents, coloring agents, etc.[0003]More recently, ingestible compositions which include a device component, such as an ingestible event marker, have been developed. Use of such ingestible devices allows one to monitor the actual ingestion o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61B5/00A61B5/1473A61B5/07
CPCA61B5/6861A61B5/073A61B2562/125A61B5/4839A61B5/7282A61B5/1473A61K9/20A61K9/0097
Inventor JOHNSON, PATRICIASCHMIDT, RAYMONDPATEL, ANUJCHENG, KEVINIWAI, KOSUKEHAFEZI, HOOMAN
Owner OTSUKA PHARM CO LTD