Antiseptic, antiseborrheic and exfoliating composition to remove or prevent acne

Abstract

The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.

Description

RELATED APPLICATIONS[0001]This application is a continuation of U.S. application Ser. No. 14 / 421,616, filed on Feb. 13, 2015, which is a 35 U.S.C. 371 National Stage Filing of International Application No. PCT / MX2013 / 000099, filed on Aug. 22, 2013, which claims priority to Mexican Application No. MX / A / 2012 / 009806, filed on Aug. 23, 2012. The contents of the aforementioned applications are hereby incorporated by reference in their entireties.FIELD OF THE INVENTION[0002]The present invention relates to a hydrosoluble pharmaceutical antiseptic, antiseborrheic and exfoliating composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid) to remove bacteria affecting the skin, besides said composition provides a deep cleansing because it reduces the epidermal cohesion and facilitates the cellular replacement, preventing or removing the occurrence of several forms of alterations in the skin.BACKGROUND OF THE INVENTION[0003]T...

AI Technical Summary

Benefits of technology

The present invention provides pharmaceutical hydrosoluble compositions that combine diallyl disulphide modified oxide (DDMO) and alpha-hydroxyethanoic acid (glycolic acid) to remove or prevent acne. These compositions have antimicrobial, exfoliating, and seboregulating properties, which help to keep the skin clean and healthy.

Problems solved by technology

The resulting corneous material fall in the light of the follicle, which in addition to the fat excess forms wax substituting and easing the follicle walls, accordingly by not being able to excrete material, it inflames more, causing the first and most important acne elemental injury: the blackhead, causing dilation of the follicular hole due to the pressure the wax applies when trying to be expelled.

Since it is a not much stable compound, the DDO quickly loses its properties, on the other hand if garlic is heated over 60° C. it loses its properties.

It has a strong oxidative power that could cause harm to intestinal cells.

In 1944 Cavallito and his co-workers were able to isolate and identify the active compound from the extracts of Allium sativum which they called allicin and in 1947 they were able to synthesize the diallyl disulphide oxide (allicin), but unfortunately they were not able to make the molecule thereof stable, since it kept losing its efficacy in a very short period of time.

In diverse studies it has been shown the activity of allicin, however its little stability has been a limitation in its possible therapeutic applications.

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