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30 results about "Diallyl disulphide" patented technology
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Diallyl disulfide (DADS or 4,5-dithia-1,7-octadiene) is an organosulfur compound derived from garlic and a few other genus Allium plants. Along with diallyl trisulfide and diallyl tetrasulfide, it is one of the principal components of the distilled oil of garlic.
Valid target of garlic oil and the application in preparing many kinds of medicine
InactiveCN101040995ABiologically activeSmall side effectsAntibacterial agentsOrganic active ingredientsAntibiosisSide effect
The invention relates to an effective part of Chinese drug and relative application, wherein, the effective part is a compound whose main components are allyl disulfide (DADS) and methacrylic trisulfide (MATS), without diallyl trisulfide (DATS) as allicin, while the effective part is significant different from garlic oil in quality and quantity, which is separated and extracted from garlic oil. The effective part has the functions as antibiosis and antiviral (as anti-AIDS and anti-herpesvirus) outside the body, and the anti-tumor function (as anti-leukemia), and anti-thrombus) function. Compared with allicin, the invention has high stability and low side effect, while the effective part can be used to prepare the drug for treating virus, bacterial, tumor and thrombus, with wide clinic application.
Owner:沈联慈 +1
Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (m-ddo) for eliminating or preventing acne
ActiveUS20160228424A1Eliminating and reducing and preventing occurrenceReducing and preventing acneAerosol deliverySulfur/selenium/tellurium active ingredientsAntiseptic AgentDisulfide bond
The instant invention relates to a semi-solid topical composition containing Pirfenidone and an antimicrobial / antiseptic agent such as Modified Diallyl Disulfide Oxide (M-DDO) and its preparation process, offering advantages compared to other pharmaceutical forms of topical administration known in the state of the art, useful as antifibrotic, anti-inflammatory and antiseptic agent in the prevention, treatment and reversion of acne and post acne lesions. Said compositions is also useful for reducing skin redness, detaining the formation of new acne outbreaks, reversing already existing outbreaks and regenerating skin damage caused by acne.
Owner:EXCALIBUR PHARM INC
Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne
ActiveUS9949959B2Eliminating and reducing and preventing occurrenceReducing and preventing acneAerosol deliverySulfur/selenium/tellurium active ingredientsDiallyl disulfide-oxidePreservative
The instant invention relates to a semi-solid topical composition containing Pirfenidone and an antimicrobial / antiseptic agent such as Modified Diallyl Disulfide Oxide (M-DDO) and its preparation process, offering advantages compared to other pharmaceutical forms of topical administration known in the state of the art, useful as antifibrotic, anti-inflammatory and antiseptic agent in the prevention, treatment and reversion of acne and post acne lesions. Said compositions is also useful for reducing skin redness, detaining the formation of new acne outbreaks, reversing already existing outbreaks and regenerating skin damage caused by acne.
Owner:EXCALIBUR PHARM INC
Antiseptic, antiseborrheic and exfoliating composition to remove or prevent acne
The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.
Owner:EXCALIBUR PHARM INC
Antiseptic, antiseborrheic, exfoliating composition for getting rid of or preventing acne
The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.
Owner:EXCALIBUR PHARM INC
Antiseptic, antiseborrheic and exfoliating composition to remove or prevent acne
ActiveUS20190290606A1Prevent removalAntibacterial agentsCosmetic preparationsAntiseptic AgentPharmacology
The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.
Owner:EXCALIBUR PHARM INC
Method for preparing 2,5-dimercapto-methyl-1,4-dithiane
InactiveCN101787014AHigh refractive indexLow refractive indexOrganic chemistryDithianeHeat resistance
The invention relates to a method for preparing 2,5-dimercapto-methyl-1,4-dithiane, which belongs to the field of optical materials. A reaction formula is as follows: Na2S.9H2O+S->Na2S22CH2=CHCH2Cl+Na2S2->CH2=CHH2-S-S-CH2CH=CH2. The method comprises the following steps of: (1) synthesizing diallyl disulfide; (2) synthesizing 2,5-bis (chloromethyl)-1,4-dithiane; (3) and synthesizing the 2, 5-dimercapto-methyl-1,4-dithiane. The 2,5-dimercapto-methyl-1,4-dithiane provided by the invention is used to prepare novel optical materials, and has refractive indexes with high dispersion and low dispersion. The 2,5-dimercapto-methyl-1,4-dithiane has the advantages of light weight, colorless, transparence and optical distortion, excellent weatherability, dye affinity, heat resistance, impact resistance and machining performance. The method provided by the invention is simple and practicable, and the yield can be up to 65%.
Owner:JIANGSU POLYTECHNIC UNIVERSITY
Preparation method of Korean pickled vegetable essence
ActiveCN110140935AFragrance aroma is pure and fullIncrease the fragranceClimate change adaptationAcidic food ingredientsPropanoic acidAllyl thiocyanate
The invention provides a preparation method of Korean pickled vegetable essence. The disclosed Korean pickled vegetable essence comprises the ingredients of Caprylic capric triglycerride,, dimethyl disulfide, dimethyl trisulfide, diallyl sulfide, dimethyl sulfide, diallyl disulfide, 3-methylthiopropanol,, star anise essential oil, cinnamon essential oil, fresh ginger essential oil, chili pepper essential oil, propanoic acid, acetic acid, ethyl caprylate, ethyl caprate, ethyl acetate, 3-methylthiopropyl aldehyde and allyl isothiocyanate. The prepared pickled vegetable essence has the characteristics of being real and natural in fragrance, rich in mouth feel and stable in flavor, the appetence degree of a consumer is increased, and the Korean pickled vegetable essence can be well applied tothe field of foods of leisure puffed foods and the like.
Owner:江西省华宝孔雀食品科技发展有限公司
Waste tire rubber powder modified asphalt and preparation method thereof
InactiveCN105602265AReduce energy consumptionEmission reductionBuilding insulationsToxic gasDodecane
The invention discloses a waste tire rubber powder modified asphalt which is prepared from the following raw materials in parts by weight: 45-55 parts of matrix asphalt, 18-28 parts of waste tire rubber powder, 3-6 parts of polyethylene wax, 8-11 parts of 3-(dodecaalkoxy)-2-hydroxypropyl-N-acetoxy-N,N-dimethylammonium chloride, 4-7 parts of pine tar, 2-5 parts of diallyl disulfide, 1-3 parts of cyclic monosulfide and 5-8 parts of modifier. The modifier is composed of the following raw materials in parts by weight: 23-27 parts of dodecylphosphate, 13-21 parts of stearic acid, 5-10 parts of sodium lignosulfonate, 1-3 parts of butyl amine and 3-7 parts of diimidazoline. The rubber powder modified asphalt mixture obviously lowers the temperature in the production, spreading and rolling process, thereby lowering the energy consumption, reducing the emissions of dense smoke and toxic gas, promoting the large-scale popularization and application of the rubber powder modified asphalt mixture, and being beneficial to promoting the recycling of waste tires. Thus, the waste tire rubber powder modified asphalt solves the problem of severe environmental pollution caused by the traditional waste tire treatment mode composed of piling, landfilling and incineration, and also solves the problems of severe technique pollution and high energy consumption caused by tire devulcanization regeneration.
Owner:江苏文昌新材料科技有限公司
Lithium metal with rigid-elastic interface layer as well as preparation method and application of lithium metal
PendingCN110911683AIncrease elasticityImprove toughnessFinal product manufactureCell electrodesPolymer networkPhysical chemistry
The invention provides lithium metal with a rigid-elastic interface layer as well as a preparation method and application of the lithium metal, and belongs to the field of lithium metal batteries. Diallyl disulfide (DADS) is electrochemically deposited on the surface of lithium metal in situ to form an inorganic-polymer structure, so that the lithium metal has a rigid-elastic interface layer at the same time. The polymer network improves the elasticity and toughness of the interface layer, and the formed inorganic unit can provide higher mechanical strength to resist the damage of lithium dendrites. Therefore, the interface layer not only can inhibit the formation of lithium dendrites, but also can enable the deposition / stripping behavior of lithium to be carried out more quickly and stably.
Owner:四川创微致尚科技有限公司
Prepared meat-flavor oily essence and preparation method thereof
ActiveCN102626215BGood aroma and fragrance stabilityGood aroma effectFood preparation2-methyl-3-furanthiol4-methyl-5-thiazoleethanol
The invention relates to prepared meat-flavor oily essence and a preparation method thereof. The prepared meat-flavor oily essence is prepared through the following method that: monomer fragrance raw materials such as 2-methyl-3-furathiol, dual (2-methyl-3-furathiol), trans, trans-2, 4-decadienal, 4-hydroxy-2,5-dimethyl 3(2H)-furanone, trans, trans-2,4-heptadiene aldehyde, trans, trans-2,4-nonadienal, 2,3,5-trimethyl pyrazine, 5-methyl-furfural, diallyl disulfide ether, 4-methyl-5-thiazoleethanol, 2,3-dimethyl pyrazine, difurfuryldisulfide, distilled ginger oil, green Chinese onion oil, onion oil, 2-acetyl-furan, 3-mercapto-2-butanol, cassia oil, star anise oil, 3-methylthio propyl alcohol, butanedione and soy fouranone are respectively diluted by soybean oil to a stipulated concentration, then the diluted fluid is uniformly mixed, finally the soybean oil is used as a solvent to supply the 100 percent, and an essence finished product is prepared. Note of the essence consists of meat note, butter note, burnt odor, spice, delicate green note, nut note and onion and ginger note.
Owner:TIANJIN CHUNFA BIO TECH GRP
Topical semisolid composition containing an antimicrobial agent and pirfenidone for the treatment of chronic skin damage
ActiveUS20200253944A1Eliminate, reduce or prevent chronic skin lesionsOrganic active ingredientsOintment deliveryDiabetic footAntiseptic Agent
The invention provides topical pharmaceutical gel compositions for the treatment of chronic skin damage, specifically for damage caused by neuropathic ulcers and preferably for the treatment of diabetic foot, and in the treatment of vascular ulcers wherein said compositions comprise a combination of Modified Diallyl Disulfide Oxide (M-DDO) (as an antiseptic / antibiotic agent) and 5-methyl-1-phenyl-2(1H)-pyridone.Furthermore, the invention describes methods of treatment, applications and / or pharmaceutical uses in the preparation of medicaments for eliminating, reducing or preventing chronic skin lesions and the damages caused by neuropathic ulcers and particularly in the treatment of diabetic foot and in the treatment of vascular ulcers.
Owner:EXCALIBUR PHARM INC
Environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and production technology and use method thereof
The invention provides an environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and a production technology and a use method thereof. The fertilizer is a neutral or weakly acidic fertilizer, and contains a diallyl disulfide and diallyl trisulfide mixture. The pH value of a saturated aqueous solution of the fertilizer can be 5-7, and preferably 6.5-7. The fertilizer can have the following one or more characteristics: 1, a compound fertilizer or a composite fertilizer; 2, a slow release fertilizer or a controlled release fertilizer; 3, an organic fertilizer or an inorganic fertilizer or an organic-inorganic compound fertilizer; 4, urea, a urea-ammonium mixed nitrogen fertilizer and polypeptide urea; 5, monoammonium phosphate and diammonium phosphate; and 6, potassium chloride and potassium sulfate. The fertilizer can provide crop nutrients, effectively purifies soil and control the diseases and insect pests of crops, and diallyl disulfide and diallyl trisulfide are from garlic extracts, are most safe biological pesticides proved in the laboratory at present, have no toxic side effects, no drug residual and no drug resistance, and are best additives substituting antibiotics to produce nuisance free products.
Owner:朱崇靖
Feed capable of reducing the cholesterol content in duck eggs
InactiveCN103598423AReduce egg yolk cholesterol contentReduce concentrationAnimal feeding stuffYolkAnimal science
The invention discloses feed capable of reducing the cholesterol content in duck eggs. The feed is prepared by adding 200-800 mg / kg of garlic oil to complete-feed basic ration, wherein the main components of the garlic oil are diallyl disulfide and diallyl trisulfide, and the content of the garlic oil is larger than 10.5%. The feed provided by the invention can significantly reduce the feed-egg ratio and reduce deposition of the cholesterol in egg yolks, and therefore the feed provided by the invention has significant practical meaning for development of low-cholesterol health-care duck eggs and for sustainable development of the whole laying-duck industry.
Owner:HUNAN AGRICULTURAL UNIV
Alliin-based antibiotic-replacement feed synbiotic composition and preparation method thereof
InactiveCN111838423ANot volatileEasy to acceptAnimal feeding stuffAccessory food factorsSynbioticsLichen
The invention discloses an alliin-based antibiotic-replacement feed synbiotic composition, and relates to an alliin-based antibiotic-replacement feed synbiotic composition and a preparation method thereof. The allicin is allicin which is obtained through natural fermentation treatment and contains stable sulfide components, and comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS). Theprobiotics is selected from one or combination from lactic acid bacteria and bacillus licheniformis; bacillus subtilis, bifidobacterium bifidum, enterococcus faecalis, enterococcus faecium, lactobacillus acidophilus, lactobacillus casei, lactobacillus plantarum, pediococcus pentosaceus, the invention discloses rhodopseudomonas palustris. The composition is one or a combination of more of bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, bifidobacterium animalis, bifidobacterium adolescentis, streptococcus thermophilus, lactobacillus reuteri, aspergillus niger, aspergillus oryzae, bacillus tarda, bacillus pumilus, lactobacillus cellobiosus, lactobacillus fermentum, lactobacillus bulgaricus, lactobacillus buchneri and bacillus laterosporus. The method is used for special breeding environments with aseptic requirements, improving the water source environment of farms and the like.
Owner:山东健为生物科技有限公司
Extraction of garlic volatile oil
The invention discloses a preparation method of garlic oil, which comprises the steps of crushing garlic into different particle sizes according to the different contents of diallyl trisulfide and diallyl disulfide in the required garlic oil, and adding water to keep warm for enzymolysis , Steam distillation extracts volatile oil, dehydrates volatile oil with water, and obtains garlic oil. In the preparation process of garlic oil, the present invention can increase the content of diallyl trisulfide in the obtained garlic oil, or increase the content of diallyl disulfide, or The contents of the two are relatively in the middle, so as to meet the needs of medical products or health products for different treatments.
Owner:INST OF BASIC THEORY OF TCM CHINA ACADEMY OF CHINESE MEDICAL SCI
Odorless garlic ferment and preparation method thereof
PendingCN111773303ANot volatileEasy to acceptOrganic active ingredientsDigestive systemAllium sativumSulfide compound
The invention discloses odorless garlic ferment, and relates to odorless garlic enzyme and a preparation method thereof. The odorless garlic ferment is characterized by comprising amino acids and garlic polysaccharides which are obtained by fermenting and decomposing proteins contained in allicin and garlic, wherein the allicin comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS), andthe allicin is stable allicin which is obtained through natural fermentation treatment and contains sulfide components. The method disclosed by the invention is simple in process, the produced odorless garlic ferment is particularly stable, can be stored for more than two years or even longer for a long time, is lower in cost and is easy for industrial popularization. Supernatant stored after standing for a long time can become acidic sterile liquid, can be exposed to an open environment for a long time, and can be used in special environments with sterile requirements.
Owner:山东健为生物科技有限公司
Natural-allicin-containing antibiotic-replacing feed and preparation method thereof
PendingCN111938019ANot volatileNot easy to decomposeFood preservationAnimal feeding stuffBiotechnologyGrowth promoting
The invention relates to the technical field of feed processing, in particular to a natural-allicin-containing antibiotic-replacing feed and a preparation method thereof. Raw materials containing natural allicin comprise allicin, protein contained in garlic, and amino acid and garlic polysaccharide obtained through decomposition after fermentation, the allicin comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS), and the allicin is stable allicin which is obtained through natural fermentation treatment and contains sulfide components. Volatilization and decomposition cannot easilyoccur; acceptance and popularization are facilitated; and no drug dependence is generated, and no residues are left. According to the natural-allicin-containing antibiotic-replacing feed, no antibiotics areadded in the breeding process, the growth promoting effect of antibiotics can be replaced, and the feed has the effects of mold prevention, sterilization and the like and is not prone to being contaminated in the transportation and storage processes; the feed is simple in process, wide in application range and suitable for most cultured animals; and the feed can be stored for more than two years or even longer, and is low in cost and easy to popularize industrially.
Owner:山东健为生物科技有限公司
Bactericidal composition and application thereof
PendingCN113476434AAvoid problemsObvious therapeuticAntimycoticsPharmaceutical non-active ingredientsBiotechnologyDisease
The invention discloses a bactericidal composition. The bactericidal composition is prepared from diallyl disulfide and methane dithiocyanate, the mass ratio of the diallyl disulfide to the methane dithiocyanate is (1-20): (1-8), and the bactericidal composition belongs to the technical field of prevention and treatment of diseases of aquaculture animals. The bactericidal composition provided by the invention further comprises application of the bactericidal composition in preparation of drugs for preventing or treating aquaculture diseases. The bactericidal composition has a good prevention effect on saprolegniasis of grass carps or crucian carps.
Owner:湖北至正天辰生物科技有限公司
Method for improving garlic oil yield
InactiveCN101985578BIncrease productionShorten distillation timeEssential-oils/perfumesAllyl methyl sulfideDistillation
The invention discloses a method for improving garlic oil yield, which comprises: soaking fresh garlic or dry garlic slices in water; stirring for removing impurities such as soil; feeding the fresh garlic or dry garlic slices in a pulping machine and crushing; adding an allinase activity regulator; performing enzymolysis; adding a transforming agent; feeding; distilling; feeding distillate into distilling equipment; taking an oil phase out, wherein the oil phase is coarse garlic oil; drying the garlic oil by a silicagel column; and removing residual moisture and obtaining the garlic oil. The method has the main advantages that: when the proper transforming agent is added, the distillation time is reduced by 20 percent, the garlic oil yield is improved to 1 to 3 times, and the content of each of the components such as diallyl disulfide, diallyl trisulfide, diallyl sulfide, allyl methyl sulfide, allyl methyl disulphide, allyl methyl trisulphide, propenethiol and methyl merecaptan is improved to over 3 times; and equipment investment is not increased, as only a proper amount transforming agent is added on the basis of the original distillation garlic oil production line.
Owner:JINAN UNIVERSITY
Polyacrylic acid-based self-healing elastic material as well as preparation method and application thereof
The invention discloses a polyacrylic acid-based self-healing elastic material as well as a preparation method and application thereof. According to the olyacrylic acid-based self-healing elastic material, a copolymer formed by photopolymerization of three monomers of hydroxyethyl acrylate, hydroxyethyl methylacrylate and methacrylic acid serves as a three-dimensional network skeleton, and low-molecular-weight polyacrylic acid penetrates through a three-dimensional network to prepare the elastomer. Meanwhile, diallyl disulfide is introduced as a cross-linking agent and a modifier, a dynamic reversible disulfide bond exchange network is constructed, and the diallyl disulfide cooperates with a large number of hydrogen bonds in the system to endow the elastomer with good self-healing performance. The polyacrylic acid-based self-healing elastomer prepared by the invention has good self-healing property, certain mechanical strength and toughness and higher transparency, can be used for preparing mobile phone protective jackets, table mats, toys, entity signs and the like, and has wide application value.
Owner:SOUTH CHINA UNIV OF TECH
Composite garlic peptide fermentation liquor, composite garlic peptide fermentation powder and preparation method of composite garlic peptide fermentation liquor and composite garlic peptide fermentation powder
PendingCN114097932ANot volatileGreat tasteFood processingAnimal feeding stuffBiotechnologyGARLIC POWDER
The invention belongs to the technical field of feed raw material processing, and particularly relates to a composite garlic peptide fermentation liquid, composite garlic peptide fermentation powder and a preparation method thereof, the composite garlic peptide fermentation liquid comprises allicin, vegetable and fruit plant enzyme probiotics, and amino acid and garlic polysaccharide obtained by fermenting and decomposing protein contained in garlic; the allicin comprises diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS), the composite garlic peptide yeast powder is prepared by adding a proper amount of DDGS (dry whole grain stillage), meal or bran into garlic powder, vegetable and fruit plant enzymes and composite garlic peptide yeast liquid and performing proper low-temperature drying, and the composite garlic peptide yeast powder is naturally prepared and has resistance replacing and zinc limiting effects in the animal breeding process; the contained allicin is more stable, not easy to volatilize and long in storage life; the feed additive is good in palatability, can effectively regulate intestinal flora of animals and kill pathogenic bacteria, can regulate the micro-ecology of the animals in combination with vegetable and fruit plant enzymes, does not generate drug dependence, and is free of any residue.
Owner:山东春禾自然生物科技有限公司
Drug-loaded nano-micelle and preparation method thereof
PendingCN114748421AHigh encapsulation efficiencyHigh drug loadingOrganic active ingredientsPharmaceutical non-active ingredientsHemolysisPolyethylene glycol
The invention discloses a drug-loaded nano-micelle and a preparation method thereof, and a film hydration method is adopted to prepare a pH sensitive polymer polyethylene glycol 2000-distearoyl phosphatidyl ethanolamine (PEG2000-DSPE) and a DD / M nano-micelle of the polyethylene glycol 2000-distearoyl phosphatidyl ethanolamine (PEG2000-DSPE) entrapped with diallyl disulfide and adriamycin. Compared with the prior art, the DD / M nano-micelle prepared by co-encapsulating DADS and DOX is constructed by utilizing a nano-micelle carrier PEG2000-DSPE, the DOX and DADS encapsulation efficiency and drug loading capacity are relatively high, the particle size uniformity, dispersity and stability are good, a good pH responsive in-vitro drug release behavior is achieved, a good foundation is laid for subsequent experiments, the toxicity to normal cells is low, and the DD / M nano-micelle has a good application prospect. In addition, hemolysis cannot be caused, and good biocompatibility is achieved. Meanwhile, the DD / M nano-micelle disclosed by the invention has a good in-vitro proliferation inhibition effect on three types of liver cancer cells and has obvious time and dose dependence; the compound can be successfully taken by liver cancer cells, and has obvious slow release property.
Owner:NANHUA UNIV
Topical semisolid composition containing antimicrobial agent and pirfenidone for treatment of chronic skin damage
PendingCN111246840AReduce or prevent damageReduce or prevent injuryOrganic active ingredientsOintment deliveryDiabetic footMethyl palmoxirate
The invention provides a topical pharmaceutical gel composition. The topical medicinal gel composition is used for treating chronic skin injury, and is especially used for treating injuries caused byneurological ulcers. The present invention relates to the topical pharmaceutical gel composition for treating vascular ulcers, preferably diabetic feet, and for treating vascular ulcers, in which thecomposition comprises a combination of a modified diallyl disulfide oxide (M-DDO) (as preservative / antibiotic) and 5-methyl-1-phenyl-2 (1H)-pyridone. Furthermore, the present invention describes therapeutic methods, uses and / or uses for the preparation of medicaments for eliminating, reducing or preventing chronic skin lesions and lesions caused by neurological ulcers, in particular for the treatment of diabetic feet and for the treatment of vascular ulcers.
Owner:CELL THERAPY & TECH S A DE
Method for improving quality of functional onion vinegar in brewing process
PendingCN112538412AAntioxidantPrevent agglutinationMicroorganism based processesVinegar preparationBiotechnologySubmerged fermentation
The invention belongs to the field of onion vinegar production, and particularly discloses a method for improving the quality of functional onion vinegar in the brewing process. Aiming at solving problems that the traditional vinegar fermentation is open-type solid state fermentation, the content of harmful ingredients is relatively high and the continuous production cannot be realized, the methoduses onion as a raw material and adopts the Saccharomyces cerevisiae and Acetobacter aceti two-step liquid submerged fermentation technology, the change rule of flavonoid active substances in the brewing process is detected, and the content of active substances in the finished vinegar is reserved as much as possible; meanwhile, the method improves the health-care quality of the onion vinegar by reducing the content of harmful substances such as biogenic amines and urethane in the brewing process; furthermore, the method improves the flavor of the onion vinegar by embedding diallyl disulfide in the onion vinegar; and by integrating the characteristics, the method greatly improves the quality of the onion vinegar and is worthy of vigorous popularization.
Owner:JINHUA ACAD OF AGRI SCI +1
A kind of controllable and reversible crosslinking urushiol resin and preparation method thereof
ActiveCN108192042BImprove thermo-oxidative stabilityImprove insulation performanceAdditive manufacturing apparatusNatural resin coatingsPolymer scienceCross linker
The invention relates to controllably and reversibly crosslinked urushiol resin and a preparation method thereof. The preparation method of the controllably and reversibly crosslinked urushiol resin comprises the following steps: dissolving urushiol resin or a urushiol derivative and reversible crosslinking agent diallyl disulfide in a diluent in the mass ratio being 100:1-100:30, and uniformly stirring the substances to obtain the controllably and reversibly crosslinked urushiol resin. According to the controllably and reversibly crosslinked urushiol resin, content of carbon-carbon double bonds (C=C) in the resin can be changed by controlling dose of diallyl disulfide under ultraviolet irradiation, that is, controllable free radical crosslinking polymerization of the urushiol resin is realized by controlling content of free radicals. After crosslinking polymerization of the resin, reversible crosslinking functionalization of the urushiol resin can be realized by means of the characteristic that disulfide bonds in diallyl disulfide can be oxidized under the condition of a strong base into mercapto groups to be broken. The controllably and reversibly crosslinked urushiol resin is applicable to the fields of paint technology automation technique, additive manufacturing technique, raw lacquer coating, raw lacquer pigment and the like.
Owner:MINJIANG UNIV
Dewaxed garlic volatile essential oil and extraction method and application thereof
The invention provides dewaxed garlic volatile essential oil and an extraction method and application thereof, and relates to the technical field of volatile oil application. The extraction method takes garlic as a raw material to obtain a mixture containing essential oil through one-step extraction by a supercritical fluid extraction method, and performing elution, dehydration and ethanol recovery to obtain the dewaxed garlic volatile essential oil. The obtained dewaxed garlic volatile essential oil has a better inhibiting effect on tobacco black shank, the main active ingredient of the dewaxed garlic volatile essential oil is diallyl disulfide, and the dewaxed garlic volatile essential oil has a stronger fumigation effect on the tobacco black shank. Pot experiments show the diallyl disulfide treatment could significantly reduce the incidence of the tobacco black shank and the number of the tobacco black shank in rhizosphere soil. In addition, the compound use of carvacrol and the diallyl disulfide can significantly improve the control effect on the tobacco black shank, reduce the number of black shank bacteria in the soil, and also relieve garlic odor to some extent.
Owner:TOBACCO RES INST CHIN AGRI SCI ACAD
Medicine for reducing body injuries caused by influenza virus infection
InactiveCN105769832AReduce morbidityReduce mortalityOrganic active ingredientsAntipyreticInjury causeTerra firma
The invention provides a medicine for reducing body injuries caused by influenza virus infection.The effective ingredient is diallyl disulfide.According to the medicine, it is indicated that the diallyl disulfide has the protective effect on mice subjected to influenza virus infection for the first time, the found mechanism has high clinical significance, and a firm foundation is laid for optimizing prevention measures and treatment methods of influenza.
Owner:CHINA AGRI UNIV
A kind of cyanide-free silver plating pre-plating solution and preparation method thereof
Owner:CHONGQING LIDAO SURFACE TECH
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