Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

30 results about "Allyl trisulfide" patented technology

Diallyl trisulfide (DATS), also known as Allitridin, is an organosulfur compound with the formula S(SCH2CH=CH2)2. It is one of several produced by the hydrolysis of allicin, including diallyl disulfide and diallyl tetrasulfide, DATS is one of the most potent.

Valid target of garlic oil and the application in preparing many kinds of medicine

The invention relates to an effective part of Chinese drug and relative application, wherein, the effective part is a compound whose main components are allyl disulfide (DADS) and methacrylic trisulfide (MATS), without diallyl trisulfide (DATS) as allicin, while the effective part is significant different from garlic oil in quality and quantity, which is separated and extracted from garlic oil. The effective part has the functions as antibiosis and antiviral (as anti-AIDS and anti-herpesvirus) outside the body, and the anti-tumor function (as anti-leukemia), and anti-thrombus) function. Compared with allicin, the invention has high stability and low side effect, while the effective part can be used to prepare the drug for treating virus, bacterial, tumor and thrombus, with wide clinic application.
Owner:沈联慈 +1

Topical use of plant extract for skin detoxification

InactiveUS20090306219A1Maintain cellular redox homeostasisReduce hydrogen peroxideBiocideSulfur/selenium/tellurium active ingredientsPeroxideCollard Green
Specific plant extracts are applied topically to upregulate genes which code for proteins to prevent the build-up of and mitigate the activity of various harmful materials within the skin. These upregulated proteins include glutathione transferases, peroxiredoxins, oxidoreductases, glutaredoxins and glutathione syntheses. These proteins produce additional glutathione, glyoxalase I, maintain cellular redox homeostasis, reduce hydrogen peroxide and alkylhydroperoxides, and conjugate glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Keratinocytes have been induced to significantly upregulate glutathione and glyoxalase I protein expression. Additionally, keratinocytes pre-treated with diallyl trisulfide have increased viability when exposed to ozone, UV radiation or cigarette smoke extract. The active material can be extracted from plants such as garlic, onions, shallots, leeks, chives, scallions, brussel sprouts, broccoli, cabbage, cauliflower, bok choy, kale, mustard, turnip or radish, may include any compound of the allyl sulfide family, and may be of synthetic origin.
Owner:BEILIS DEV

Method of manufacture of garlic extract for use as a preventive and therapeutic agent for human prostate and bladder cancers

This invention is concerned with clinical investigation of therapeutic effects of garlic extracts containing allicin, diallyl disulfide, and diallyl trisulfide. Because the intake of garlic or therapeutically active substance such as allicin from garlic, induces immunostimulation and possess strong antitumor effects concomitant with apoptosis of tumors that can in turn induces a programmed cell death of human prostatic and bladder tumor cells. This invention claims that garlic and / or garlic extracts possess very effective therapeutic substances not only to treat human prostate and bladder cancers to extend life span of patients, but also to suppress or prevent bladder and prostate gland cancers.
Owner:CHEON JUN +4

Controlled-release hydrogen sulfide donor as well as preparation method and application thereof

The invention relates to a controlled-release hydrogen sulfide donor. The donor is obtained by reacting diallyl trisulfide with an ordered mesoporous silicon dioxide nanoparticle materials. The invention also provides a preparation method and application of the hydrogen sulfide donor. The controlled-release hydrogen sulfide donor is capable of slowly releasing medium-concentration hydrogen sulfide, can be regulated by use of glutathione and has no obvious cytotoxicity; as a result, the controlled-release hydrogen sulfide donor is an ideal hydrogen sulfide donor for in-vivo and in-vitro experiments and clinical application.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV

Liquid environment-friendly heating water anti-theft agent and preparation method thereof

The invention relates to a liquid environment-friendly heating water anti-theft agent and a preparation method thereof. The heating water anti-theft agent comprises the components based on the weight ratio: 65-94.4% of diallyl disulfide, 0.3-15% of diallyl trisulfide, 0.1-10% of propene thiol, 2-3% of boiler corrosion inhibitor, 3-5% of boiler scale inhibitor and 0.2-2% of amidosulphuric acid; the components are weighed according to the mixture ratio and evenly mixed together. The invention is beneficial to preventing residents from illegally stealing the water used for heating, so as to effectively reduce the heating cost of heating enterprises, ensure the boiler plant to have safe operation, and be beneficial to prolonging the service life of the boiler.
Owner:刘占省

Composition used for treating AIDS and associated diseases and preparation method thereof

The invention relates to a pharmaceutical composition, in particular to a composition used for treating AIDS. The composition for treating AIDS and associated diseases comprises the following components (wt%): 30-40% of diallyl disulfide (DADS), about 40-50% of diallyl trisulfide (DATS), namely allicin, and 10-30% of allyl methyl disulfide. A preparation method of the composition used for treating AIDS and associated diseases comprises the following steps of: selecting big and plump garlic; peeling off, washing and mashing the same; putting the garlic spread in a distilling device, adding distilled water or pure water; distilling, collecting volatile oil in a brown glass bottle; preserving at 0-5 DEG C. the composition of the invention can act on HIV-1 virus and has comparatively good effect on AIDS and associated diseases.
Owner:沈德铭 +1

Environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and production technology and use method thereof

The invention provides an environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and a production technology and a use method thereof. The fertilizer is a neutral or weakly acidic fertilizer, and contains a diallyl disulfide and diallyl trisulfide mixture. The pH value of a saturated aqueous solution of the fertilizer can be 5-7, and preferably 6.5-7. The fertilizer can have the following one or more characteristics: 1, a compound fertilizer or a composite fertilizer; 2, a slow release fertilizer or a controlled release fertilizer; 3, an organic fertilizer or an inorganic fertilizer or an organic-inorganic compound fertilizer; 4, urea, a urea-ammonium mixed nitrogen fertilizer and polypeptide urea; 5, monoammonium phosphate and diammonium phosphate; and 6, potassium chloride and potassium sulfate. The fertilizer can provide crop nutrients, effectively purifies soil and control the diseases and insect pests of crops, and diallyl disulfide and diallyl trisulfide are from garlic extracts, are most safe biological pesticides proved in the laboratory at present, have no toxic side effects, no drug residual and no drug resistance, and are best additives substituting antibiotics to produce nuisance free products.
Owner:朱崇靖

Feed capable of reducing the cholesterol content in duck eggs

InactiveCN103598423AReduce egg yolk cholesterol contentReduce concentrationAnimal feeding stuffYolkAnimal science
The invention discloses feed capable of reducing the cholesterol content in duck eggs. The feed is prepared by adding 200-800 mg / kg of garlic oil to complete-feed basic ration, wherein the main components of the garlic oil are diallyl disulfide and diallyl trisulfide, and the content of the garlic oil is larger than 10.5%. The feed provided by the invention can significantly reduce the feed-egg ratio and reduce deposition of the cholesterol in egg yolks, and therefore the feed provided by the invention has significant practical meaning for development of low-cholesterol health-care duck eggs and for sustainable development of the whole laying-duck industry.
Owner:HUNAN AGRICULTURAL UNIV

Allitride composition and method thereof for preparing drop capable of treating nasal cavity microbial infection and use thereof

InactiveCN101390849AOvercoming the defects of poor treatment effectGood effectOrganic active ingredientsRespiratory disorderNasal cavityAdditive ingredient
The invention relates to a medicine for the treatment of microbial infection, in particular to allitridon drops used for the treatment of microbial infection. The allitridon drops mainly contain the following ingredients, 0.8-4ml of diallyl trisulfide, tween-80 with the amount of dissolving the diallyl trisulfide, 7-9g of NaCl, 1000ml of distilled water. The allitridon drops have the advantages of being applicable to the treatment of microbial infection, good treatment effects and low cost.
Owner:沈德铭

Environment-friendly automobile wool heavy filth cleaning agent and preparation method thereof

The invention provides an environment-friendly automobile wool heavy filth cleaning agent and a preparation method thereof. The environment-friendly automobile wool heavy filth cleaning agent comprises the following components in parts by weight: 10-35 parts of polyvinylpyrrolidone, 6-25 parts of sodium oleate, 5-30 parts of starch, 1-5 parts of maleic anhydride, 1-9 parts of fatty acid imidazoline borate, 3-10 parts of borax, 2-8 parts of diallyl trisulfide, 1-7 parts of methylene dithiocyanate, 5-10 parts of potassium hydroxide, 8-12 parts of silicone oil, 5-15 parts of oleic acid, 3-10 parts of orange oil, 2-4 parts of strawberry powder, 1-5 parts of citric acid and 30-120 parts of water. The environment-friendly automobile wool heavy filth cleaning agent provided by the invention has the benefits that the environment-friendly automobile wool heavy filth cleaning agent can directly clean wool fabric in clear water and enable the cleaning of the wool fabric to be more convenient; the deoiling and filth-removing effect of the cleaning agent is better than the traditional dry cleaning effect; the environment-friendly automobile wool heavy filth cleaning agent has ultra-strong bactericidal and deodorant effects.
Owner:TIANJIN YICHENG LONGDA ENVIRONMENTAL PROTECTION TECH DEV

Alliin-based antibiotic-replacement feed synbiotic composition and preparation method thereof

The invention discloses an alliin-based antibiotic-replacement feed synbiotic composition, and relates to an alliin-based antibiotic-replacement feed synbiotic composition and a preparation method thereof. The allicin is allicin which is obtained through natural fermentation treatment and contains stable sulfide components, and comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS). Theprobiotics is selected from one or combination from lactic acid bacteria and bacillus licheniformis; bacillus subtilis, bifidobacterium bifidum, enterococcus faecalis, enterococcus faecium, lactobacillus acidophilus, lactobacillus casei, lactobacillus plantarum, pediococcus pentosaceus, the invention discloses rhodopseudomonas palustris. The composition is one or a combination of more of bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, bifidobacterium animalis, bifidobacterium adolescentis, streptococcus thermophilus, lactobacillus reuteri, aspergillus niger, aspergillus oryzae, bacillus tarda, bacillus pumilus, lactobacillus cellobiosus, lactobacillus fermentum, lactobacillus bulgaricus, lactobacillus buchneri and bacillus laterosporus. The method is used for special breeding environments with aseptic requirements, improving the water source environment of farms and the like.
Owner:山东健为生物科技有限公司

Extraction of garlic volatile oil

The invention discloses a preparation method of garlic oil, which comprises the steps of crushing garlic into different particle sizes according to the different contents of diallyl trisulfide and diallyl disulfide in the required garlic oil, and adding water to keep warm for enzymolysis , Steam distillation extracts volatile oil, dehydrates volatile oil with water, and obtains garlic oil. In the preparation process of garlic oil, the present invention can increase the content of diallyl trisulfide in the obtained garlic oil, or increase the content of diallyl disulfide, or The contents of the two are relatively in the middle, so as to meet the needs of medical products or health products for different treatments.
Owner:INST OF BASIC THEORY OF TCM CHINA ACADEMY OF CHINESE MEDICAL SCI

Odorless garlic ferment and preparation method thereof

The invention discloses odorless garlic ferment, and relates to odorless garlic enzyme and a preparation method thereof. The odorless garlic ferment is characterized by comprising amino acids and garlic polysaccharides which are obtained by fermenting and decomposing proteins contained in allicin and garlic, wherein the allicin comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS), andthe allicin is stable allicin which is obtained through natural fermentation treatment and contains sulfide components. The method disclosed by the invention is simple in process, the produced odorless garlic ferment is particularly stable, can be stored for more than two years or even longer for a long time, is lower in cost and is easy for industrial popularization. Supernatant stored after standing for a long time can become acidic sterile liquid, can be exposed to an open environment for a long time, and can be used in special environments with sterile requirements.
Owner:山东健为生物科技有限公司

Natural-allicin-containing antibiotic-replacing feed and preparation method thereof

The invention relates to the technical field of feed processing, in particular to a natural-allicin-containing antibiotic-replacing feed and a preparation method thereof. Raw materials containing natural allicin comprise allicin, protein contained in garlic, and amino acid and garlic polysaccharide obtained through decomposition after fermentation, the allicin comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS), and the allicin is stable allicin which is obtained through natural fermentation treatment and contains sulfide components. Volatilization and decomposition cannot easilyoccur; acceptance and popularization are facilitated; and no drug dependence is generated, and no residues are left. According to the natural-allicin-containing antibiotic-replacing feed, no antibiotics areadded in the breeding process, the growth promoting effect of antibiotics can be replaced, and the feed has the effects of mold prevention, sterilization and the like and is not prone to being contaminated in the transportation and storage processes; the feed is simple in process, wide in application range and suitable for most cultured animals; and the feed can be stored for more than two years or even longer, and is low in cost and easy to popularize industrially.
Owner:山东健为生物科技有限公司

Sustained-release composition, method for fabricating, and use thereof

A sustained-release composition is provided in the present disclosure for producing a therapeutic gas, such as hydrogen sulfide or hydrogen. The sustained-release composition includes a precursor and a carrier. The precursor is diallyl trisulfide or magnesium, and the carrier includes a poly lactic-co-glycolic acid copolymer for carrying the precursor with an efficient amount.
Owner:NATIONAL TSING HUA UNIVERSITY

Preparation method of traditional Chinese medicine additive for pig feed

The invention discloses a preparation method of a traditional Chinese medicine additive for a pig feed. The preparation method comprises the following steps of S1, selecting materials; S2, preparing amixture A; S3, performing crushing for the first time; S4, preparing a mixture B; S5, performing crushing for the second time; and S6, preparing the traditional Chinese medicine additive of the pig feed. According to the preparation method of the traditional Chinese medicine additive for the pig feed disclosed by the invention, rich physiological active substances can be provided to have the effects of stimulating the growth of pigs, preventing and treating diseases, guaranteeing health and the like, so that the growth of the pigs can be promoted, and the yield and the quality of pork can beincreased. According to the preparation method of the traditional Chinese medicine additive for the pig feed, diallyl trisulfide is added at the same time, and the diallyl trisulfide can have the restraining effects in vitro on blastomyces albicans, red cryptococcus, cryptococcus and the like. Besides, the attack rate of cardiovascular diseases can be reduced by reducing serum cholesterol, preventing platelet aggregation and increasing fibrinogen dissolution.
Owner:嵩县金佛坪农业科技有限公司

Application of diallyl trisulfide to preparation of preparation for inhibiting pseudomonas aeruginosa secretion systems

The invention discloses application of diallyl trisulfide to preparation of a preparation for inhibiting pseudomonas aeruginosa secretion systems. The invention finds that the diallyl trisulfide slightly inhibits the growth of a pseudomonas aeruginosa PAO1 strain, but can obviously inhibit the expression of key genes in II-type and VI-type secretion systems of the pseudomonas aeruginosa PAO1 strain, and inhibit the function of the secretion systems of the pseudomonas aeruginosa PAO1 strain and the secretion of virulence factors of the pseudomonas aeruginosa PAO1 strain. Therefore, the diallyl trisulfide can be applied to preparation of the preparation for inhibiting the pseudomonas aeruginosa secretion systems for controlling the toxicity and pathogenicity of the pseudomonas aeruginosa.
Owner:GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY

A kind of plant type vapor phase copper corrosion inhibitor and preparation method thereof

InactiveCN105200436BImprove pungent tasteGood corrosion inhibition effectCopperAzocane
The invention discloses a plant type vapor phase copper corrosion inhibitor and a preparation method thereof. The volatile matter of the corrosion inhibitor contains 5wt%-20wt% of dipropenyl trisulfide, 2wt%-10wt% of dipropenyl disulfide, 2wt%-10wt% of 1-oxygen-4,6-disulfide Azoctane‑5‑thione and 30wt%‑50wt% eucalyptol. It is a mixture of garlic extract and bay leaf extract in a weight ratio of 3:1. The plant-type gas-phase copper corrosion inhibitor provided by the invention has obvious corrosion inhibition effect, simple preparation method, safety, non-toxicity and environmental friendliness.
Owner:HUAZHONG UNIV OF SCI & TECH

Application of diallyl trisulfide to food allergies

The invention discloses application of diallyl trisulfide to food allergies, and belongs to the technical field of medicine. The invention provides new application of diallyl trisulfide to relief and treatment of food allergies. Animal experiments prove that the diallyl trisulfide can reduce the incidence rate of diarrhea of food allergy mice, relieve the decrease of the rectal temperature, reduce the serum OVA specific IgE level and mast cell protease level, has a relieving effect on jejunum tissue damage, can be used for preparing a medicine, a pharmaceutical composition, a functional food or a formula food for special medical purposes for treating food allergies, and has a wide application prospect.
Owner:JIANGNAN UNIV

Hydrogen sulphide compounds capable of stimulating h2s production in a pregnant subject

The present application relates to the use of a H2S-producing compound for the treatment of preeclampsia or fetal growth limitation, wherein the H2S-producing compound is ACS 14, ACS 83, ACS 84, ACS 85, ACS 86, diallyl trisulfide, S-diclofenac, GSH hydropersulfate, SG1002, ADT-OH, TBZ, thioglycine, 1-thiolysine, 1-thiovaline or a salt thereof, H2S-latanoprost, H2S-sildenafil or H2S-L-dopa.
Owner:MIRZYME THERAPEUTICS LTD

A slow-release hydrogen sulfide donor and its preparation method and application

The invention relates to a controlled-release hydrogen sulfide donor. The donor is obtained by reacting diallyl trisulfide with an ordered mesoporous silicon dioxide nanoparticle materials. The invention also provides a preparation method and application of the hydrogen sulfide donor. The controlled-release hydrogen sulfide donor is capable of slowly releasing medium-concentration hydrogen sulfide, can be regulated by use of glutathione and has no obvious cytotoxicity; as a result, the controlled-release hydrogen sulfide donor is an ideal hydrogen sulfide donor for in-vivo and in-vitro experiments and clinical application.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV

Application of garlic-derived substances in treatment and/or prevention of psoriasis

PendingCN112535680ARepair skin lesionsInhibit erythemaOrganic active ingredientsCarbon-sulfur lyasesAlliinaseEnzyme catalysis
The invention relates to alliin derived from garlic, allicin as an enzyme catalytic product of alliin, diallyl monosulfide, diallyl disulfide, diallyl trisulfide, dehydrated garlic, dehydrated garlicwith inactivated alliinase, and the like, which are used for preventing and / or treating psoriasis.
Owner:新疆胡蒜研究院(有限公司)

A kind of deworming and insecticidal, bacteriostatic and bactericidal environment-friendly fertilizer and its production process and application method

The invention provides an environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and a production technology and a use method thereof. The fertilizer is a neutral or weakly acidic fertilizer, and contains a diallyl disulfide and diallyl trisulfide mixture. The pH value of a saturated aqueous solution of the fertilizer can be 5-7, and preferably 6.5-7. The fertilizer can have the following one or more characteristics: 1, a compound fertilizer or a composite fertilizer; 2, a slow release fertilizer or a controlled release fertilizer; 3, an organic fertilizer or an inorganic fertilizer or an organic-inorganic compound fertilizer; 4, urea, a urea-ammonium mixed nitrogen fertilizer and polypeptide urea; 5, monoammonium phosphate and diammonium phosphate; and 6, potassium chloride and potassium sulfate. The fertilizer can provide crop nutrients, effectively purifies soil and control the diseases and insect pests of crops, and diallyl disulfide and diallyl trisulfide are from garlic extracts, are most safe biological pesticides proved in the laboratory at present, have no toxic side effects, no drug residual and no drug resistance, and are best additives substituting antibiotics to produce nuisance free products.
Owner:朱崇靖

Novel method for synthesizing allicin

The invention discloses a novel method for synthesizing allicin, which is technically characterized in that tetrabutylammonium bromide is used as a phase transfer catalyst for synthesizing diallyl trisulfide, so that the reaction time is shortened, and the yield is improved. The method has the advantages that, a problem in the prior art that the allyl chloride-sodium thiosulfate-sodium sulfide method is mainly adopted for synthesis in the industry at present, but the yield of the two-phase reaction is low due to the fact that the reactant allyl chloride is insoluble in water is solved. According to the method, tetrabutylammonium bromide, TBAI for short, is used as the phase transfer catalyst to synthesize diallyl trisulfide, so that the reaction time is shortened, the yield is increased, and the reaction equation is shown in the specification.
Owner:JIANGSU QINGJIANG PHARMA

A kind of preparation method of hydrogen sulfide sustained-release gel and its application in the preparation of diabetic skin ulcer treatment medicine

The invention discloses a preparation method of hydrogen sulfide sustained-release gel and its application in the preparation of medicines for treating diabetic skin ulcers, including preparing cyclodextrin inclusion compound DATS@CD containing diallyl trisulfide respectively DATS@CD‑Alginate Gel and CaCl with Glutathione 2 ‑Chitosan gel; DATS@CD‑sodium alginate gel and CaCl prepared by the present invention 2 ‑Chitosan gel compound can slow down the reaction between DATS and GSH, realize H 2 For the purpose of sustained release of S, at the same time, the joint application of DATS@CD‑sodium alginate gel and CaCl 2 ‑Chitosan gel can effectively promote diabetic skin wound healing.
Owner:XUZHOU MEDICAL UNIV

Processing method for garlic oil

The invention discloses a processing method of garlic oil, which uses allyl chloride as a raw material, and undergoes vulcanization, condensation, physical layering and separation to prepare garlic oil with dipropenyl trisulfide as the main component; the processing method provided by the invention No need to use organic solvents such as toluene and ether, the processing technology is simple, the operation is convenient, and the content of diallyl trisulfide in the obtained product is ≥ 50%, which is suitable for large-scale popularization and application.
Owner:宜兴市天石饲料有限公司

Method for analyzing diallyl trisulfide in food industry wastewater

The invention relates to the field of compound analysis, particularly to a method for analyzing diallyl trisulfide in food industry wastewater. According to the method, the pH value of to-be-detectedfood industrial wastewater is adjusted, a certain amount of methanol is added, and the sample is fed to a solid-phase extraction column at a certain flow rate, so that diallyl trisulfide in the to-be-detected sample can be effectively adsorbed and enriched by the solid-phase extraction column; and after the solid-phase extraction column is pumped to be dry, most impurities in the to-be-detected wastewater are removed, and at the moment, a n-hexane or n-hexane-dichloromethane mixed solvent flows through the solid-phase extraction column, so ,hat diallyl trisulfide can be efficiently eluted, primary separation of diallyl trisulfide in food industry wastewater with complex components is realized, the preliminarily separated sample can be used for subsequent detection, and quantitative analysis of diallyl trisulfide in food industry wastewater with complex components and numerous interference factors is realized.
Owner:广电计量检测(合肥)有限公司

Environment-friendly hand sanitizer

The invention provides an environment-friendly hand sanitizer. The environment-friendly hand sanitizer is prepared from the following components in parts by weight: 6 to 12 parts of plant ash, 0.1 to0.4 part of surfactant, 0.5 to 0.8 part of lemon essence, 4 to 8 parts of alcohol, 3 to 6 parts of glycerin, 8 to 18 parts of deionized water, and 0.1 to 0.2 part of diallyl trisulfide. The environment-friendly hand sanitizer has the advantages that the easily-degradable effect is realized, and the pollution to a water body is favorably reduced.
Owner:FOSHAN WASEDA INFORMATION CONSULTATION CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products