30 results about "Allyl trisulfide" patented technology

The invention relates to an effective part of Chinese drug and relative application, wherein, the effective part is a compound whose main components are allyl disulfide (DADS) and methacrylic trisulfide (MATS), without diallyl trisulfide (DATS) as allicin, while the effective part is significant different from garlic oil in quality and quantity, which is separated and extracted from garlic oil. The effective part has the functions as antibiosis and antiviral (as anti-AIDS and anti-herpesvirus) outside the body, and the anti-tumor function (as anti-leukemia), and anti-thrombus) function. Compared with allicin, the invention has high stability and low side effect, while the effective part can be used to prepare the drug for treating virus, bacterial, tumor and thrombus, with wide clinic application.

This invention is concerned with clinical investigation of therapeutic effects of garlic extracts containing allicin, diallyl disulfide, and diallyl trisulfide. Because the intake of garlic or therapeutically active substance such as allicin from garlic, induces immunostimulation and possess strong antitumor effects concomitant with apoptosis of tumors that can in turn induces a programmed cell death of human prostatic and bladder tumor cells. This invention claims that garlic and / or garlic extracts possess very effective therapeutic substances not only to treat human prostate and bladder cancers to extend life span of patients, but also to suppress or prevent bladder and prostate gland cancers.

The invention relates to a controlled-release hydrogen sulfide donor. The donor is obtained by reacting diallyl trisulfide with an ordered mesoporous silicon dioxide nanoparticle materials. The invention also provides a preparation method and application of the hydrogen sulfide donor. The controlled-release hydrogen sulfide donor is capable of slowly releasing medium-concentration hydrogen sulfide, can be regulated by use of glutathione and has no obvious cytotoxicity; as a result, the controlled-release hydrogen sulfide donor is an ideal hydrogen sulfide donor for in-vivo and in-vitro experiments and clinical application.

The invention relates to a medicine for the treatment of microbial infection, in particular to allitridon drops used for the treatment of microbial infection. The allitridon drops mainly contain the following ingredients, 0.8-4ml of diallyl trisulfide, tween-80 with the amount of dissolving the diallyl trisulfide, 7-9g of NaCl, 1000ml of distilled water. The allitridon drops have the advantages of being applicable to the treatment of microbial infection, good treatment effects and low cost.

The invention discloses an alliin-based antibiotic-replacement feed synbiotic composition, and relates to an alliin-based antibiotic-replacement feed synbiotic composition and a preparation method thereof. The allicin is allicin which is obtained through natural fermentation treatment and contains stable sulfide components, and comprises diallyl disulfide (DADS) and diallyl trisulfide (DATS). Theprobiotics is selected from one or combination from lactic acid bacteria and bacillus licheniformis; bacillus subtilis, bifidobacterium bifidum, enterococcus faecalis, enterococcus faecium, lactobacillus acidophilus, lactobacillus casei, lactobacillus plantarum, pediococcus pentosaceus, the invention discloses rhodopseudomonas palustris. The composition is one or a combination of more of bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, bifidobacterium animalis, bifidobacterium adolescentis, streptococcus thermophilus, lactobacillus reuteri, aspergillus niger, aspergillus oryzae, bacillus tarda, bacillus pumilus, lactobacillus cellobiosus, lactobacillus fermentum, lactobacillus bulgaricus, lactobacillus buchneri and bacillus laterosporus. The method is used for special breeding environments with aseptic requirements, improving the water source environment of farms and the like.

The invention discloses a preparation method of garlic oil, which comprises the steps of crushing garlic into different particle sizes according to the different contents of diallyl trisulfide and diallyl disulfide in the required garlic oil, and adding water to keep warm for enzymolysis , Steam distillation extracts volatile oil, dehydrates volatile oil with water, and obtains garlic oil. In the preparation process of garlic oil, the present invention can increase the content of diallyl trisulfide in the obtained garlic oil, or increase the content of diallyl disulfide, or The contents of the two are relatively in the middle, so as to meet the needs of medical products or health products for different treatments.

The invention discloses a preparation method of a traditional Chinese medicine additive for a pig feed. The preparation method comprises the following steps of S1, selecting materials; S2, preparing amixture A; S3, performing crushing for the first time; S4, preparing a mixture B; S5, performing crushing for the second time; and S6, preparing the traditional Chinese medicine additive of the pig feed. According to the preparation method of the traditional Chinese medicine additive for the pig feed disclosed by the invention, rich physiological active substances can be provided to have the effects of stimulating the growth of pigs, preventing and treating diseases, guaranteeing health and the like, so that the growth of the pigs can be promoted, and the yield and the quality of pork can beincreased. According to the preparation method of the traditional Chinese medicine additive for the pig feed, diallyl trisulfide is added at the same time, and the diallyl trisulfide can have the restraining effects in vitro on blastomyces albicans, red cryptococcus, cryptococcus and the like. Besides, the attack rate of cardiovascular diseases can be reduced by reducing serum cholesterol, preventing platelet aggregation and increasing fibrinogen dissolution.

The invention discloses application of diallyl trisulfide to preparation of a preparation for inhibiting pseudomonas aeruginosa secretion systems. The invention finds that the diallyl trisulfide slightly inhibits the growth of a pseudomonas aeruginosa PAO1 strain, but can obviously inhibit the expression of key genes in II-type and VI-type secretion systems of the pseudomonas aeruginosa PAO1 strain, and inhibit the function of the secretion systems of the pseudomonas aeruginosa PAO1 strain and the secretion of virulence factors of the pseudomonas aeruginosa PAO1 strain. Therefore, the diallyl trisulfide can be applied to preparation of the preparation for inhibiting the pseudomonas aeruginosa secretion systems for controlling the toxicity and pathogenicity of the pseudomonas aeruginosa.

The invention discloses a plant type vapor phase copper corrosion inhibitor and a preparation method thereof. The volatile matter of the corrosion inhibitor contains 5wt%-20wt% of dipropenyl trisulfide, 2wt%-10wt% of dipropenyl disulfide, 2wt%-10wt% of 1-oxygen-4,6-disulfide Azoctane‑5‑thione and 30wt%‑50wt% eucalyptol. It is a mixture of garlic extract and bay leaf extract in a weight ratio of 3:1. The plant-type gas-phase copper corrosion inhibitor provided by the invention has obvious corrosion inhibition effect, simple preparation method, safety, non-toxicity and environmental friendliness.

The present application relates to the use of a H2S-producing compound for the treatment of preeclampsia or fetal growth limitation, wherein the H2S-producing compound is ACS 14, ACS 83, ACS 84, ACS 85, ACS 86, diallyl trisulfide, S-diclofenac, GSH hydropersulfate, SG1002, ADT-OH, TBZ, thioglycine, 1-thiolysine, 1-thiovaline or a salt thereof, H2S-latanoprost, H2S-sildenafil or H2S-L-dopa.

The invention relates to a controlled-release hydrogen sulfide donor. The donor is obtained by reacting diallyl trisulfide with an ordered mesoporous silicon dioxide nanoparticle materials. The invention also provides a preparation method and application of the hydrogen sulfide donor. The controlled-release hydrogen sulfide donor is capable of slowly releasing medium-concentration hydrogen sulfide, can be regulated by use of glutathione and has no obvious cytotoxicity; as a result, the controlled-release hydrogen sulfide donor is an ideal hydrogen sulfide donor for in-vivo and in-vitro experiments and clinical application.

The invention provides an environmentally friendly fertilizer for pest dispelling, pest killing, bacterium inhibiting and bacterium killing, and a production technology and a use method thereof. The fertilizer is a neutral or weakly acidic fertilizer, and contains a diallyl disulfide and diallyl trisulfide mixture. The pH value of a saturated aqueous solution of the fertilizer can be 5-7, and preferably 6.5-7. The fertilizer can have the following one or more characteristics: 1, a compound fertilizer or a composite fertilizer; 2, a slow release fertilizer or a controlled release fertilizer; 3, an organic fertilizer or an inorganic fertilizer or an organic-inorganic compound fertilizer; 4, urea, a urea-ammonium mixed nitrogen fertilizer and polypeptide urea; 5, monoammonium phosphate and diammonium phosphate; and 6, potassium chloride and potassium sulfate. The fertilizer can provide crop nutrients, effectively purifies soil and control the diseases and insect pests of crops, and diallyl disulfide and diallyl trisulfide are from garlic extracts, are most safe biological pesticides proved in the laboratory at present, have no toxic side effects, no drug residual and no drug resistance, and are best additives substituting antibiotics to produce nuisance free products.

A sustained-release composition is provided in the present disclosure for producing a therapeutic gas, such as hydrogen sulfide or hydrogen. The sustained-release composition includes a precursor and a carrier. The precursor is diallyl trisulfide or magnesium, and the carrier includes a poly lactic-co-glycolic acid copolymer for carrying the precursor with an efficient amount.

The invention discloses a preparation method of hydrogen sulfide sustained-release gel and its application in the preparation of medicines for treating diabetic skin ulcers, including preparing cyclodextrin inclusion compound DATS@CD containing diallyl trisulfide respectively DATS@CD‑Alginate Gel and CaCl with Glutathione 2 ‑Chitosan gel; DATS@CD‑sodium alginate gel and CaCl prepared by the present invention 2 ‑Chitosan gel compound can slow down the reaction between DATS and GSH, realize H 2 For the purpose of sustained release of S, at the same time, the joint application of DATS@CD‑sodium alginate gel and CaCl 2 ‑Chitosan gel can effectively promote diabetic skin wound healing.

The invention relates to the field of compound analysis, particularly to a method for analyzing diallyl trisulfide in food industry wastewater. According to the method, the pH value of to-be-detectedfood industrial wastewater is adjusted, a certain amount of methanol is added, and the sample is fed to a solid-phase extraction column at a certain flow rate, so that diallyl trisulfide in the to-be-detected sample can be effectively adsorbed and enriched by the solid-phase extraction column; and after the solid-phase extraction column is pumped to be dry, most impurities in the to-be-detected wastewater are removed, and at the moment, a n-hexane or n-hexane-dichloromethane mixed solvent flows through the solid-phase extraction column, so ,hat diallyl trisulfide can be efficiently eluted, primary separation of diallyl trisulfide in food industry wastewater with complex components is realized, the preliminarily separated sample can be used for subsequent detection, and quantitative analysis of diallyl trisulfide in food industry wastewater with complex components and numerous interference factors is realized.