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Valid target of garlic oil and the application in preparing many kinds of medicine

A technology of effective parts and garlic oil, applied in the field of effective parts of traditional Chinese medicine, can solve problems such as poor stability and high irritation

Inactive Publication Date: 2007-09-26
沈联慈 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Garlic oil has a wide range of effects and few side effects, and is still a research hotspot at home and abroad. However, due to its poor stability and strong irritation, there is no antibacterial, anti-virus, anti-tumor and treatment of cardiovascular diseases related to garlic oil. new drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Recipe: garlic oil 0.3%-5%

[0026] Edible oil (soy oil or corn oil) 95%-99%

[0027] Antioxidant

[0028] Aromatic deodorant

[0029] Preparation method: Prepare gastric-soluble soft capsules (capsules) or enteric-coated capsules according to the conventional preparation method.

[0030] Uses: Used to treat bacterial or fungal infections of the respiratory tract, gastrointestinal tract, and urinary system, as well as HIV or herpes virus infections, and reduce blood lipids, anti-thrombosis, and reduce coronary atherosclerosis.

Embodiment 2

[0032] Recipe: garlic oil 0.5% -1.5%

[0033] Cyclodextrin 5%-30%

[0034] Solid filler

[0035] Preparation method: The garlic oil essence is made into cyclodextrin inclusion compound by ultrasonic method or stirring method, and then it is mixed with solid filler in an appropriate amount and filled into hard capsules.

[0036] Uses: Used to treat bacterial or fungal infections of the respiratory tract, gastrointestinal tract, and urinary system, as well as HIV or herpes virus infections, and reduce blood lipids, anti-thrombosis, and reduce coronary atherosclerosis.

Embodiment 3

[0038] Recipe: garlic oil 0.1%-2%

[0039] Emulsifier 0.25%-10%

[0040] Co-emulsifier 20%-90%

[0041] Antioxidant

[0042] Flavoring agent

[0043] Aroma deodorant

[0044] Distilled water to 100ml

[0045] Preparation method: Mix the above components into glass bottles to prepare oral liquid.

[0046] Usage: Dilute the oral liquid before use.

[0047] Uses: Used to treat bacterial or fungal infections of the respiratory tract, gastrointestinal tract, and urinary system, as well as HIV or herpes virus infections, and reduce blood lipids, anti-thrombosis, and reduce coronary atherosclerosis.

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PUM

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Abstract

The invention relates to an effective part of Chinese drug and relative application, wherein, the effective part is a compound whose main components are allyl disulfide (DADS) and methacrylic trisulfide (MATS), without diallyl trisulfide (DATS) as allicin, while the effective part is significant different from garlic oil in quality and quantity, which is separated and extracted from garlic oil. The effective part has the functions as antibiosis and antiviral (as anti-AIDS and anti-herpesvirus) outside the body, and the anti-tumor function (as anti-leukemia), and anti-thrombus) function. Compared with allicin, the invention has high stability and low side effect, while the effective part can be used to prepare the drug for treating virus, bacterial, tumor and thrombus, with wide clinic application.

Description

Technical field [0001] The present invention relates to effective parts of traditional Chinese medicine and uses thereof. Background technique [0002] Garlic oil is a kind of volatile oil obtained from garlic (the underground bulb of the Allium. Sativum L. plant of the Liliaceae) after being crushed, fermented, and distilled with water. Garlic oil is analyzed by gas chromatography and contains more than 30 components, mostly allyl. Sulfides, among which the high content is diallyl trisulfide, the English abbreviation is DATS, (molecular formula C 6 H 10 S 3 , Molecular weight 168, chemical formula H 2 C=CH-CH 2 -S-S-S-CH 2 -CH=CH 2 ), which occupies 40-65% of garlic oil, and can now be synthesized artificially, named allicin. Others also contain diallyl disulfide DADS, methallyl trisulfide MATS and so on. A large number of domestic and foreign studies have shown that allicin and garlic oil have a variety of biological activities, have antibacterial effects on a variety of pathog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K31/105A61P35/00A61P31/04A61P31/10A61P31/12A61P31/18A61P31/22A61P7/02A61P9/10
CPCY02A50/30
Inventor 沈联慈冯俊华
Owner 沈联慈
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