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Method using enteric-coated etidronate for treating calcification, hypercalcaemia, and calcinosis of the brain and other organs

a technology of enteric coating and etidronate, which is applied in the field of applying drugs to treat diseases caused by calcinosis, can solve the problems of human infection and human infection, and achieve the effect of minimizing the adverse effects of an oversupply of calcium and potent binders of free calcium

Active Publication Date: 2019-02-21
ZY YTHERAPEUTICS LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes an oral drug that contains a safe and effective medication called bisphosphonate, which is designed to release in the lower gastrointestinal tract to reduce damage to the upper gastrointestinal tract. The drug is also formulated to prevent the medicine from causing ulceration or perforation in the stomach and esophagus. The technical effect of the patent is to provide a safer and effective treatment for diseases associated with calcium deposits, such as Sturge-Weber Syndrome, while minimizing the risk of ulceration and perforation.

Problems solved by technology

Humans become infected with T. saginata when they consume beef which has not been adequately cooked.
Humans can also become infected with T. solium eggs by ingesting contaminated food or water (human cysticercosis) or as a result of poor hygiene.
When cysts develop in the brain, neurocysticercosis may result.
Symptoms include epilepsy, severe headache and blindness, and, if left untreated, it can be fatal.

Method used

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  • Method using enteric-coated etidronate for treating calcification, hypercalcaemia, and calcinosis of the brain and other organs
  • Method using enteric-coated etidronate for treating calcification, hypercalcaemia, and calcinosis of the brain and other organs
  • Method using enteric-coated etidronate for treating calcification, hypercalcaemia, and calcinosis of the brain and other organs

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Embodiment Construction

[0060]Reference now will be made in detail to embodiments of the invention, one or more examples of which are illustrated more fully in the drawings. Each example is provided by way of explanation of the invention, not limitation of the invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. In fact, it will be apparent to those skilled in the art that various modifications and variations can be made in the present invention, fully described in the claims, without departing from the scope or spirit of the invention. For instance, features illustrated or described as part of one embodiment can be used with another embodiment and such variations come within the scope of the appended claims and their equivalents.

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Abstract

Among other things, compositions, kits, and methods for epilepsy therapy using a process for treating calcinosis manifested in Neurocysticercosis, Tuberous Sclerosis Complex, and Sturge-Weber Syndrome; an automated platform for real-time diagnosis and treatment of calcinosis comprising a computer-implemented method for using predictive analytics for administering a novel drug, Kamini™, to human patients generated at least in part from information that has been accumulated automatically from on-line resources.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit of U.S. Provisional Patent Application No. 62 / 548,344, filed on Aug. 21, 2017, which is incorporated by reference herein in its entirety.NOTICE OF COPYRIGHTS, TRADEMARKS, AND TRADE DRESS[0002]A portion of the disclosure of this patent document contains material that is subject to copyright protection. This patent document may show and / or describe matter that is or may become trade dress of the owner(s). The copyright and trade dress owners have no objection to the facsimile reproduction by anyone of the patent disclosure as it appears in the Patent and Trademark Office patent files or records, but otherwise reserves all copyrights and trade dress rights whatsoever. Kamini™ is an enteric-coated disodium etidronate optimized by Zy Therapeutics, LLC for treating neurological calcifications and other disease-producing calcifications.TECHNICAL FIELD[0003]The present invention, fully described in the claims, r...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K9/28A61K9/00A61K31/663A61P25/08G16H70/20G16H20/10A61B5/00G16H70/40A61B6/00G06F19/28
CPCA61K9/2846A61K9/0053A61K31/663A61P25/08G16B50/00A61B5/4848G16H70/40A61B6/501G16H70/20G16H20/10A61K9/0056A61K9/4816A61K9/4891A61K9/5026A61B5/002A61B5/021A61B5/14546A61B5/4839G16H50/20G16H50/70
Inventor HILL, BRYAN ALANMCCARTY, JOHN STEPHANLOEB, JEFFREY ARLIN
Owner ZY YTHERAPEUTICS LLC
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