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Method for manufacturing nanoparticle array, surface plasmon resonance-based sensor and method for analyzing using same

a surface plasmon resonance and nanoparticle technology, applied in the field of sensor technology, can solve the problems of affecting the quality of nanoparticle arrays, and limiting the substrate materials for nano-island formation, etc., and achieves enhanced detection sensitivity, easy to amplify the measurement sensitivity, and cost-effective

Inactive Publication Date: 2019-11-07
PLEXENSE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention offers a cost-effective way to make nanoparticle arrays by dipping a substrate into a mixed solution of an ionic binder and conductive nanoparticles, followed by applying an electric field outside. Additionally, it provides a sensor with enhanced detection sensitivity by adapting the high metal nanoparticle density sensor for SPR or LSPR mode-based spectroscopic analysis. Furthermore, multiple stacking of the stated sensor can amplify the measurement sensitivity by increasing the conductive metal nanoparticle density per unit light transmitted area.

Problems solved by technology

However, such conventional technologies have limitations in improving production yield upon applying continuous processes or various substrate sizes.
Furthermore, the conventional technologies often lead to defective products due to defects or contaminations, in the case of requiring a mechanical contact.
In this case, however, substrate materials for nano-island formation are limited to heat-resisting materials such as glass and there is a problem of not obtaining a nanoparticle array with a high nanoparticle density.

Method used

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  • Method for manufacturing nanoparticle array, surface plasmon resonance-based sensor and method for analyzing using same
  • Method for manufacturing nanoparticle array, surface plasmon resonance-based sensor and method for analyzing using same
  • Method for manufacturing nanoparticle array, surface plasmon resonance-based sensor and method for analyzing using same

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first embodiment

[0009]In the first embodiment to solve the stated technical problem, a method for manufacturing a nanoparticle array comprises a process providing a mixed solution of an ionic binder and conductive nanoparticles; a process dipping a substrate into the mixed solution; a process applying an electric field to the substrate-dipped mixed solution for inducing coating of conductive nanoparticles onto the substrate.

second embodiment

[0010]In the second embodiment to solve the stated different technical problem, a spectroscopic analysis sensor comprises a substrate; a polymer binder layer coated on the substrate; conductive nanoparticles dispersed and immobilized on the polymer binder layer. The sensor can be a SPR-based spectroscopic analysis sensor.

third embodiment

[0011]In the third embodiment to solve the stated another different technical problem, a spectroscopic analysis method comprises a process dipping a spectroscopic analysis sensor into a target analyte-dispersed solution; a process detecting change of reflected or transmitted light on a surface of the sensor using SPR or LSPR. In another different embodiment, the above stated spectroscopic analysis method includes a process dipping two or more sensors spacially isolated and stacked into a target analyte-dispersed solution; a process detecting change in SPR- or LSPR mode-coupled reflected or transmitted light upon applying an incident light onto the sensor.

Effect of the Invention

[0012]Referring to the present invention, a cost-effective wet method to manufacture a nanoparticle array can be offered through quick and high density coating of metal nanoparticles onto the substrate by dipping the substrate into a mixed solution of an ionic binder and conductive nanoparticles followed by ap...

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Abstract

The present invention relates to a method for manufacturing a nanoparticle array, a surface plasmon resonance-based sensor, and a method for analyzing using the same. According to one embodiment of the present invention, after a mixed solution of an ionized binder and conductive nanoparticles is prepared, a substrate is dipped into the mixed solution. Thereafter, by applying an electric field to the mixed solution into which the substrate is dipped so as to induce coating of the conductive nanoparticles on the substrate, it is possible to manufacture, by a wet method, a nanoparticle array in which the conductive nanoparticles are quickly coated on the substrate with high density.

Description

INCORPORATION BY REFERENCE OF ANY PRIORITY APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 14 / 784,569, filed on Feb. 4, 2016, which is a national stage application under 35 U.S.C. § 371 of PCT Application No. PCT / KR2013 / 008182, filed on Sep. 10, 2013, which claims priority to Korean Patent Application No. 10-2013-0041228, filed on Apr. 15, 2013, and to Korean Patent Application No. 10-2013-0083142, filed on Jul. 15, 2013. Each of the above applications is incorporated herein by reference in its entirety.TECHNOLOGICAL FIELD[0002]The present invention describes a sensor technology for detecting biological or non-biological substances. In more detail, a method for manufacturing a nanoparticle array, a surface plasmon resonance-based sensor and a method for analyzing using the same.BACKGROUND TECHNOLOGY[0003]A surface plasmon resonance (SPR) refers to a phenomenon of the propagation of surface plasmon polaritons (SPPs) which are formed on or near...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G01N21/552B81C1/00
CPCG01N21/554B81C1/0038G01N2201/068B82B3/00G01N21/55
Inventor KIM, GIBUM
Owner PLEXENSE
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