Cannabinoid composition and method of sublingual, buccal and oral mucosa delivery

Abstract

A formulation includes a cannabinoid extract that is pharmaceutically effective by systemic delivery via a recipient's oral mucosal lining. The method of delivery avoids the digestive tract processing and liver metabolizing of the active ingredients of the formulation, whereby lower doses cause a desired therapeutic effect or other intended effect. Variations of the formulation include a cannabinoid extract and one or more of pregelatinized tapioca starch polymethylsilsesquioxane, bromelain, volume Fenugreek gum, vitamin B12, luo han guo fruit extract, mannitol, microcrystalline cellulose, sodium alginate, gellan gum, menthol Natural peppermint flavor or oil, Grapefruit flavored powder or oil, magnesium stearate and / or citric acid. The cannabinoid extract may include Tetrahydrocannabinol, tetrahydrocannabinolic acid, Cannabidiol, Cannabidiol acid, and / or other cannabinoid sourced from a cannabis sativa plant. The formulation includes at least one cannabinoid in a volume and measure that is pharmaceutically effective and / or effectual in achieving an intended systemic state or response of the recipient.

Description

FIELD OF THE INVENTION[0001]This disclosure relates generally to compositions that include at least one cannabinoid, and particularly to formulated cannabinoid mixtures that enable sublingual delivery of a volume of at least one cannabinoid.BACKGROUND OF THE INVENTION[0002]The terms sublingual and buccal are defined herein to refer to avenues of medication administration achieved via the mouth of a human or other mammal. Sublingual drug delivery involves placing the instant drug under a recipient's tongue to dissolve and be absorbed in the recipient's tissue. Buccal drug delivery requires placing a drug between an oral gum and cheek of a recipient, whereby the instant drug dissolves and is absorbed into the circulatory system of the recipient.[0003]The cheek and locations under the tongue of many mammals typically present numerous, pharmaceutically accessible capillaries of a potential recipient's circulatory system. Medications and other biologically active materials can thus by-pa...

AI Technical Summary

Benefits of technology

The present invention is a formulation that can be applied through the mouth and absorbed through the oral mucosal lining. It contains a cannabinoid extract and other ingredients that can be pharmaceutically effective. The formulation can be in the form of a gel, powder, or liquid. It may also include additional ingredients such as vitamins, minerals, and herbal extracts. The formulation can be used to treat various conditions such as pain, inflammation, and autoimmune diseases. The method of use involves placing the formulation in the mouth and applying it to the oral mucosal lining.

Problems solved by technology

More particularly, avoiding the metabolizing imposed by the liver can lower the required effective dose for some potential drug recipients.

The prior art fails to optimally address the full range of modalities of sublingual delivery of cannabinoids for either medical treatment or recreational use.

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