39results about How to "Achieve curative effect" patented technology

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases. The traditional Chinese medicine composition is mainly prepared from 81 kinds of traditional Chinese medicine such as radix panacis quinquefolii, placenta hominis, radix salvia miltiorrhizae, herba rhodiolae, fructus schisandrae, head of Chinese angelica, rhizoma chuanxiong, radix polygalae, hirudo, radix notoginseng, fried semen ziziphi spinosae, herba cistanches and radix rehmanniae through mutual matching. The traditional Chinese medicine composition is capable of improving general blood circulation, blood weight and blood vessel elasticity within a shorter time, and meanwhile, damp cold in a body and outer walls of blood vessels can be eliminated and removed out of the body in time; the traditional Chinese medicine composition has the function of repairing internal organs such as the liver, the kidney, the lung and the spleen and is capable of increasing the immunity and the disease resistance of the body in time; the traditional Chinese medicine composition has an obvious treatment or auxiliary treatment rehabilitation function on heart disease, cerebral thrombosis, serious insomnia, astriction, hypertension, hyperglycemia, hyperlipidemia, insufficiency of cerebral blood supply, tinnitus, cervical spondylosis and lumbar spondylosis.

The invention relates to a Prussian blue-based intelligent pH-triggered MRI drug release-monitoring synergetic nanometer diagnosis and treatment agent and a preparation method thereof. The nanometer diagnosis and treatment agent comprises hollow Prussian blue nanometer particles with mesopores. The surfaces of the hollow Prussian blue nanometer particles with mesopores are coated with KxMny[Fe(CN)6]z, wherein x is greater than or equal to 0.05 and less than or equal to 0.3, y is greater than or equal to 0.5 and less than or equal to 0.98 and z is equal to 1. The nanometer diagnosis and treatment agent comprises hollow mesoporous nanometer particles with core-shell structures. The HMPB-Mn nanometer diagnosis and treatment agent is used for tumor part pH-sensitive MRI and pH-sensitive drug release control in chemotherapy. Through combination with thermotherapy, MRI-guided thermotherapy-chemotherapy combined treatment on tumors is realized.

The invention discloses a traditional Chinese medicinal composition for treating rheumatic arthritis and rheumatoid arthritis. The composition comprises the components of: 20-50 parts by weigh of Codonopsis pilosula, 40-80 parts by weight of radix aconiti preparata, 40-80 parts by weight of prepared kusnezoff monkshood root, 20-50 parts by weight of Polygonum multiflorum, 20-50 parts by weight of papaya, 10-30 parts by weight of Achyranthes, 10-30 parts by weight of Clematis, 5-15 parts by weight of monkshood, 10-30 parts by weight of cassia twig, 10-30 parts by weight of ephedra, 20-50 parts by weight of Schizonepeta, 10-30 parts by weight of the root of fangfeng, 10-30 parts by weight of notopterygium, 10-30 parts by weight of Gastrodia elata, 10-30 parts by weight of safflower, 10-30 parts by weight of eucommia, 10-30 parts by weight of Acanthopanax bark, 5-15 parts by weight of Asarum, 10-30 parts by weight of rhizoma atractylodis, 20-50 parts by weight of angelica, 10-30 parts by weight of Ligusticum wallichii, 10-30 parts by weight of Radix Aucklandiae, 20-50 parts by weight of Rhizoma Alpiniae Officinarum, 20-50 parts by weight of clove and 10-30 parts by weight of dried orange peel. The invention also discloses a preparation method of the above traditional Chinese medicinal composition. The traditional Chinese medicinal composition has curative effect.

The invention discloses a traditional Chinese medicinal composition for treating insomnia. The traditional Chinese medicinal composition for treating insomnia comprises the following components by weight: 45-55 parts of Radix Paeoniae Alba, 45-55 parts of semen zizyphi spinosae, 45-55 parts of lily, 45-55 parts of rose, 55-65 parts of tuber fleeceflower stem, 25-35 parts of evodia rutaecarpa, 5-15 parts of dried ginger, 5-15 parts of borneol and 5-15 parts of cinnamon. The invention also discloses a preparation method of the above traditional Chinese medicinal composition for treating insomnia. The traditional Chinese medicinal composition for the treating insomnia has the advantages of low cost, exact curative effect and fast effectiveness, and can achieve radical curative effect.

The invention relates to image analysis software for radionuclide pulmonary perfusion and ventilation tomography. The newly-developed computer software is utilized to implement three-dimensional registration for a pulmonary perfusion imaging tomography image and a pulmonary ventilation imaging tomography image, so that the pulmonary perfusion imaging tomography image and the pulmonary ventilation imaging tomography image reach good correspondence in a spatial position. Accordingly, a non-matching area and a matching area of the pulmonary perfusion imaging tomography image and the pulmonary ventilation imaging tomography image can be indentified and confirmed in range and degree. Therefore, a pulmonary embolism diseased region can be automatically identified, and the range and the volume of diseased lung tissue can be automatically identified. The quantitative analysis software for the pulmonary perfusion and ventilation tomography can be used for qualitative and quantitative diagnosis for pulmonary embolism and quantitative therapeutic effect evaluation for the pulmonary embolism.

The invention relates to an oral liquid of leukotriene antagonist against allergy, inflammation, asthma that can be used as cell protecting agent, comprising at least a buffer solution and Montelukast dissolved in the buffer solution and its pharmaceutically acceptable salts. The pH of the buffer solution is between 7-11, and the buffer solution includes at least water, pharmaceutically acceptable alcohols, buffering agents and pharmaceutically acceptable additives.

The invention discloses a preparation method and application of engineered drug-loaded cell membrane vesicles loaded with small-molecule chemotherapeutic drugs and over-expressed in TIGIT. The preparation method comprises the following steps: S1, packaging viruses, and preparing and collecting a specific lentivirus solution for coding a TIGIT gene; s2, infecting target cells by using the obtained lentivirus solution, and screening by using a resistant drug so as to construct a stable cell line of an overexpressed TIGIT gene; s3, culturing the obtained stable cell line, extracting cell membranes of the stable cell line, preparing the cell membranes into membrane nano-vesicles, and centrifugally purifying the membrane nano-vesicles to obtain engineered cell membrane vesicles; and S4, loading a small molecule chemotherapeutic drug by using the obtained cell membrane vesicle, and carrying out centrifugal purification to obtain the engineered drug-loaded cell membrane vesicle. The engineered drug-loaded cell membrane vesicle prepared by the invention is good in biological safety, shows an excellent effect in immunotherapy of tumors, and has relatively good clinical transformation value and application prospect.

The invention discloses a phase-change nanobubble, and a preparation method and application thereof. The nanobubble is prepared by taking an amphiphilic material chitosan-polylactic acid grafted copolymer as a coating material and taking perfluoropentane capable of generating liquid-gas phase transformation under the action of temperature as a bubble core filling substance by adopting an emulsifying solvent volatilization method. The prepared nanobubble is creamy yellow, and the particle size is 101.1+/-2.7 nm. The particle size change is small in two months in vitro, and stability is good. The nanobubble can enhance the ultrasonic imaging effect under action of ultrasonic waves and can be broken by the ultrasonic waves. The chitosan-polylactic acid grafted copolymer nanobubble prepared bythe emulsifying solvent evaporation method is good in in-vitro stability, and ultrasonic imaging can be enhanced. The nanobubble can load an MRI contrast agent, so that the MRI imaging effect of tumor lesions is improved. The nanobubble can also load anti-tumor drugs for targeted therapy of tumors, is a novel multifunctional iconography nano contrast agent integrating diagnosis and treatment, andthus has a great application value.

Belonging to the technical field of biomedicine, the invention specifically relates to an in-vivo phase transition tumor targeted nanobubble, its preparation method and application. The nanobubble takes a polyphosphate-polyester copolymer of a coupling tumor targeting factor as a coating material, adopts perfluoropentane able to undergo liquid-gas phase transition in vivo as a bubble core filling material, and is prepared by a pre-multiple emulsion-hollow membrane tube emulsification method. When the nanobubble enters the body, the liquid perfluoropentane undergoes liquid-gas phase transition at body temperature to form a gas-containing nanobubble. By means of the specific combination of a targeting factor and a tumor cell, the nanobubble can concentrate a tumor focus part, thus improving the tumor focus ultrasonic imaging effect. The nanobubble can be loaded with an MRI contrast agent to improve the tumor focus MRI imaging effect. The nanobubble can also be loaded with an antitumor drug and used for targeted treatment of tumors, thus being a novel diagnosis-treatment integrated multifunctional imageological nano-contrast agent.

The invention discloses an intelligent moxibustion physiotherapy instrument. The intelligent moxibustion physiotherapy instrument comprises an execution unit and a power supply control unit; the execution unit comprises a shell fixing part, a motion mechanism, a heating moxibustion terminal, an essential oil part, a temperature sensing part and a magnet therapy part; the power supply control unitis connected with the execution unit through a high temperature resistant cable; the power supply control unit comprises a remote controller panel, a controller, a display screen and a buzzer; a functional area on the remote controller panel has moxibustion modes, temperature levels, moxibustion time and reinforcing and reducing manipulations; and the controller is connected with a motor, a heating terminal I, a heating terminal II and a temperature sensor through wires, and a manual temperature adjusting knob is additionally arranged on the power supply control unit. According to the intelligent moxibustion physiotherapy instrument, traditional Chinese medicine and modern electromechanical theories are perfectly combined, the limitation of traditional moxibustion operation and the defectsof an existing moxibustion instrument are overcome, operation is easy, special care is not needed, the treatment effect is remarkable, safety and reliability are achieved, popularization is convenient, and the moxibustion therapy which is the Chinese National Treasury can be effectively promoted.

The invention discloses a cupping glass. The cupping glass comprises a cupping jar body, an outer wall and a cupping jar cover. A cupping jar edge is formed at the bottom of the cupping jar body, the width of the cupping jar edge is larger than that of the cupping jar body, and the corners of the cupping jar edge are in smooth transition. Multiple vent holes are formed in the upper portion of the cupping jar body, and an inner cavity is formed in the cupping jar body. The outer wall is arranged on the periphery of the cupping jar body and covers the vent holes, the bottom of the outer wall is connected with the cupping jar body in a sealed mode, and an upper opening is formed in the top of the outer wall. An outer cavity is formed between the outer wall and the cupping jar body, the cupping jar body covers the upper opening, and a switching vent valve and a safety valve are arranged on the cupping jar cover. The cupping glass has the advantages that operation is convenient, safety is high, no harm is caused to skin of a treated person, and the treatment effect can be rapidly achieved.

The invention discloses a preparation method of a mesoporous silica complex with drug controlled release and imaging functions. The preparation method comprises the following steps of (1) preparing anAu/Fe3O4@mSiO2-SH molecular probe; firstly, preparing Au nanoparticles; secondly, preparing Au/Fe3O4 nano particles with a shell-core structure; then, preparing Au/Fe3O4@mSiO2-SH nanoparticles by applying a reversed-phase microemulsion method; (2) preparing Au/Fe3O4@mSiO2/DOX-SS-PEG-HA; adding Au/Fe3O4@mSiO2-SH nanoparticles into a DOX ethanol solution, performing dispersing of the obtained nanoparticles into a DMSO aqueous solution, and adding SH-PEG-NH2, so as to obtain nanoparticles Au/Fe3O4@mSiO2/DOX-SS-PEG-NH2; enabling HA to be dissolved in an MES solution through a carbodiimide method,enabling EDC and NHS to be added to serve as coupling agents, and enabling Au/Fe3O4@mSiO2/DOX-SS-PEG-NH2 to be added. The nanoprobe has three imaging functions of MRI, MPI and PAI and chemotherapy and photo-thermal treatment functions, can realize comprehensive, sensitive and targeted imaging of tumors, can perform real-time quantitative in-vivo monitoring of drug curative effects, and opens up abrand new field for accurate diagnosis and treatment of tumors at the molecular level.

The invention relates to the field of antitumor food, in particular to application and a preparation method of roe polypeptide. The application refers to application of the roe polypeptide in preparation of antitumor and tumor prevention and treatment food. The preparation method of the roe polypeptide comprises the steps as follows: 1) collection of roe cells; 2) thorough cleaning, cell homogenization, freezing and thawing, sedimentation, taking of supernatant, interception and impurity removal and detection treatment of the roe cells; 3) preparation of a roe polypeptide stock solution; and 4) preparation of roe polypeptide powder, mother liquor or solution. Roes play antitumor and anticancer functions by the inhibition effect on melanoma and tumor. Fish byproducts are efficiently utilized in medicines and food and create social benefits for economic development. Compared with a traditional antitumor drug preparation, as bioactive peptides naturally exist in the roe polypeptide stocksolution obtained by roe extraction, the components of the roe polypeptide have certain safety, as an antitumor drug or health food, the roe polypeptide has safety and reliability higher than that oftraditional antitumor drug preparation.

The invention discloses a traditional Chinese medicine snack pastry for children to eat and a preparation technology thereof, belongs to the technical field of food processing technologies, and mainly solves the technical problems that existing snacks for children are high in additive content and not beneficial to healthy growth of children. According to the technical scheme, the traditional Chinese medicine snack pastry for children to eat is prepared from, by weight, 2 parts of codonopsis pilosula, 2 parts of platycodon grandiflorum, 15 parts of poria cocos, 10 parts of coix seeds, 500 parts of Chinese yam, 10 parts of white hyacinth beans, 50 parts of lotus seeds, 500 parts of hawthorn fruits, 250 parts of sugar, 3-5 parts of lemon juice, 10 parts of pericarpium citri reticulatae, 250 parts of flour and 250 parts of glutinous rice flour. The preparation technology of the traditional Chinese medicine snack pastry for children to eat according to the claim 1 comprises the following steps: pretreating hawthorn fruits; boiling hawthorn fruit jelly stuffing; decocting to obtain liquid medicine; preparing pastry outer blanks; wrapping the pastries; and sterilizing and packaging. The product has the advantages of being natural, healthy, good in taste, health-care, simple in preparation process and the like.