The invention discloses a fresh-extracted and freeze-dried white peony root granule decoction piece. The fresh-extracted and freeze-dried white peony root granule decoction piece is mainly characterized in that the fresh-extracted and freeze-dried white peony root granule decoction piece is prepared through the following steps: harvesting of white peony roots, washing while fresh, slicing, juicing, extraction, extract concentrating for forming a clear paste, freeze drying, crushing, granulation, drying, granule finishing, and packaging. The decoction piece has a stable quality, can be decoctedto form a decoction, also can be directly processed to form a pill, a powder, a tablet or a capsule, is portable, and can be conveniently used clinically.