Production process for increasing TCM particle moisture-proof property
A technology of traditional Chinese medicine granules and moisture-proof performance, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and bulk transportation, etc., can solve the problems of poor stability of finished products, loss of active ingredients, and high labor intensity, and is conducive to environmental protection, The effect of preventing moisture absorption problems and improving product quality
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Embodiment 1
[0019] (Example 1, Yiganning granule preparation process)
[0020] Prescription: The medical materials in this embodiment have 13 crude drugs, their names and dosages are: 606g of Radix Astragali, 408g of Hedyotis diffusa, 606g of Capillary, 408g of Desmodium, 490g of Codonopsis, 408g of Dandelion, 490g of Radix Polygoni Multiflori, 408g of Cortex Moutan, Danshen 490g, Poria 408g, Baishao 408g, Atractylodes macrocephala 408g, Toosendan 408g.
[0021] Preparation method: In the above thirteen herbs, decoct Astragalus with water twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.30 (relative to water, measured at 20°C Obtain) and become clear ointment stand-by; Extract volatile oil from capillary wormwood, use β-cyclodextrin (or claim beta cyclodextrin, English name: Betacvclodextrin) 290g clathrate, obtain capillary wormwood volatile oil clathrate for subsequent use; Follow the steps below:
[0022] (a) Ex...
Embodiment 2
[0027] (Example 2, preparation process of Lvjiao Buxue Granules)
[0028] Prescription: The medicinal materials in this example include 6 crude drugs, their names and dosages are: 216g donkey-hide gelatin, 180g astragalus, 180g codonopsis, 120g rehmannia glutinosa, 90g atractylodes macrocephala, and 60g angelica.
[0029] Preparation method: For the above six flavors, distill Angelica and Atractylodes Rhizoma Atractylodes Rhizome, collect the distillate for later use; then proceed as follows:
[0030] (a) Extraction of the remaining crude drugs: decoct the residues of Angelica Sinensis and Atractylodes Rhizoma Atractylodes Rhizome with astragalus, Codonopsis pilosula, and Rehmannia glutinosa with water three times, for 2.0 hours for the first time, and 1.0 hours for the second and third times, combine the decoctions, and filter to obtain the extract .
[0031] (b) Flocculate and clarify the extract, and then filter to obtain the filtrate: heat the extract to 70° C., and conce...
Embodiment 3
[0035] (Example 3, Yiganning granule preparation process)
[0036] Prescription: The medical materials in this embodiment have 13 crude drugs, their names and dosages are: 606g of Radix Astragali, 408g of Hedyotis diffusa, 606g of Capillary, 408g of Desmodium, 490g of Codonopsis, 408g of Dandelion, 490g of Radix Polygoni Multiflori, 408g of Cortex Moutan, Danshen 490g, Poria 408g, Baishao 408g, Atractylodes macrocephala 408g, Toosendan 408g.
[0037] Preparation method: the rest are the same as in Example 1, except that in step (b), the extract is heated to 90° C. and then concentrated until the ratio of the number of milliliters to the number of grams of the whole crude drug is 8:1. Adjust the pH to 4, add chitosan colloid solution with a weight percentage concentration of 1% while it is hot at 90°C, and add 1.0ml of crude drug per gram of crude drug based on the weight percentage concentration of 1% chitosan For the sugar colloid solution, the time to continue stirring was ...
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