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Effective parts of Japanese creeper and use of effective ingredient of Japanese creeper in preparation of medicine against fungus

A technology of Dijincao and fungi, which is applied in the direction of medical preparations containing active ingredients, antifungal agents, plant/algae/fungus/moss components, etc., can solve problems such as failure to achieve the expected purpose, and achieve significant curative effect

Inactive Publication Date: 2009-09-16
斯拉甫·艾白
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, there is still traditional Chinese medicine treatment, but it has not achieved the expected purpose

Method used

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  • Effective parts of Japanese creeper and use of effective ingredient of Japanese creeper in preparation of medicine against fungus
  • Effective parts of Japanese creeper and use of effective ingredient of Japanese creeper in preparation of medicine against fungus
  • Effective parts of Japanese creeper and use of effective ingredient of Japanese creeper in preparation of medicine against fungus

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Embodiment

[0011] The effective parts of Dijincao and its active ingredients are used as the preparation of antifungal drugs, and the effective parts of Dijincao are obtained by conventional water extraction method or alcohol extraction method or macroporous resin extraction or organic solvent extraction method, including flavonoids , tannins, organic acids, sterols, terpenes and tannins, coumarins, phenolic acids and fat-soluble components, etc., and active ingredients include ellagic acid, brevifolia hematoxylin, apigenin-7-O-glucoside, osmanthus Herbacetin-7-O-glucoside, quercetin-3-O-arabinoside, β-sitosterol, gallic acid, quercetin, kaempferol, quercetin-3-O-(2″, 3″ -di-O-galloyl)-β-D-glucopyranoside, eumaculin E (eumaculinE), eumaculinB, eumaculinD, etc.

[0012] The extracted effective parts of Dijincao and the active ingredients of Dijincao are mixed according to conventional methods or prepared into oral and external preparations respectively.

[0013] Antifungal test of Dijinc...

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Abstract

The present invention relates to the use of the effective parts of Dijincao and its active ingredients as medicines with antifungal effects. The effective parts of Dijincao and the effective parts of Dijincao are obtained by conventional water extraction, alcohol extraction, macroporous resin extraction or organic solvent extraction. Active ingredients. The clinical observation results of 41 patients with superficial mycosis treated with Dijincao extract (effective part and its active ingredients) showed that the preparation significantly improved the clinical symptoms and signs of patients with superficial mycosis, and the total clinical effective rate was 97.92% %, the recovery rate is 85.92%, the effective rate is 12.0%, and the invalid rate is 2.25%. It has no obvious toxic and side effects, and is a good medicine for treating superficial mycosis.

Description

technical field [0001] The invention relates to the medicinal application of the effective parts of Dijincao and its active ingredients, especially the application of antifungal drugs. Background technique [0002] Euphorbia humifusa Willd. or Euphorbia maculata L. is the dried whole herb of Euphorbiaceae. It has the functions of clearing away heat and detoxification, cooling blood and stopping bleeding. Currently, it is mostly used clinically to treat bacillary dysentery, enteritis, viral hepatitis, hemoptysis, hematuria, and hematochezia. However, there is no report about the effective parts and active ingredients of Dijincao as medicines with antifungal effects. [0003] In recent years, the incidence of superficial mycoses has continued to increase, especially in marginal areas. There are many types of pathogenic bacteria, mainly Trichophyton rubrum and Trichophyton gypsum. Although there are many new antifungal drugs (administered internally and externally), due to th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/47A61P31/10
Inventor 斯拉甫·艾白古力娜·达吾提努尔买买提·艾买提艾则孜·亚森
Owner 斯拉甫·艾白