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A Chinese medicinal composition for treating thrombus
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A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, drug delivery, blood diseases, etc., can solve the problems of slow onset of warfarin sodium, long half-life of pentosan sodium, massive bleeding, etc.
Inactive Publication Date: 2010-03-03
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology
However, western medicine has a lot of side effects, and improper medication can cause serious consequences, such as aspirin can cause massive bleeding; warfarinsodium has a slow onset of action and is difficult to respond to emergencies; the effect is too long and difficult to control; pentosan sodium has a long half-life
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Embodiment 1
[0017] The preparation of embodiment 1 " Luotong " granule or capsule
[0018] The three medicinal materials are weighed according to the ratio of 4 parts by weight of Astragalus membranaceus, 3 parts by weight of Radix Paeoniae Rubra, and 3 parts by weight of Pueraria Radix Puerariae, mixed, and decocted twice, adding 10 times the amount of water for the first time, decocting for 2 hours, and adding water for the second time 8 times the amount, decoct for 1 hour, combine the secondary filtrates, concentrate under reduced pressure until each 1ml contains 1g of crude drug, add an equivalent amount of 95% ethanol, stir well, let stand for 12 hours, filter, after recovering ethanol from the filtrate, add AB- 8 Macroporous adsorption resin, first eluted with water until colorless, then eluted with 70% ethanol, collected the 70% ethanol eluate, recovered ethanol, concentrated to a thick paste, and vacuum dried to obtain the intermediate of Luotonggan extract. Add metered pharmaceut...
Embodiment 2
[0019] The preparation of embodiment 2 " Luotong powder injection "
[0020] Dissolve the dry extract of Luotong extract in water for injection, add metered pharmaceutical excipients, adjust the pH to 6.0, filter through a microporous membrane, and vacuum-dry to obtain sterile powder, which is divided into vials to prepare Each bottle contains two specifications of sterile powder 100mg and 200mg, crimped and sealed, and packed after passing the inspection.
Embodiment 3
[0021] Example 3 Preparation of "Luotong Freeze-dried Powder Injection"
[0022] Take the dry extract of Luotong extract, dissolve it with water for injection, add metered water-soluble pharmaceutical excipients for injection, adjust the pH to 6.0, ultra-filter, put in vials, 5mL each, freeze-dry, seal , package after passing the inspection, and get ready.
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Abstract
The invention relates to a Chinese medicinal composition for treating thrombus, which is prepared from astragalus root, radix paeoniae rubrathe and kudzuvine root by weight ratio of 2-6, 1-5, 1-5, preferably 3-5, 2-4, 2-4. By charging right amount of pharmaceutically acceptable auxiliary materials, the composition can be prepared into tablets, capsules, granules, oral liquids or injections.
Description
[0001] Field [0002] The invention relates to a traditional Chinese medicine composition capable of resisting thrombus, improving cardiovascular and cerebrovascular insufficiency, and treating cardiovascular and cerebrovascular diseases, belonging to the field of traditional Chinese medicine preparation. Background technique [0003] Cardiovascular and cerebrovascular diseases, especially thrombosis and cardiovascular and cerebrovascular insufficiency, have become one of the major diseases that seriously threaten the health and life of middle-aged and elderly people. Modern drugs for treating cardiovascular and cerebrovascular diseases are mainly western medicines, such as antithromboticaspirin, Warfarinsodium, pentosan sodium; tolperidone hydrochloride to improve cardiovascular and cerebrovascular insufficiency, etc. However, Western medicine has a lot of side effects, and improper medication can have serious consequences, such as aspirin can cause massive hemorrhage; warf...
Claims
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Application Information
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