Nerve growth factor production inhibitor and external preparation for skin, cosmetic, quasi medicine, itch prophylactic and therapeutic agent and atopic dermatitis therapeutic agent mixed with the ner

A technology of nerve growth factor and skin external preparation, which is applied in the field of nerve growth factor production inhibitors, can solve the problem that itching inhibitors have not yet been developed, and achieve high safety effects

Inactive Publication Date: 2007-09-12
PIAS ARISE KK +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In summary, the current status quo has not yet developed an itch inhibitor whose mechanism of action is to inhibit the elongation of C fibers to the epidermis of the skin

Method used

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  • Nerve growth factor production inhibitor and external preparation for skin, cosmetic, quasi medicine, itch prophylactic and therapeutic agent and atopic dermatitis therapeutic agent mixed with the ner
  • Nerve growth factor production inhibitor and external preparation for skin, cosmetic, quasi medicine, itch prophylactic and therapeutic agent and atopic dermatitis therapeutic agent mixed with the ner
  • Nerve growth factor production inhibitor and external preparation for skin, cosmetic, quasi medicine, itch prophylactic and therapeutic agent and atopic dermatitis therapeutic agent mixed with the ner

Examples

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Embodiment 1

[0029] This example is an example of a nerve growth factor production inhibitor containing acerolae seed extract. 140 kg of an aqueous 1,3-butanediol solution having a 1,3-butanediol content of 30% by weight was added to 80 kg of pulverized acerolae seeds, and stirred overnight at room temperature. After all centrifugation treatments, the supernatant was filtered with a 0.22 μm filter to obtain acerola seed extract. The dry solid content was 0.71% by weight.

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PUM

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Abstract

It is intended to provide a nerve growth factor production inhibitor which has an effect of inhibiting the production of the nerve growth factor deeply participating in the extension of C fiber toward the epidermis and a high safety; and an external preparation for the skin, a cosmetic, a quasi drug, a preventive and remedy for itching and a remedy for atopic dermatitis containing this nerve growth factor production inhibitor. A nerve growth factor production inhibitor characterized by containing an acerola seed extract.

Description

technical field [0001] The present invention relates to an inhibitor of nerve growth factor production, and external skin preparations, cosmetics, quasi-drugs, agents for preventing and treating itching, and agents for treating atopic dermatitis containing the inhibitor of nerve growth factor production. Background technique [0002] Pruritus is a characteristic sensation produced only on the skin, mucous membrane, cornea, etc., and is described as "an uncomfortable feeling accompanied by a desire to scratch". In inflammatory and allergic skin diseases such as atopic dermatitis, hay fever, food allergies, and urticaria, which are becoming social problems in recent years, this feeling called itching is one of the most important and serious symptoms. . In addition, senile pruritus and jaundice accompanied by dry skin, itching accompanied by dialysis, and itching in complications of diabetes and malignant tumors are also becoming problems. [0003] Pruritus is induced as peri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/18A61K8/00A61Q19/00A61P17/04A61P17/16A61P37/08A61P43/00
CPCA61K36/736A61P17/00A61P17/04A61P17/16A61P37/08A61P43/00
Inventor 殿垣内浩仲尾次浩一酒井薰滨田和彦永峰贤一
Owner PIAS ARISE KK
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