O/W emulsion composition
An emulsion composition and the technology of the composition are applied in the directions of drug combination, emulsion delivery, medical preparations of inactive ingredients, etc., can solve the problems of not being able to obtain an emulsion composition, etc., and achieve high safety, little irritation, and extension. light effect
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Embodiment 1
[0055] Medium Chain Fatty Acid Triglycerides 13w / w%
[0056] Carboxyvinyl polymer 0.5w / w%
[0057] Partially saponified polyvinyl alcohol (saponification degree 86.5~89.0mol%) 1w / w%
[0058] 1,3-Butanediol 10w / w%
[0059] Appropriate amount of diisopropanolamine
[0060] Refined water make up to 100w / w%
[0061] pH5.1
[0062] 0.5 g of carboxyvinyl polymer was dispersed in 25 g of purified water, and heated to about 70° C. to obtain an aqueous solution. Further, 1 g of partially saponified polyvinyl alcohol was dissolved in 25 g of purified water heated to about 70° C. to obtain an aqueous solution. The 2 aqueous solutions were combined as the aqueous phase. Separately, a mixture of 13 g of medium-chain fatty acid triglyceride and 10 g of 1,3-butanediol was heated to about 70° C., and diisopropanolamine (appropriate amount) was dissolved therein to form an oil phase. Add the oil phase to the water phase, then add the remaining purified water, stir until uniform, and coo...
Embodiment 2
[0064] Cetyl Alcohol 4w / w%
[0065] Isopropyl myristate 12w / w%
[0066] Carboxyvinyl polymer 0.8w / w%
[0067] Partially saponified polyvinyl alcohol (saponification degree 86.5~89.0mol%) 1.2w / w%
[0068] Glycerin 5w / w%
[0069] Appropriate amount of sodium hydroxide
[0070] Refined water make up to 100w / w%
[0071] pH4.8
[0072] 0.8 g of carboxyvinyl polymer was dispersed in 40 g of purified water, and heated to about 70° C. to obtain an aqueous solution. Further, 1.2 g of partially saponified polyvinyl alcohol was dissolved in 20 g of purified water heated to about 70° C. to obtain an aqueous solution. The 2 aqueous solutions were combined as the aqueous phase. Separately, 12 g of isopropyl myristate, 4 g of cetyl alcohol, and 5 g of glycerin were heated to about 70° C. to form an oil phase. Add the oil phase to the water phase, stir evenly, add a solution obtained by dissolving sodium hydroxide (appropriate amount) in the remaining purified water, and then cool to ...
Embodiment 3
[0074] Isopropyl myristate 10w / w%
[0075] Stearyl Alcohol 2w / w%
[0076] Carboxyvinyl polymer 0.5w / w%
[0077] Partially saponified polyvinyl alcohol (saponification degree 86.5~89.0mol%) 0.8w / w%
[0078] Appropriate amount of triethanolamine
[0079] Refined water make up to 100w / w%
[0080] pH6.0
[0081] 0.5 g of carboxyvinyl polymer was dispersed in 25 g of purified water, and heated to about 70° C. to obtain an aqueous solution. Further, 0.8 g of partially saponified polyvinyl alcohol was dissolved in 25 g of purified water heated to about 70° C. to obtain an aqueous solution. The 2 aqueous solutions were combined as the aqueous phase. Separately, a mixture of 10 g of isopropyl myristate and 2 g of stearyl alcohol was heated to about 70° C. to form an oil phase. The oil phase was added to the water phase, and after stirring, a solution obtained by dissolving triethanolamine (appropriate amount) in the remaining purified water was added, and the mixture was cooled ...
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