Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine

A technology of cell subsets and stem cells, applied in the field of optical sensors, can solve the problem of lack of cell processing ability

Active Publication Date: 2008-03-19
BIOSAFE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Examples include the fields of cardiology, orthopedics and neurology, all of which are experimenting with stem cell-based treatments, but lack adequate cell processing capabilities

Method used

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  • Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine
  • Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine
  • Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine

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Embodiment Construction

[0022] The present invention relates to an integrated system of collection of cell subpopulations, treatment / concentration of cell subpopulations and reinfusion of enriched products of specific cell subpopulations for repair or regeneration of injured or defective tissue.

[0023] This method will be illustrated in an autologous treatment setting, which means that cells are withdrawn from the same patient and reinfused into the same patient. Such autologous treatment is generally preferred in the absence of an immune response due to incompatibility between donor and recipient. But for heterogeneous processing devices, the principle remains the same.

[0024] According to current knowledge, stem cells, more specifically mesenchymal stem cells, are found in the bone marrow, although studies have shown that mesenchymal stem cells are also present in umbilical cord blood, peripheral blood or even adipose tissue. Although the principles can also be applied to various stem cell sou...

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PUM

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Abstract

A system for the extraction, collection, processing and transplantation of cell subsets, including adult stem cells and platelets, in particular for tissue repair in regenerative medicine, comprises a set of disposable fluid- transport elements that are pre-connected or that include aseptic connectors for making interconnections between them in an aseptic manner or are adapted to be aseptically connected. The set usually includes three kits of disposable sterile elements, a collection kit, a processing kit, and a transplantation kit packaged in a blister pack on a support such as a tray, having one compartment for receiving each inter-connectable kit of the set. The set includes an extracting device, for example including a needle for bone puncture or vein puncture, for extracting bone marrow or other sources of cell subsets from a patient.

Description

technical field [0001] The present invention involves the collection, automated processing and transplantation of subpopulations of cells as found in bone marrow, peripheral blood, umbilical cord blood or adipose tissue for local reinfusion of these cells to repair tissue. The subpopulation of cells is typically adult stem cells or platelets, but more generally includes any subpopulation of cellular red and white blood cells. These procedures are readily performed in a hospital setting or medical facility without a cell processing laboratory, and are easily performed by technicians without specialized skills. The present invention also includes novel optical sensors for monitoring cell subpopulations passing through the transparent tube. Background technique [0002] Stem cells are defined as cells capable of asexual reproduction and self-renewal, and capable of differentiating into multiple cell lines. Whereas embryonic stem cells are derived from mammalian embryos at the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02A61M1/36
CPCA61M1/3693A61M2001/3698A61M1/0209A61M1/3698A61M2202/0437A61M2202/0462A61M2202/08A61M2202/10A61M1/0218A61P17/02A61P19/04A61P19/08A61P21/00A61P25/00A61P43/00A61P9/00
Inventor C·费尔
Owner BIOSAFE SA
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