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Discrete patch for viral lesions

A trauma and virus technology applied in the field of discrete films

Inactive Publication Date: 2008-05-14
JOHNSON & JOHNSON CONSUMER COPANIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Despite the teachings of the prior art, there is a continuing need for discrete coverings for viral wounds that protect and promote wound healing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] at 30g / m 2 A coat weight of Lintec Ohkura 85NES50 clear polyurethane film (50 microns thick) was coated with LS486H solvent-based acrylic adhesive without hydrocolloid particles. A Tekkote silicone release liner was applied over the coated film. The laminate was cut into circular dressings of the invention with a diameter of 20 mm.

Embodiment 2

[0034] at 50g / m 2 coat weights of a clear perforated three-layer ABA polyethylene outer layer and amorphous polyolefin inner layer film (Cat. No. 27936, target thickness of 100 microns). A Tekkote silicone release liner was applied over the coated film. The laminate was cut into circular dressings of the invention with a diameter of 20 mm.

Embodiment 3

[0036] at 30g / m 2 The minimum coating weight, with A16 solvent-based acrylic adhesive (ID31 / EU31B National Duro Tak adhesive) substantially free of hydrocolloid particles, coated with high-impact polystyrene film (unit weight of 105g / m 2 ) Smith & Nephew opaque biaxially embossed PBA 74 polyurethane. A Tekkote silicone release liner was applied over the coated film. The laminate was cut into circular dressings of the invention with a diameter of 15mm.

[0037] This was a single center, evaluator-blinded, randomized parallel group study. Study subjects with a history of recurrent herpes cold sores (RHL) were assigned to one of three treatment groups with one of three investigated cold sore tablets. Subjects were instructed to return to the study center within 24 hours of first symptom onset for clinical evaluation. A designated researcher (who was blinded to the treatment assignments of all study subjects) performed a clinical assessment of each study visitor. Subjects com...

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PUM

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Abstract

The invention is a discrete patch suitable for use in the treatment of a viral lesion, which patch includes a backing layer and an adhesive layer, where the adhesive layer is substantially free of hydrocolloid particles, and the patch has a thickness ranging from about 10 microns to about 1,500 microns and is substantially free of topical anti-acne agents, and methods for treating viral lesions where a discrete patch of the invention is applied to a viral lesion and maintained in contact therewith for a time effective to substantially complete re-epithelialization of the lesion.

Description

technical field [0001] The present invention relates to discrete patches for viral lesions, such as cold sores, and methods for treating viral lesions. Background technique [0002] Herpes simplex virus is known to cause open wounds or sores to form in those afflicted by the disease. The herpes simplex-1 virus is known to cause cold sores to form around the mouth. Cold sores are characterized by an initial itching or burning phase, followed by visible outbreaks of viral wounds. The wound is moist and if left uncovered dries out into an itchy scab that breaks open. Outbreaks usually last 1-2 weeks. Herpes simplex-2 virus is known to cause genital sores. Other viral outbreaks, such as shingles or chickenpox, are caused by shingles. Wounds or sores (hereinafter "wounds") associated with the herpes virus dry out and open over time and can be very painful. Those afflicted by the virus are often haunted by the presence of trauma. Accordingly, there is a need for discrete co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/00
CPCA61F2013/00259A61F13/023A61F2013/00868A61F2013/00872A61F2013/00263
Inventor W·哈特
Owner JOHNSON & JOHNSON CONSUMER COPANIES
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