Novel non-woven fabric wound dressing and preparation method and application thereof

Abstract

The invention discloses a novel non-woven fabric wound dressing and a preparation method and application thereof. The wound dressing is prepared from modified polyester fibers, modified chitosan fibers and modified calcium alginate fibers through a spunlace or needling non-woven processing procedure, wherein the modified polyester fibers are 20-40 parts by mass, the modified chitosan fibers are 10-20 parts by mass, and the modified calcium alginate fibers are 10-40 parts by mass; the modified polyester fibers contain 5-10 wt% of nano silver, the modified chitosan fibers contain 0.1-1 wt% of copper ions, and the modified calcium alginate fibers contain 0.1-2 wt% of zinc ions; and the invention also discloses the application of the novel non-woven fabric wound dressing in skin wound covering dressings. According to the wound dressing, the antibacterial effect can penetrate through the whole wound healing process, the effects of promoting angiogenesis, promoting reepithelization and the like can be achieved, and therefore the effective promoting or auxiliary accelerating effect is achieved in the wound healing process.

Description

technical field [0001] The invention relates to the technical field of wound dressings, in particular to a novel non-woven wound dressing and its preparation method and application. Background technique [0002] The skin is the largest organ of the human body. People will inevitably encounter various wounds in production and life. Using dressings to cover exposed wounds is a common method of wound care in clinical practice. Currently, the most widely used dressings are Traditional cotton gauze; but with the development of science and technology and the improvement of living standards, people put forward higher requirements for medical dressings. Traditional cotton gauze has been difficult to meet the actual needs, and more and more of them are replaced by new medical dressings. , such as making conventional medical dressings contain silver ions, thereby obtaining novel medical dressings with antibacterial effects, Chinese invention CN109453409A, this patent discloses a kind ...

AI Technical Summary

Problems solved by technology

[0002]The skin is the largest organ of the human body. People will inevitably encounter various wounds in production and life, and it is commonly used clinically to cover exposed wounds with dressings A method of wound care. Traditional cotton gauze is the most widely used dressing at present; however, with the development of science and technology and the improvement of living standards, people put forward higher requirements for medical dressings, which cannot be met by traditional cotton gauze. Actual demand, it is more and more replaced by new medical dressings, such as making conventional medical dressings contain silver ions, thereby obtaining new medical dressings with antibacterial effect, Chinese invention CN109453409A, this patent discloses a kind of antibacterial medical dressings, It is prepared by the following method: mixing medical sterile dressings and dopamine hydrochloride in tris hydroxymethylaminomethane solution, adding AgNO3 aqueous solution, and preparing silver-loaded antibacterial agents under stirring conditions at room temperature and away from light. Medical dressing, although the new medical dressing of this patent can obtain better antibacterial effect, but the raw materials used are relatively expensive, and it is not easy to produce on a large scale

At the same time, an ideal wound dressing should not only play part of the function of the skin, provide a moist environment conducive to wound healing, even protect against bacterial invasion, but also accelerate or assist wound epithelialization or transition to permanent reconstruction. However, the current medical dressing has a single function, and it is difficult to effectively achieve antibacterial effects on wound angiogenesis, wound epithelialization, etc., and cannot significantly and effectively promote wound healing.

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