The invention discloses a PP-BST3-x
implant as well as a preparation method and application thereof, and belongs to the technical field of medical materials. According to the method,
oxygen vacancies (BST3-x) are constructed on the surface of
strontium ion doped
barium titanate, so that
electron movement in the material is enhanced under an ultrasonic condition,
electron holes are easier to separate, the reaction between electrons and surrounding substances is accelerated, and the ROS generation efficiency is improved. In addition, according to the PP-BST3-x
implant prepared by the invention, on one hand, macrophages can be polarized through potentials, so that
inflammation is inhibited; on the other hand, Sr release can be adjusted through
ultrasound, then
osteoclast differentiation in the infection environment is inhibited, double-path osteogenesis is achieved, the high
osteoclast environment brought by the bacterial microenvironment is improved while
bacteria are inhibited, the
bone regeneration speed is increased, the
bone healing capacity is accelerated, and the
recovery time of a patient is shortened.