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Mass control method of fructus momordicae compound preparations

A quality control method and compound preparation technology, applied in the field of quality control of Luo Han Guo compound preparations, can solve problems such as difficult preparation quality control, too simple quality control method, and low specificity

Inactive Publication Date: 2008-05-21
广西万寿堂药业有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The quality control method in its quality standard is too simple and not very specific, making it difficult to effectively control the quality of the preparation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Monk Fruit Cough Capsules

[0018] Prescription: Luo Han Guo 230g, Loquat leaves 880g, Morus alba 60g, Baiqian 90g, Baibu 150g, Campanulaceae 60g, Peppermint oil 1g, Starch 80g, Talcum powder 3.5g

[0019] Preparation method: take the above seven medicinal materials, take Baibu and Platycodon grandiflorum, and grind them, and take 166g of fine powder for later use. The remaining coarse powder is mixed with Luo Han Guo, loquat leaves, Morus alba, and Baiqian, and decocted twice, the first time for 1.5 hours, and the second time. The second time is 1 hour, the decoction is combined, filtered, the filtrate is concentrated into a thick paste with a relative density of 1.31-1.35 (60-80°C), mixed with the above-mentioned fine powder and starch, made into granules, dried, added peppermint oil, The talc powder is mixed evenly, packed into capsules, and made into 1000 capsules.

[0020] Identification: (1) Take 10 capsules of this product, take the contents, grind fin...

Embodiment 2

[0026] Example 2 Monk Fruit Cough Tablets

[0027] Prescription: with embodiment 1

[0028] Preparation method: same as Example 1, finally pressed into 1000 tablets, coated, to obtain final product.

[0029] Identification: with embodiment 1.

[0030] Content determination: with embodiment 1, each sheet of this product contains Morus alba and scopoletin (C 10 h 8 o 4 ) shall not be less than 1.0 μg.

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PUM

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Abstract

The invention relates to a quality control method of Chinese patent medicine, in particular to a quality control method of grosvenor momordica compound preparation. The invention can conduct effective quality control on the grosvenor momordica anticough tablet and is also suitable for the capsules, soft capsules and pills prepared according to the prescription. Based on the original standard, the quality control method rectifies the discrimination method of lamina of balloonflower root, which uses the water as extract dissolvent and developer instead of aether, and uses ultrasonic extraction instead of reflux extraction, with more covenient and safe operation as well as specialization; the invention adds the content measuring of scopoletin of cortex mori radicis so as to control the quality of grosvenor momordica and the various medicine forms effectively.

Description

field of invention [0001] The invention relates to a quality control method of Chinese patent medicine, in particular to a quality control method of Luo Han Guo compound preparation. Background technique [0002] Luo Han Guo Cough Tablets currently in circulation in the market are oral preparations prepared from seven traditional Chinese medicine raw materials such as Luo Han Guo, loquat leaves, Morus alba, Baiqian, Baibu, Platycodon grandiflorum, and peppermint oil. It has the effect of eliminating phlegm and relieving cough. For the treatment of cold cough and bronchitis. Its quality standards are recorded on page 440 of the "National Compilation of Chinese Patent Standards" Internal Medicine and Pulmonary System (II). The quality control method in its quality standard is too simple and not very specific, making it difficult to effectively control the quality of the preparation. Contents of the invention [0003] The purpose of the present invention is to disclose a ki...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P11/14G01N30/02G01N30/90
Inventor 韦宏官黎德南杨桂芳谭文明
Owner 广西万寿堂药业有限公司
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