Application of hyamine antibiont on dentistry antibacterial replacement material

Abstract

The invention discloses the application of an antibacterial quaternary ammonium salt monomer in dental antibacterial repairing material. The antibacterial quaternary ammonium salt monomer is inserted into a dental resin base material to enable the dental resin base material to have antibacterial property. The general molecular formula is shown in the right, wherein, R1=CH2CH2, R2= CH3, R4= CH3. One end of the structure is bisphenol A metacrylic acid glycidyl ester, carbamate bi-metacrylic acid ester or common polyradical group of the diluted triethylene - glycol dimethacrylate monomer molecule-a metacrylic acid ester group, and the other end is a functional group with antibacterial property, including N+ with positive electric charge, and a benzene ring, a meta- benzene ring and a long alkyl chain which are at the side chain.

Description

technical field [0001] The invention relates to the application of a class of antibacterial monomers, in particular to the application of a class of quaternary ammonium salt type antibacterial monomers for dental antibacterial restoration materials. Background technique [0002] An ideal dental antibacterial restorative material should be soaked in water, oil and other media without any dissolved matter, and the surface of the material can effectively kill harmful bacteria, and at the same time have safety, high efficiency and broad spectrum. The system itself needs to Has good biocompatibility. For more than 30 years, although scholars all over the world have paid great attention to this problem, there are still few technologies that have been widely accepted so far. In summary, these technologies can be divided into the following aspects: [0003] Direct addition of organic antibacterial agents: Additives include natural organic substances and chemically synthesized orga...

AI Technical Summary

Problems solved by technology

For more than 30 years, although scholars all over the world have paid great attention to this problem, there are still few technologies that have been widely accepted so far.

However, the side effects of chlorhexidine can not be ignored, including moderate and severe staining of teeth and soft tissues in some patients, excessive deposition of calculus on the gums, soft tissue damage in young patients, allergies and abnormal taste

[0006] The antibacterial material studied by this method has the advantages of fast onset of action, high antibacterial efficacy, and easy dispersion and mixing, but there are generally two main disadvantages: first, its drug release kinetics show that in the first few days, the antibacterial It is difficult to achieve long-term release of antibacterial ingredients; secondly, the mechanical properties of materials are significantly reduced after adding antibacterial agents

[0009] In China, there is no research report on dental antibacterial polymer materials.

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