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Bactericide for pet and preparation method thereof

A preparation, pet technology, applied in the direction of topical antibacterial agents, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problems of skin irritation and injury, too delicate skin, broken skin, etc. High bactericidal effect and strong killing effect

Inactive Publication Date: 2008-10-22
SHANGHAI HI TECH BIOENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And these problems cannot be controlled by means such as brushing teeth like humans
[0004] At present, the commonly used bactericidal preparations for pet skin and mucous membranes mainly include chemical bactericidal or antibacterial preparations such as alcohol, iodine, potassium permanganate, etc., which will cause different degrees of irritation and damage to the skin, especially not for oral mucosa, ulcerated skin, etc. And too delicate skin, and long-term use will cause drug resistance problems

Method used

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  • Bactericide for pet and preparation method thereof
  • Bactericide for pet and preparation method thereof
  • Bactericide for pet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Make 100 grams of antiseptic preparation

[0056] Proportion:

[0057] Lysostaphin 0.0015g

[0058] Lysozyme 0.2g

[0059] Potassium phosphate 0.2g

[0060] Sodium chloride 0.2g

[0061] Chitin 2g

[0062] Distilled water 97.4g

[0063] Method: In a sterile room, weigh each component according to the above table, add it to a clean glass or stainless steel container in proportion, add sterile distilled water, stir gently, and mix well, then fill in Store in plastic or glass bottles and store at room temperature.

[0064] The preparation can be used for disinfection of skin and mucous membranes of pets, and can kill Neisseria gonorrhoeae, Staphylococcus aureus, Candida albicans, Pseudomonas aeruginosa, Escherichia coli, etc. on the surface of skin and mucous membranes within 2-10 minutes. Up to 99.9%. It can be used to clean and disinfect pet burns, scalds, scratches, bites and other wounds. Spray evenly on the affected area 3 to 4 times a day. It is advisable to ...

Embodiment 2

[0065] Example 2 Bacteria Quantitative Killing Test

[0066] 1. Equipment

[0067] 1. Test strains: Candida albicans (ATCC10231), Escherichia coli (8099), Staphylococcus aureus (ATCC6538), Pseudomonas aeruginosa (ATCC27853). purchased from China Center for Type Culture Collection (CCTCC).

[0068] 2. Test material: the bactericidal preparation prepared in Example 1

[0069] 3. Neutralizer: PBS solution of 0.5 sodium thiosulfate, 2% Tween-80, 0.5% lecithin

[0070] 4. Sterile hard water

[0071] 5. Diluent: (TPS)

[0072] 2. Method

[0073] 1. Inspection basis: Ministry of Health "Disinfection Technical Specifications" (2002 Edition) 2..1.1.7.4 Bacteria Quantitative Killing Test

[0074] 2. Sterilization test: The test temperature is 21°C, and the test is repeated 3 times.

[0075] 3. The killing effect on the test bacteria

[0076] 1. The average killing logarithms against Candida albicans for 2.5 minutes, 5 minutes and 7.5 minutes respectively were >5.00.

[0077] Ta...

Embodiment 3

[0096] Manufacture 100 grams of lysostaphin complex enzyme preparation

[0097] Proportion:

[0098] Lysostaphin 0.001g

[0099] Lysozyme 0.2g

[0100] Chlorhexidine acetate 0.01g

[0101] Potassium chloride 0.15g

[0102] Sodium chloride 0.15g

[0103] Chitosan 1.5g

[0104] Distilled water 97.99g

[0105] Method: In a sterile room, weigh each component according to the above table, add it to a clean glass or stainless steel container in proportion, add sterile distilled water and stir gently, mix well, and fill it in a plastic container. Or in glass bottles, stored at room temperature.

[0106] The bactericidal preparation can be used for cleaning and disinfecting the oral cavity of pets, and can treat various oral diseases, bad breath and the like caused by bacterial infection. It can be sprayed into the pet's mouth with a spray device, or dipped in a cotton ball to wipe the pet's oral tissues including gums, 2-3 times a day, once a day after the symptoms improve. ...

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Abstract

The invention discloses a sterilization preparation used for a pet, which includes effective quantity of lysostaphin and lysozyme for the sterilization. The preparation of the invention is provided with higher sterilizing effect than the lysostaphin and a strong function in sterilizing gram-positive bacteria and gram-negative bacteria, especially strong effect in sterilizing resistant staphylococcus aureus. The sterilization preparation has no stimulation to the skin and mucosa of the pet and the drug resistance can not be produced easily. The sterilization preparation provided by the invention can be used for the sterilization and the disinfection of the body parts of the pet, such as the skin mucosa, etc., which is used for cleaning and the disinfection of wounds caused by burning, scalding, scratching, biting, etc., the debridement and the prevention of infection before and after various surgeries of surgery, gynecology, urological department, stomatology, etc. and the cleaning and the disinfection of the oral, the ear canal and the nose of the pet.

Description

technical field [0001] The invention relates to a biocidal preparation, in particular to a compound lysostaphin preparation for pets and a preparation method thereof. Background technique [0002] While pets bring people fun, they also bring many unexpected problems, such as infectious diseases, allergies, scratches and bites, etc. There are more than 200 kinds of infectious diseases that are zoonotic, and their transmission routes include through the digestive tract, respiratory tract, etc. There are more than 40 kinds of viral, bacterial and parasitic diseases transmitted from dogs to humans by pets. Skin contact is the main route of transmission. The fur of pets is easily contaminated with dust, which causes pathogenic bacteria to breed and multiply in large numbers, and is transmitted to humans through skin contact with humans. [0003] At the same time, the pathogenic bacteria carried on the body of the pet are easy to cause the disease of the pet itself. Such as skin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61K47/34A61K47/36A61K47/16A61P31/04A61P31/02A61K38/02A61K31/58A61K31/352A61K31/155A61K31/122A61K31/045A61K47/10
Inventor 陆婉英
Owner SHANGHAI HI TECH BIOENG
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