Hyper-concentrated placenta nano viable cell freeze-drying capsules and its preparation method

A technology of placenta and living cells, which is applied in capsule delivery, pharmaceutical formulations, medical preparations of non-active ingredients, etc., can solve problems such as insufficient molecular weight, large molecular weight of placenta, and insufficient core components of placenta

Inactive Publication Date: 2012-05-16
陈包容
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the molecular weight of the placenta "actively extracted" by SFE technology is not small enough, and the core components of the placenta finally absorbed and fused by the human body still cannot reach a very high level.
[0005] Therefore, aiming at the problem that the molecular weight of the placenta extracted by SFE technology is still relatively large, the inventor provides a placenta extracted by bionanotechnology (bionanotechnology), the core component of which is made into a particle size of 1 ~ 100nm ultrafine particles

Method used

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  • Hyper-concentrated placenta nano viable cell freeze-drying capsules and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Embodiment 1 The preparation method of ultra-concentrated placenta nano-living cell freeze-dried powder and the capsule it makes

[0056] a) freeze-drying the fresh placenta at -5°C to -6°C for 5 to 6 hours, and grinding it into powder;

[0057] b) Put the obtained placenta powder into an extraction kettle of 11, pass through carbon dioxide of about 30MPa, and extract under the condition of 30-40°C;

[0058] c) Carry out secondary decompression separation, the primary decompression separation condition is operating pressure 8~12MPa, temperature is 30~35 ℃; obtain placenta;

[0059] d) Homogenizing the placenta product obtained by the two-stage decompression separation in sterile water under sterile conditions, centrifuging with a centrifuge at 3500-4000rmp; filtering to obtain the first clear liquid;

[0060] e) Ultrafiltration of the first clear liquid with an ultrafiltration membrane with a molecular weight cut-off of about 3000 Daltons for 1 to 2 times to obtain th...

Embodiment 2

[0068] The use effect of embodiment 2 concentrated placenta nano living cell capsules

[0069] This experiment was carried out with mild progeria as the observation object.

[0070] The first stage: 10 to 20 days after the subject takes the ultra-concentrated placenta nano-living cell freeze-dried capsule encapsulated in a certain unit dose (once a day, one capsule each time).

[0071] In this first stage:

[0072] ●Appearance of the subject: the face is shiny, rosy, and radiant, the skin begins to be moist and hydrated, the skin becomes elastic when pressed by hands, the spots are initially faded, and the wrinkles become lighter.

[0073] ●Physiological manifestations of the subjects: fatigue relief, increased physical strength, vigorous energy, increased appetite, improved sleep with deep sleep, and significantly enhanced sexual function.

[0074] The second stage: 30 to 50 days after the subject takes the ultra-concentrated placenta nano-living cell freeze-dried capsule e...

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Abstract

The invention provides a preparation method of hyperconcentration placental-peptide nanometer viable-cell freeze-dried powder, and a hyperconcentration placental-peptide nanometer viable-cell freeze-dried capsule which comprises the hyperconcentration placental-peptide nanometer viable-cell freeze-dried powder prepared by the preparation method. The preparation method adopts the CO2 supercriticalextraction, the ultra-low-temperature freeze-drying technology, and the biological nanotechnology. The hyperconcentration placental-peptide nanometer viable-cell freeze-dried capsule is obtained by utilizing the lipidosome preparation technology.

Description

technical field [0001] The invention relates to a preparation method of super-concentrated placenta nano-living cell freeze-dried powder and a super-concentrated placenta nano-living cell freeze-dried capsule containing the same. This ultra-concentrated placenta nano live cell freeze-dried capsule is made through liposome technology. Background technique [0002] The placenta Chinese medicine is called Ziheche, which has the functions of regulating human body functions, enhancing resistance, and nourishing vital energy, essence and blood. Placenta is a medicinal ingredient extracted from the placenta, which contains a variety of hormones and biological enzymes. In the past, the extraction of placenta mostly used the method of cooking and concentrating. Through research, the inventor has provided a method for extracting placenta by supercritical carbon dioxide extraction, please refer to Chinese patent 200410096974.0, the placenta extracted by this method has the active com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/50A61K9/127A61K9/48A61K47/32A61K47/36A61K47/38A61K47/42A61P37/02C12P21/00
CPCY02P20/54
Inventor 陈包容
Owner 陈包容
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