Angiogenic tyrosyl trna synthetase compositions and methods
An angiogenesis and enzyme synthesis technology, applied in the field of angiogenic TyrRS protein variants and its angiogenic fragments to stimulate angiogenesis, can solve the problem of no cytokine activity
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[0026] DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
[0027] Amino acid residues in proteins have been classified in different ways, mainly based on the physicochemical characteristics conferred by the amino acid side chains. For example, one general classification includes three classes of amino acids: (1) hydrophobic (nonpolar) amino acids, including glycine, alanine, valine, phenylalanine, proline, methionine, isoleucine, amino acids; (2) charged amino acids, including aspartic acid, glutamic acid, lysine, and arginine; and (3) polar amino acids, including serine, threonine, tyrosine, Histidine, cysteine, asparagine, glutamine, and tryptophan; glycine is sometimes included in the fourth class, by itself (see Chapter 1 of Branden and Tooze, Introduction to Protein Structure, Second Edition, Garland Publishing, Inc. 1998, pages 3-12, which are incorporated herein by reference).
[0028] Amino acid residues can be further classified according to whether their side chains...
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