Medicament compound for treating chronic gastritis and preparation method thereof

A chronic gastritis and drug technology, applied in the field of medicine, can solve the problems of single action target, inability to completely cure chronic gastritis, side effects, etc., and achieve the effect of small dosage, small side effects and good curative effect

Inactive Publication Date: 2009-01-21
LANZHOU UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the drugs for the treatment of chronic gastritis are western medicines. Most of these drugs (such as proton pump inhibitors, histamine H2 receptor antagonists, and selective M1 choline receptor antagonists) start from inhibitin

Method used

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  • Medicament compound for treating chronic gastritis and preparation method thereof
  • Medicament compound for treating chronic gastritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0016] Example 1 Group: Preparation of Compound Extract

[0017] a 100g of Panax notoginseng was crushed and mixed, extracted three times with 6 times the amount of water (34L) to obtain an aqueous extract, concentrated to a density of 1.1-1.2 and spray-dried to obtain a total of 1400g of F1 powder with a yield of 25%.

[0018] (2) Take Codonopsis 700g, Fried Atractylodes 200g, Poria 800g, Licorice 200g, Angelica 300g, Magnolia 600g, Pinellia 600g, Chenpi 600g, Amomum 300g, Yanhu 300g, Astragalus 700g, Citrus aurantium 900g, Huanglian 500g, 100g of Panax notoginseng was crushed and mixed, extracted three times with 6 times the amount of water (41L) to obtain an aqueous extract, concentrated to a density of 1.1-1.2 and spray-dried to obtain a total of 2040g of F2 powder with a yield of 30%.

[0019] (3) Take Codonopsis 700g, Fried Atractylodes 300g, Poria 900g, Licorice 300g, Angelica 400g, Magnolia 700g, Pinellia 700g, Chenpi 700g, Amomum 400g, Yanhu 400g, Astragalus 800g, Ci...

Example Embodiment

[0020] Example Group 2: Preparation of Active Extracts

[0021] (1) get 700g of Codonopsis pilosula, 200g of fried Atractylodes Rhizoma, 300g of Angelica sinensis, 600g of dried tangerine peel, 300g of Amomum officinalis, and 900g of Citrus aurantium pulverized and mixed, pass into steam distillation for extraction for 6 hours, and collect a total of 39g of the oil obtained by distillation, namely active extract A, Yield 1.3%.

[0022] (2) Take 800 g of Poria cocos and 200 g of licorice, mix them after crushing, extract three times with 6 times the volume of 95% ethanol aqueous solution (6 L), take the extract, recover ethanol, concentrate it to a density of 1.1-1.2, spray dry to obtain powdery active substances The total amount of extract B was 120 g, and the yield was 12%.

[0023] (3) Take 600g of Magnolia officinalis, 600g of Pinellia Root, 300g of Yanhu, 700g of Astragalus, 500g of Huanglian, and 100g of Panax notoginseng, crushed and mixed with the residues of medicinal...

Example Embodiment

[0024] Example Group 3: Preparation of Active Extract Compositions

[0025] 7.8 g of active extract A prepared in Example 1 was clathrated with 54.6 g of β-cyclodextrin by grinding method, and the obtained inclusion compound was thoroughly mixed with 24 g of active extract B and 47.6 g of active extract C to obtain an active extract composition. D total 130g.

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Abstract

The invention discloses a medicine for treating chronic gastritis and a preparation method thereof, wherein, the medicine has the ingredients of 7 parts of dangshen, 1-3 parts of parched white atractylodes rhizome, 7-9 parts of tuckahoe, 1-3 parts of liquorice, 2-4 parts of angelica, 5-7 parts of magnolia officinalis, 5-7 parts of pinellia tuberifera, 5-7 parts of dried tangerine peel, 2-4 parts of amomum villosum, 2-4 parts of rhizoma corydalis, 6-8 parts of radix astragali, 8-10 parts of bitter orange, 4-6 parts of goldthread root and 1-3 parts of sanchi; the preparation method is that: (1) the medicine materials are directly ground into powder and prepared into oral preparation according to the conventional pharmacy technique; or (2) the raw material and water are mixed together and decocted so as to prepare the oral preparation by taking the aqueous extract; or (3) the raw material medicine is extracted and purified by a certain method to obtain the composite of active extract, and the oral preparation is prepared according to the conventional pharmacy technique.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a compound Chinese patent medicine for treating chronic gastritis prepared from traditional Chinese medicines. Background technique [0002] Chronic gastritis is chronic inflammation of the gastric mucosa and is also a common disease, the incidence of which increases with age. At present, most of the drugs for the treatment of chronic gastritis are western medicines. Most of these drugs (such as proton pump inhibitors, histamine H2 receptor antagonists, and selective M1 choline receptor antagonists) start from inhibiting the formation of gastric acid. Quickly relieve symptoms such as stomach acid, bloating, and stomach pain, but long-term use is prone to side effects, and these drugs have a single target, so most of them cannot completely cure chronic gastritis. Therefore, the research on traditional Chinese medicine and natural medicine for the treatment of chronic gastritis has been st...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/14A61K9/20A61K9/48A61P1/04
Inventor 杨中铎李涛马建忠王鸣刚
Owner LANZHOU UNIVERSITY OF TECHNOLOGY
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