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Medicament compound for treating chronic gastritis and preparation method thereof
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A chronic gastritis and drug technology, applied in the field of medicine, can solve the problems of single action target, unable to completely cure chronic gastritis, side effects, etc., and achieve the effect of small dosage, small side effects and good curative effect.
Inactive Publication Date: 2012-06-06
LANZHOU UNIVERSITY OF TECHNOLOGY
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Problems solved by technology
At present, most of the drugs for the treatment of chronic gastritis are western medicines. Most of these drugs (such as proton pump inhibitors, histamine H2 receptor antagonists, and selective M1 choline receptor antagonists) start from inhibiting the formation of gastric acid. Quickly relieve symptoms such as stomach acid, bloating, and stomach pain, but long-term use is prone to side effects, and these drugs have a single target, so most of them cannot completely cure chronic gastritis
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Embodiment 1
[0016] Example group 1: preparation of compound extract
[0017] (1) Take Codonopsis 700g, Fried Atractylodes 100g, Poria 700g, Licorice 100g, Angelica 200g, Magnolia officinalis 500g, Pinellia 500g, Tangerine Peel 500g, Amomum 200g, Corydalis 200g, Astragalus 600g, Fructus Aurantii 800g, Huanglian 400g, 100g of Panax notoginseng was crushed and mixed, extracted three times with 6 times the amount of water (34L) to obtain an aqueous extract, concentrated to a density of 1.1-1.2 and spray-dried to obtain a total of 1400g of F1 powder with a yield of 25%.
[0018] (2) Take Codonopsis 700g, Stir-fried Atractylodes 200g, Poria 800g, Licorice 200g, Angelica 300g, Magnolia Bark 600g, Pinellia 600g, Tangerine Peel 600g, Amomum 300g, Corydalis 300g, Astragalus 700g, Fructus Aurantii 900g, Huanglian 500g, 100g of Panax notoginseng was crushed and mixed, extracted three times with 6 times the amount of water (41L) to obtain the water extract, concentrated to a density of 1.1-1.2 and spray-dr...
Embodiment 2
[0020] Example 2: Preparation of active extract
[0021] (1) Take 700g of Codonopsis, 200g of Fried Atractylodes, 300g of Angelica, 600g of Tangerine Peel, 300g of Amomum, 900g of Citrus aurantium, crushed and mixed, pass into steam for extraction for 6 hours, collect a total of 39g of distilled oil, which is active extract A. The yield was 1.3%.
[0022] (2) Take 800g of Poria cocos and 200g of licorice, pulverize, mix, reflux and extract three times with a 6-fold amount of 95% ethanolaqueous solution (6L), take the extract, recover the ethanol, concentrate to a density of 1.1 to 1.2, and spray dry to obtain a powdery activity The total amount of extract B is 120g, and the yield is 12%.
[0023] (3) Take 600g of Magnolia Bark, 600g of Pinellia ternata, 300g of Corydalis, 700g of Astragalus, 500g of Huanglian, 100g of Panax notoginseng and mix it with the medicinal residues extracted in (1) and (2) above, and use 6 times the amount of water (41L) extracted three times to obtain th...
Embodiment 3
[0024] Example 3: Preparation of active extract composition
[0025] 7.8 g of the active extract A prepared in Example 1 was clathrated with 54.6 g of β cyclodextrin by grinding method, and the obtained clathrate was thoroughly mixed with 24 g of active extract B and 47.6 g of active extract C to obtain an active extract composition D is 130g in total.
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Abstract
The invention discloses a medicine for treating chronic gastritis and a preparation method thereof, wherein, the medicine has the ingredients of 7 parts of dangshen, 1-3 parts of parched white atractylodes rhizome, 7-9 parts of tuckahoe, 1-3 parts of liquorice, 2-4 parts of angelica, 5-7 parts of magnolia officinalis, 5-7 parts of pinellia tuberifera, 5-7 parts of dried tangerine peel, 2-4 parts of amomum villosum, 2-4 parts of rhizoma corydalis, 6-8 parts of radix astragali, 8-10 parts of bitter orange, 4-6 parts of goldthread root and 1-3 parts of sanchi; the preparation method is that: (1)the medicine materials are directly ground into powder and prepared into oral preparation according to the conventional pharmacy technique; or (2) the raw material and water are mixed together and decocted so as to prepare the oral preparation by taking the aqueous extract; or (3) the raw material medicine is extracted and purified by a certain method to obtain the composite of active extract, and the oral preparation is prepared according to the conventional pharmacy technique.
Description
Technical field [0001] The present invention relates to the field of medicine, in particular to a compound Chinese patent medicine for treating chronic gastritis prepared by using Chinese medicine as a raw material. Background technique [0002] Chronic gastritis is a chronic inflammation of the gastric mucosa. It is also a common disease, and its incidence increases with age. At present, most of the drugs for the treatment of chronic gastritis are western medicines. These drugs (such as proton pump inhibitors, histamine H2 receptor antagonists, and selective M1 cholinereceptor antagonists) mostly start with inhibiting the formation of gastric acid, although they can It quickly relieves symptoms such as stomach acid, bloating, and stomach pain, but long-term use is prone to side effects, and the target of these drugs is relatively single, so most of them cannot completely cure chronic gastritis. Therefore, research on traditional Chinese medicine and natural medicine for the tr...
Claims
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Application Information
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