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Use of patchouli alcohol in preparing medicament

A technology of potiole alcohol and drugs, which is applied in the field of medicine and can solve the problems of drug resistance and side effects

Active Publication Date: 2009-07-22
DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing drugs not only have side effects, but also drug resistance

Method used

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  • Use of patchouli alcohol in preparing medicament
  • Use of patchouli alcohol in preparing medicament
  • Use of patchouli alcohol in preparing medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] Patchouli is crushed into coarse powder, passed through a 10-mesh sieve, and 2000g is taken, placed in a supercritical extraction device, and CO2 is used for supercritical extraction. The extraction conditions are: extraction pressure 12-30Mpa; extraction temperature 55-60°C; analysis pressure 5 -6Mpa; analysis temperature is 40-45°C, after 2 hours of extraction, patchouli SFE-CO containing patchouli alcohol is obtained 2 Extract, put in a clean container for later use.

[0090] Get the patchouli SFE-CO that above-mentioned makes 2 2000 mg of the extract is added with appropriate auxiliary materials, dissolved in 1000 ml of water to make an aqueous solution, dissolved, mixed evenly, subpackaged into dripping pills with a concentration of 2 mg / 1 ml per branch, sealed and sterilized. During the influenza epidemic, it is used for instillation into the nasal cavity to prevent and treat influenza.

Embodiment 2

[0092] Get the patchouli SFE-CO that embodiment 1 makes 2 200 mg of the extract is added with appropriate auxiliary materials, dissolved in 1000 ml of water to make a 0.2% aqueous solution, dissolved, mixed evenly, sealed and sterilized. During an influenza epidemic, it is used as an injection to prevent or treat influenza.

Embodiment 3

[0094] Get the patchouli SFE-CO that embodiment 1 makes 2 200 mg of the extract is added with appropriate auxiliary materials to form soft capsules containing 5% patchouli alcohol, which are sealed and sterilized. During the influenza epidemic, it is used orally to prevent or treat influenza.

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Abstract

The invention relates to a novel application of patchouli alcohol or cabline patchouli CO2 supercritical extract or cabline patchouli oil in the field of pharmaceutical. The cabline patchouli CO2 supercritical extract or cabline patchouli oil contains patchouli alcohol. The patchouli alcohol has obvious effects of inhibiting and killing influenza A1 virus, influenza B virus and birds influenza virus H5N1.

Description

technical field [0001] The invention relates to the use of patchouli carbon dioxide supercritical extract, patchouli oil or pokichol alcohol in preparing medicines, and belongs to the field of medicine. Background technique [0002] Patchouli, Pogostemon cablin (Blanco) Benth., also known as Patchouli and Patchouli, is a plant of the genus Patchouli in the Labiatae family, a perennial herb, used for whole herbal medicine. It is native to subtropical regions such as the Philippines in Asia, and is mainly produced in Guangdong, Hainan and other places in my country. Its taste is pungent, slightly warm, and it returns to the spleen, stomach, and lung meridians. It has the effects of aromatizing turbidity, appetizing, relieving heat, etc. It is mostly used for dampness and turbidity, nausea, vomiting, fatigue due to heat-dampness, chest tightness and discomfort, cold-dampness blocking heat, abdominal pain, vomiting and diarrhea, and nasal sinusitis headache. The medicinal ingr...

Claims

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Application Information

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IPC IPC(8): A61K31/045A61K36/53A61P31/16
CPCA61K31/045A61K36/53A61P31/16
Inventor 赖小平苏子仁张奉学彭绍忠胡家敏
Owner DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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