Cefixime sustained-release tablets and preparation method thereof

A technology of cefixime and sustained-release materials, which is applied in the direction of pharmaceutical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve the difficulty of industrialization and the cumbersome preparation process of cefixime sustained-release tablets And other issues
CN101496791AInactive Publication Date: 2009-08-05SHANDONG BESTCOMM PHARMA CO LTD
2 Cites 10 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANDONG BESTCOMM PHARMA CO LTD
Publication Date
2009-08-05
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a slow-release tablet prepared from cefixime and pharmaceutically acceptable auxiliary materials. The slow-release tablet is characterized in that: the slow-release tablet consists of the following raw materials and auxiliary materials in portion by weight: 200 portions of cefixime(counted as an anhydride), 20 to 200 portions of at least one pharmaceutically acceptable slow-release material which can control the drug to continuously and completely release, 20 and 400 portions of a pharmaceutically acceptable excipient and 5 to 100 portions of at least one solubilizer which can effectively improve the release rate of the drug. The slow-release tablet is easy to prepare and facilitates the industrialized production.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations. More specifically, the present invention relates to a sustained-release monolayer tablet of cefixime and a preparation method thereof. Background technique

[0002] The chemical name of Cefixime is (6R, 7R)-7-[(Z)-2-(2-amino-4-thiazolyl)-2-(carboxymethoxyimino)acetamide]-8 -Oxy-3-ethylene-5-thio-1-azabicyclo[4,2,0]octa-2-ene-2-carboxylic acid trihydrate. It is a white to light yellow crystalline powder, odorless or slightly special smell, easily soluble in methanol, slightly soluble in ethanol and water, insoluble in chloroform and ether.

[0003] Cefixime is the third generation of oral cephalosporin antibiotics. It exerts antibacterial activity by inhibiting the synthesis of bacterial cell walls. It has the advantages of broad spectrum, high efficiency, wide distribution in the body, strong tissue penetration, and stability to β-lactamase. It is suitable for infections caused by St...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More