Method for preparing medical high-activity silicon oil

Abstract

The invention discloses a method for preparing medical high-activity silicon oil, which comprises the following steps: using aminopropyl tetramethyldisiloxane, octamethylcy-clotetrasiloxane (D4), tetramethyltetraethylcyclotetrasiloxane(D4), and methylphenyl cyclic body(Dn) as polymeric monomers, and removing a heat source by dynamic ultra-filtration technology under the protection of N2; controlling reaction temperature and reaction time and carrying out polymerization under the actions of a catalyst and an accelerant; after the completion of the reaction, extracting low-boiling-point substances at reduced pressure; and finally, raising temperature and adding an amino coupling agent to obtain a target product with high purity. The method has the advantages of low cost, mild conditions, simple process and operation, no pollution and convenient industrialization. The product prepared by the method is used for the silicatization of medical appliance and has the advantages of excellent lubricating performance, waterproof performance and the like.

Description

technical field [0001] The invention relates to a preparation method of medical high-activity silicone oil. Background technique [0002] In my country's medical device industry, especially the siliconization treatment effect of disposable syringes, injection needles, scalpels and other products directly affects the final use performance of the product. Common silicone oils have the following disadvantages when used in siliconized medical devices: 1. The sliding performance is not good, especially It has basically no lubricating effect on medical supplies such as plastics and rubber; 2. It has poor adhesion on the surface of medical devices; 3. It cannot meet the biological performance requirements of medical devices. The serious consequences brought about by this are: not only can my country's medical devices not be exported to developed countries such as Europe and the United States in large quantities, but they are also used in various domestic medical institutions. Due to...

AI Technical Summary

Problems solved by technology

[0002] In my country's medical device industry, especially the siliconization treatment effect of disposable syringes, injection needles, scalpels and other products directly affects the final use performance of the product. Common silicone oils have the following disadvantages when used in siliconized medical devices: 1. The sliding performance is not good, especially It has basically no lubricating effect on medical supplies such as plastics and rubber; 2. Poor adhesion on the surface of medical devices; 3. Cannot meet the biological performance requirements of medical devices

The serious consequences brought about by this are: not only can my country's medical devices not be exported to developed countries such as Europe and the United States in large quantities, but they are also used in various domestic medical institutions. Due to poor lubrication, it brings a lot of work to medical staff. Inaccurate drug dosage, unsmooth puncture, etc., also brought unnecessary pain to the treatment of the majority of patients

Although there are silicone oils for siliconized syringes in foreign countries, they cannot solidify and form a film at room temperature, and remain liquid on the inner wall of the syringe, and sometimes dissolve in the drug, bringing adverse consequences to the treatment of patients.

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