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Method for screening qi and blood circulation promotion Chinese medicament components

A screening method and technology of traditional Chinese medicine, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, plant/algae/fungus/moss components, etc., can solve problems such as no substantial progress, no treatment measures, neglect, etc., to achieve The process is fast and the results are judged intuitively

Inactive Publication Date: 2010-03-31
BEIJING UNIV OF AGRI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Up to now, there is no research or report on how to measure the function of "flowing qi and blood" of meridians and how to judge the regulating effect of traditional Chinese medicine on it.
[0003] The theory of modern (veterinary) medicine basically belongs to the category of allopathic medicine, and there are two fatal flaws in allopathic medicine: 1. There is no effective treatment for diseases with unknown pathogenic factors or targets; Due to the extensive molecular homogeneity between cells and normal cells, therapeutic drugs developed under the guidance of modern medical theory cannot avoid their toxic and side effects at all
The flaw of this theory is that it ignores the formation of a set of structures to maintain the cellular environment in the long evolution of living organisms, and ignores the decline or loss of the structure's ability to resist damage from pathogenic factors, which leads to the imbalance of the cellular microenvironment, which is the root cause of diseases The reason, ignoring the measures to treat diseases by improving the structure and its function and then improving the cellular microenvironment
However, after more than half a century of modern scientific research on Chinese (veterinary) medicine, not only has there been no substantial progress, no new (veterinary) medicine with clear mechanism and definite composition has been obtained, and it is not only important to modern (veterinary) medicine. There is no major promotion of development, but it has attracted voices opposing the existence of traditional Chinese medicine

Method used

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  • Method for screening qi and blood circulation promotion Chinese medicament components
  • Method for screening qi and blood circulation promotion Chinese medicament components
  • Method for screening qi and blood circulation promotion Chinese medicament components

Examples

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Effect test

Embodiment 1

[0044] A method for screening traditional Chinese medicine ingredients of "promoting qi and blood", using a laser Doppler microvascular function tester combined with an iontophoresis instrument to screen out Chinese medicine ingredients that can increase the amplitude of microvascular diastolic activity through acupoints. The steps included in the screening method are as follows:

[0045] I. Identify acupuncture points:

[0046] Select the test acupoints to be introduced into the traditional Chinese medicine components, and then determine the test acupoints on the test animals with the conventional positioning method of traditional Chinese medicine and veterinary medicine, and finally determine the precise position of the acupoints with a low-resistance acupoint detector, and mark them;

[0047] The selection method is as follows: according to the meridians of the original medicines to which the Chinese medicine ingredients belong, the test points to be imported into the Chine...

Embodiment 2

[0099] The screening method of the "promoting qi and blood" Chinese medicine composition described in this embodiment is the same as that of Example 1, and the instruments, equipment, and reagents used in this example are the same as those of Example 1; the Chinese medicine composition used in this example is Matrine, quality and source are identical with embodiment 1.

[0100] The matrine described in this example is one of the ingredients of the traditional Chinese medicine Sophora flavescens; Sophora flavescens is bitter and cold in nature; Guixin, liver, stomach, large intestine and bladder meridians, so the test points in this example are the front of the large intestine meridian. Sanli acupoint; the selection method of this acupoint is the same as in Example 1.

[0101] In this example, if Figure 9 As shown, the intradermal blood flow in the acupoint area increased 5 minutes after the introduction of matrine, and it was intuitively shown that the blood flow change rang...

Embodiment 3

[0103] The screening method of the "promoting qi and blood" Chinese medicine composition described in this embodiment is the same as that of Example 1, and the instruments, equipment, and reagents used in this example are the same as those of Example 1; the Chinese medicine composition used in this example is Chlorogenic acid, quality and source are identical with embodiment 1.

[0104] The chlorogenic acid described in this example is one of the components of the traditional Chinese medicine honeysuckle, honeysuckle is sweet and cold in nature; it belongs to the lung, stomach, and large intestine meridian, so the test point in this example is the Qiansanli point in the large intestine meridian; The selection method of acupoints is the same as in Example 1.

[0105] In this example, if Figure 10 As shown, the intradermal blood flow in the acupoint area increased after chlorogenic acid was introduced for 5 minutes, and it was intuitively shown that the blood flow change range...

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Abstract

The invention belongs to the field of screening Chinese medicament components, and specifically relates to a method for screening 'qi and blood circulation promotion' Chinese medicament components. The method screens out the Chinese components capable of improving the micro-vascular vasomotion amplitude in a Chinese medicament through acupuncture points by using a laser Doppler micro-vascular function tester combined with an iontophoresis apparatus, and comprises the following steps in turn: determining the acupuncture points; introducing the medicament; measuring data; and collating analysisdata. The method screens out various Chinese medicament components which have the function of improving the intracutaneous micro-vascular vasomotion amplitude of correlative channels and points, and have extensive pharmacological actions. The method is originated from the breakthrough of a channel and point essence and an acupuncture mechanism, and the technical scheme of the method is significantly different from the existing researches and techniques; the method can also be directly used for finding out whether water extracts of a Chinese medicament and a Chinese medicament formula have thefunction of promoting the qi and blood circulation in addition to screening the qi and blood circulation promotion Chinese medicament components; and the processes of screening the medicament are quick and have no wounds, and the result judgment is intuitional.

Description

technical field [0001] The invention belongs to the field of screening of traditional Chinese medicine components, and in particular relates to a method for screening traditional Chinese medicine components of "promoting qi and blood". The invention uses a laser Doppler microvascular function tester combined with an iontophoresis instrument to screen out Chinese medicines with the ability to improve microvascular relaxation and contraction through acupoints. Active amplitude of traditional Chinese medicine components; the screening method includes the steps of: determining acupuncture points, introducing medicines, measuring data, sorting and analyzing data. Background technique [0002] Enhancing the function of "promoting qi and blood" in meridians is the biggest feature and advantage of traditional Chinese medicine in treating diseases. Most of the traditional Chinese medicines recorded in ancient medical books have the function of "promoting qi and blood". But up to now,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/00A61B5/026A61K36/00
Inventor 穆祥索占伟张涛段慧琴陈武胡格董虹
Owner BEIJING UNIV OF AGRI
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