Application of n-butyl alcohol extract of combination of ophiopogon decoction and thousand gold pieces phragmites decoction in preparing medicaments for inhibiting A549 cell proliferation

A technology of n-butanol extract and Ophiopogon decoction, applied in the direction of drug combination, medical preparations containing active ingredients, antitumor drugs, etc., can solve the problem of poor curative effect, unsatisfactory effect of radiotherapy and high drug resistance question
CN101708296AInactive Publication Date: 2010-05-19NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Publication Date
2010-05-19
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses application of an n-butyl alcohol extract of a combination of ophiopogon decoction and thousand gold pieces phragmites decoction in preparing medicaments for inhibiting A549 cell proliferation. In the invention, the n-butyl alcohol extract of the combination of the ophiopogon decoction and the thousand gold pieces phragmites decoction can remarkably inhibit the growth of lung adenocarcinoma cell A549, and has no obvious influence on normal cells of a human body. Because the extract part has a cytotoxic effect, components and monomer compound used for inhibiting the lung adenocarcinoma cell A549 can be further separated and selected.
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Description

technical field

[0001] The invention relates to a traditional Chinese medicine extract and its application, in particular to the application of the n-butanol extract of Maimendong Decoction and Qianjin Weijing Decoction in the preparation of drugs for inhibiting A549 cell proliferation. Background technique

[0002] Lung cancer is one of the common malignant tumors in all countries in the world. It is the fastest growing among all malignant tumors. It is the main cause of human cancer death and is considered to be the most harmful malignant tumor to human health and life in the world today. About 3 million new cases are added every year in the world, and at the same time, more than 1 million people die of lung cancer every year. In my country, lung cancer accounts for the first place in the incidence and death of malignant tumors, with an annual incidence of 35 cases per 100,000 people and a 5-year survival rate of only 10%. Male lung cancer ranks first, while China ranks fi...

Claims

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