This invention relates to a novel compound derived from
nutmeg and an anticancer composition comprising the same. The present invention isolates several novel compounds derived from
nutmeg extract and confirms that most of these novel compounds exhibit cytotoxic activity against various
cancer cell lines. Five compounds (3, 4, 6, 9, and 11) were identified as having high cytotoxic activity against gastric and colorectal cancers. In particular, the compound represented by
chemical formula 3 was confirmed to not only effectively induce
apoptosis by regulating the
cell cycle of
cancer cells but also effectively inhibit
tumor growth in xenograft mouse models, thus making it an effective anticancer composition.