Application of hyperin in preparation of medicament for treating diabetes
A diabetes drug, the technology of hyperoside, applied in the field of biomedicine, can solve the problem of hyperoside that has not yet been seen
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Embodiment 1
[0017] Embodiment 1 hypoglycemic pharmacodynamic experiment
[0018] 1 material
[0019] 1.1 Experimental animals: adult Kunming male mice, weighing 20±2g
[0020] 1.2 Drugs and reagents
[0021] Hyperin drug preparation: take 500mg of powder and dissolve in 20ml of distilled water. Positive drug: Jiangtangling (phenformin tablet), 250mg / tablet. When in use, take 1 tablet (250mg) of Jiangtangling, grind it into pieces, and add water to 30ml. Alloxan: HONG KONG FARC0Chemical Supplies product batch number 42011-3E; blood glucose kit: product of Zhongsheng Beikong Biotechnology Co., Ltd., batch number 24011; SOD kit: product of Nanjing Jiancheng Bioengineering Research Institute, batch number 20030123; MDA kit : product of Nanjing Jiancheng Institute of Bioengineering, batch number 20030107; rabbit anti-mouse Insulin immunohistochemical staining kit: product of Tianjin Haoyang Biological Products Technology Co., Ltd.
[0022] 1.3 Main instruments
[0023] Finnish MK-3 micro...
Embodiment 2
[0035] Example 2 Clinical Observation of 30 Cases of Diabetes Treated by Hyperin Capsules
[0036] 1. Clinical data
[0037] 1.1 General Information
[0038] A total of 30 cases, including 18 males and 12 females; aged 13-73 years, with an average age of 51.55 years, the course of the disease is half a month to 12 years, with an average of 5.23 years
[0039] 1.2 Diagnosis and case selection criteria
[0040] 30 cases of diabetic patients, including 4 cases of type I diabetes and 26 cases of type II diabetes. The selected cases were diabetic patients poorly controlled by simple diet control, exercise therapy and drug therapy (including oral hypoglycemic agents and insulin).
[0041] 2. Treatment method
[0042] 2.1 The main ingredients of the drug
[0043] Hyperin Capsules (Containing Hyperin 50mg / capsule)
[0044] 2.2 Treatment methods
[0045] On the basis of diet and exercise therapy, the original dosage remains unchanged. Take hyperoside capsules 2 capsules / time, 3 / ...
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