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Five-layer coextrusion transfusion medicine packing film and manufacturing method thereof

A technology for packaging and pharmaceuticals, applied in the direction of transportation and packaging, packaging, wrapping paper, etc.

Active Publication Date: 2014-06-18
NANJING OTSUKA TECHBOND TECHNO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008](4) The particle dissolution is extremely low, which is lower than any glass.
[0015] Non-PVC multi-layer co-extruded infusion drug packaging films irradiated by electron beams have similar problems to PVC packaging materials: 1. A large amount of surfactants produced potential hazard to human health
2. After electron beam irradiation, an insoluble and infusible network structure is formed, which is not easy to decompose and cannot be recycled. It can only be solved by burning, which will cause great harm to the environment

Method used

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  • Five-layer coextrusion transfusion medicine packing film and manufacturing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] The thickness of layer A is 10 μm, and the polyester is Ecdel 9965 produced by Eastman.

[0052] The thickness of layer B is 8 μm, and the constituent material is BYNEL2714 of DuPont Company, and the resin blended with it is Engage8003 of Dow, and the blending ratio is 90:10.

[0053] The thickness of layer C is 75 μm, the content of polypropylene is 30%, the content of polyethylene is 50%, and the content of SEBS is 20%. The PP material is Atofina's Z8453, the PE is Dow's Engage8003, and the suitable SEBS material is Kraton's G1650.

[0054] The layer D has a thickness of 90 μm, a polypropylene content of 60%, a polyethylene content of 30%, and a SEBS content of 10%. The PP material is Atofina's 3281, the PF is Versify2200, and the SEBS material is Kraton's G1652.

[0055] The thickness of the E layer is 15 μm, the content of polypropylene is between 75%, and the content of SEBS is 25%. The propylene / ethylene copolymer is Atofina's Z8453, and the SEBS material is Kr...

Embodiment 2

[0057] The thickness of layer A is 15 μm, and the polyester is soft polyester CP301 produced by Mitsubishi.

[0058] The thickness of layer B is 10 μm, and the constituent material is Orevac 18760 of Arkema, and the resin blended with it is Zales 7023 of Mitsubishi, and the blending ratio is 70:30.

[0059] The thickness of layer C is 70 μm, the content of polypropylene is 30%, the content of polyethylene is 50%, and the content of SEBS is 20%. The PP material is Mitsubishi's ZalesMC742, the PE is Dow's Engage8003, and the SEBS material is Kraton's G1651.

[0060] The layer D has a thickness of 95 μm, a polypropylene content of 60%, a polyethylene content of 30%, and a SEBS content of 10%. The PP material is Adflex Q100F of Basel1, the PE is Infuse9100, and the SEBS material is G1650 of Kraton.

[0061] The thickness of the E layer is 15 μm, the content of polypropylene is between 75%, and the content of SEBS is 25%. The propylene / ethylene copolymer is Adsyl 3C30F of Basell...

Embodiment 3

[0063] The thickness of layer A is 12 μm, and the polyester is Ecdel 9967 produced by Eastman.

[0064] The thickness of layer B is 10 μm, and the constituent material is Arkema's Orevac8760, and the resin blended with it is Basell Adflex Q100F, and the blending ratio is 75:25.

[0065]The thickness of layer C is 75 μm, the content of polypropylene is 70%, the content of polyethylene is 15%, and the content of SEBS is 15%. The PP material is Mitsubishi's Zales7023, the PE is Dow's Engage8003, and the SEBS material is Kraton's G1650.

[0066] The layer D has a thickness of 80 μm, a polypropylene content of 65%, a polyethylene content of 25%, and a SEBS content of 10%. The PP material is Atofina's 6232, the PE is Exceed2018CA, and the SEBS material is Kraton's G1675.

[0067] The thickness of the E layer is 20 μm, the content of polypropylene is between 75%, and the content of SEBS is 25%. The propylene / ethylene copolymer is Atofina's Z8453, and the SEBS material is Kraton's ...

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Abstract

The invention relates to a five-layer coextrusion transfusion medicine packing film. The five layers have the materials and the structure that the layer A is the outer layer of a product and is made of polyester or copolyester with the thickness of 10-30 Mum, the layer B is the secondary outer layer of the product and is made of acid modified polyolefin copolymer or the mixture thereof with the thickness of 3-15 Mum, the layer C is the middle layer of the product and is made of the mixture of polyethylene, polypropylene and SEBS with the thickness of 30-80 Mu m, the layer D is the secondary inner layer of the product and is made of the mixture of polyethylene, polypropylene and SEBS with the thickness of 40-110 Mu m, and the layer E is the inner layer of the product and is made of the mixture of co-polypropylene and SEBS with the thickness of 10-40 Mu m. The transfusion medicine packing film is transparent and highly flexible, can be sterilized at high temperature, the outer layer can be printed permanently with conventional pigments and has the functions of impact resistance and abrasion prevention. The inner layer can simply be bonded via heat seal without electron beam irradiation or any additives, and has lower water vapor permeability and oxygen and nitrogen penetration amount. The invention also discloses a manufacturing method of the film.

Description

Technical field [0001] The invention involves the packaging film for infusion drugs. Specifically, it is a five -layer co -squeezing drug packaging film and its manufacturing method. technical background [0002] With the continuous improvement of science and technology, the materials and containers used in drug packaging are also undergoing huge changes. The packaging materials used in large -capacity injection from decades ago have gradually developed to the current polypropylene, polyethylene and other plastic plastics.And their various combinations, the form of packaging has also developed from a single type to coexistence of bottles and bags, and new packaging forms are also being developed.Plastic soft packaging infusion has the advantages of light quality, not easy to break, easy to mold and facilitate various design. It is more in line with the requirements of modern industrial production, which meets the requirements of clinical use of safety and convenient medication, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B32B27/08B65D65/40C08L67/00C08L23/08C08L23/12C08L23/06C08L53/02C08L23/14
Inventor 唐劲松秦川
Owner NANJING OTSUKA TECHBOND TECHNO
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