Method for synthesizing PE (Phosphatidyl Ethanolamine)

A technology for synthesizing phosphatidylethanolamine and phosphatidylethanolamine, which is applied in the direction of phosphorus organic compounds, can solve the problems of low yield, large by-products, and unsuitability for industrial production, and achieve the effects of cost reduction, simple operation, and easy industrial production
CN101805367AActive Publication Date: 2010-08-18EAST CHINA NORMAL UNIVERSITY +2
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
EAST CHINA NORMAL UNIVERSITY
Publication Date
2010-08-18

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Abstract

The invention provides a method for synthesizing PE (Phosphatidyl Ethanolamine), which comprises the following steps of: (a) carrying out a reaction of a compound I and sodium azide to obtain a compound II; and (b) hydrogenating the compound II to obtain the PE. The invention has short synthesis path, simple and convenient operation, low cost, high yield and easy industrial production.
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Description

technical field

[0001] The invention relates to the technical field of compound preparation, and more specifically refers to a method for synthesizing phosphatidylethanolamine. Background technique

[0002] Phosphatidylethanolamine (PE) is an important class of phospholipid compounds. Its application was relatively early in the fields of food processing and health product research. With the continuous progress of research, especially high-purity phosphatidylethanolamine (PE) With the improvement of the preparation method, phosphatidylethanolamine (PE) is gradually applied to the field of pharmaceutical preparations. In the most active field of liposome technology today, high-purity phosphatidylethanolamine (PE) is not only an important raw material for liposome technology One of them, and its derivatives are showing increasing academic value and application value.

[0003] Currently, the synthesis literature of phosphatidylethanolamine is reported by F.S.Roodsari, D.P.Wu, G...

Claims

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