American cockroach medicinal composition for curing oral ulcers and preparation method thereof
A technology of Periplaneta americana and oral ulcer, which is applied in the field of medicine, can solve the problems of poor curative effect of oral ulcer, and achieve the effect of improving curative effect and simple preparation method
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[0028] The preparation method of the American cockroach pharmaceutical composition for treating oral ulcers includes the following steps:
[0029] ①. Preparation of American cockroach extract:
[0030] a. Coarse crushing: pulverize the dried American cockroach to obtain coarse powder of American cockroach for use;
[0031] b. Soaking: Soaking: add 3 to 5 times the amount of water for every 100 kg of coarse powder, soak for 0.5 to 2 hours at a temperature of 70-78°C to prepare a coarse powder mixture for use; among them, the preferred solution is: The amount of water added is 4 times the amount, the soaking time is 1 hour, and the soaking temperature is 74°C;
[0032] c. Three extractions: the coarse powder mixture is extracted three times by decoction. When the coarse powder mixture is extracted for the first time, the extraction time is 7-9 hours; then it is added to the remaining liquid after the first extraction After adding 2 to 4 times the amount of the remaining liquid, the sec...
Example Embodiment
[0042] Example 1
[0043] According to the above method, the dried American cockroach was coarsely crushed, and 300Kg of water was added to every 100Kg of coarse powder. After soaking for 0.5 hours, the temperature was about 70℃, and the extraction was performed three times, the first time was 7 hours; the second time was 200Kg of water, and the extraction 5 hours; add 200Kg of water for the third time and extract for 3 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.05~1.08 (70℃), add 93% w / w ethanol to make it contain alcohol The amount is 40%, keep stirring at 70℃ for 20 minutes, let stand for 10 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, and recover ethanol from the filtrate, concentrate under reduced pressure to a relative density of 1.15~1.18 (70℃), and concentrate to A paste with a moisture content of ≤ 25% can obtain the extract of Periplaneta americana for use; add the active ing...
Example Embodiment
[0044] Example 2
[0045] According to the above method, the dried American cockroach is roughly crushed, and 500Kg of water is added to each 100Kg of coarse powder. After soaking for 2 hours, the temperature is about 78°C. Extract three times, the first time is 9 hours; the second time 400Kg of water is added to extract 7 hours; add 400Kg of water for the third time and extract for 5 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.22~1.25 (90℃), add ethanol with a concentration of 97% w / w to make it contain alcohol The amount is 55%, the temperature is kept at 90℃ and stirred for 40 minutes, and it is allowed to stand for 14 hours. The upper layer of grease is discarded, the lower layer of drug solution is filtered, the filtrate recovers ethanol, and it is concentrated under reduced pressure to a relative density of 1.27~1.30 (90℃). A paste with a moisture content of ≤ 35% can obtain the extract of Periplaneta americana, which i...
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