High-efficiency dry powder inhaler for medicament delivery and medicament delivery method thereof

Abstract

The invention discloses a high-efficiency dry powder inhaler for medicament delivery and a medicament delivery method thereof, and relates to the technical field of medical equipment. The dry powder inhaler is characterized in that: a center island is arranged between a central groove of an upper cover body and a central groove of a lower cover body and the center island, the upper cover body and the lower cover body are compressed and connected into a whole to form a primary air inlet, a lower channel, a lower auxiliary air inlet, an air intake channel, a symmetrical channel, an upper auxiliary air inlet, an air duct, an upper channel and an air outlet, the front end of the center island arranged at the bottom of the air intake channel, the rear end of the center island arranged at the bottom of the air duct; and the lower channel, the symmetrical channel, the lower auxiliary air inlet, the upper auxiliary air inlet and the upper channel are communicated with one another. The method comprises the following steps of: putting a suction nozzle in the mouth; inhaling after an anther sac is put at the lower end of the main air inlet so as to make medicinal powder enter the lower channel after the medical powder passes through the main air inlet; scattering a gas-medicament mixture with the airflow of the lower auxiliary air inlet through the shearing and impact when the gas-medicament mixture reaches the front end of the center island; scattering the gas-medicament mixture with the airflow of the upper auxiliary air inlet again through the shearing and impact when the gas-medicament mixture reaches the rear section of the center island; scattering the gas-medicament mixture again when the gas-medicament mixture reaches the rear end of the center island, then mixing to form appropriate aerodynamic-size particles and sending the particles to the scheduled position of the patient. The dry powder inhaler of the invention is used for the patient to inhale the medicament.

Description

technical field [0001] The invention relates to a high-efficiency dry powder inhaler for drug delivery and a drug delivery method thereof, and relates to the technical field of medical devices; in particular, it relates to the technical field of medical devices whose main part adopts the design of a non-moving single part. Background technique [0002] Dry powder inhaler is a medical device that directly transmits drugs to the respiratory system, passes through the mucosal tissue of the respiratory system, and then acts on the target tissues of the human body to achieve rapid and effective inhalation drug delivery. Due to the direct, convenient, fast and efficient features of dry powder inhalers, hundreds of inhalers with different design ideas have been used in the medical field since their launch in the 1970s. But so far, its ubiquitous deficiencies, defects and drawbacks are summed up as follows: 1. Cannot effectively control the aerodynamic size of suitable medicated pow...

AI Technical Summary

Problems solved by technology

However, micron-sized ultrafine powders are easy to agglomerate, and conventional dry powder inhalers cannot effectively disperse the agglomerated ultrafine powders into particles between 0.5-5 microns and with suitable aerodynamic size, so the particle size will be too large. However, it is deposited in the nasal cavity, throat, bronchus and other parts, and cannot reach the preset administration sites such as the deep lung

The lung delivery efficiency of most products on the market is about 10%. This low efficiency of drug delivery usually results in a lot of waste of drug ingredients

② Due to the differences in lung function of individual patients, it is impossible to provide sufficient powder doses for those with weak lung function

③. The dry powder inhaler is composed of multiple parts (especially moving parts), and its flow resistance cannot be stably controlled

This unstable flow resistance leads to the fact that the actual inhaled airflow cannot reach the stable gas flow required by the design, resulting in inaccurate and unstable doses of the actual inhaled powder; at the same time, there are cumbersome operations, inconvenient use, and complicated assembly procedures. Common problems with high cost

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