High-efficiency dry powder inhaler for medicament delivery and medicament delivery method thereof

A dry powder inhaler and inhaler technology, applied in the field of medical devices, can solve problems such as complicated assembly procedures, instability, and inconvenient use, and achieve the effects of being easy to be widely popularized and applied, with stable and reliable effects, and simple and easy methods

Inactive Publication Date: 2010-10-13
于清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, micron-sized ultrafine powders are easy to agglomerate, and conventional dry powder inhalers cannot effectively disperse the agglomerated ultrafine powders into particles between 0.5-5 microns and with suitable aerodynamic size, so the particle size will be too large. However, it is deposited in the nasal cavity, throat, bronchus and other parts, and cannot reach the preset administration sites such as the deep lung
The lung delivery efficiency of most products on the market is about 10%. This low efficiency of drug delivery usually results in a lot of waste of drug ingredients
② Due to the differ

Method used

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  • High-efficiency dry powder inhaler for medicament delivery and medicament delivery method thereof
  • High-efficiency dry powder inhaler for medicament delivery and medicament delivery method thereof
  • High-efficiency dry powder inhaler for medicament delivery and medicament delivery method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

Specific implementation mode two

[0045] Carry out on the basis of specific implementation mode 1, as the description attached Figure 4 Shown: Only the upper cover and the lower cover are provided with an olive-shaped central half-cavity, and the inner wall of the half-cavity is longitudinally provided with a groove connected to the lower channel at the lower end and connected to the upper channel groove at the upper end The structure of the groove is also provided with an olive-shaped three-dimensional structure for the central island 17 and the mixing zone 3; the expected good effect is also obtained.

Example Embodiment

Specific implementation mode three

[0046] Implement on the basis of the implementation of the specific implementation mode one and two:

[0047] A high-efficiency dry powder inhaler for drug delivery, comprising a main body structure of the inhaler, and accessories such as a drug bag, a drug cartridge or an indentation and its fixing device, and a mouthpiece cover for storing drug powder.

[0048]The main structure of the inhaler includes at least one main air inlet, at least one auxiliary air inlet, at least one mixing area, at least one air flow channel structure, and at least one air outlet, and at least one central island structure is arranged inside the mixing area.

[0049] The main air inlet is used to introduce the drug powder stored in the drug bag, cartridge or concave bubble into the main body of the inhaler under the action of the airflow generated by the patient's spontaneous inhalation;

[0050] The auxiliary air inlet is used to introduce the airflow generated...

Example Embodiment

Specific implementation mode four

[0062] Carry out implementation on the basis of the implementation of specific implementation modes 1 and 2, and focus on referring to the instructions attached figure 2 , a drug delivery method of a high-efficiency dry powder inhaler for drug delivery, adopting serial numbers to describe the overall implementation of the continuous and organically integrated method process: ①. Applying the high-efficiency dry powder inhaler for drug delivery (hereinafter referred to as the inhaler); 2., remove the mouthpiece cover on the inhaler, the patient will contain the mouthpiece 4 of the inhaler in the mouth, and place the medicine bag 8 that is stored with the powder and opens the opening into the main air inlet of the inhaler 1 lower end; ③, when the patient actively inhales, under the action of the airflow of the patient’s active inhalation, the agglomerated drug powder particles 9 in the medicine bag 8 enter the inhalation through the main air in...

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Abstract

The invention discloses a high-efficiency dry powder inhaler for medicament delivery and a medicament delivery method thereof, and relates to the technical field of medical equipment. The dry powder inhaler is characterized in that: a center island is arranged between a central groove of an upper cover body and a central groove of a lower cover body and the center island, the upper cover body and the lower cover body are compressed and connected into a whole to form a primary air inlet, a lower channel, a lower auxiliary air inlet, an air intake channel, a symmetrical channel, an upper auxiliary air inlet, an air duct, an upper channel and an air outlet, the front end of the center island arranged at the bottom of the air intake channel, the rear end of the center island arranged at the bottom of the air duct; and the lower channel, the symmetrical channel, the lower auxiliary air inlet, the upper auxiliary air inlet and the upper channel are communicated with one another. The method comprises the following steps of: putting a suction nozzle in the mouth; inhaling after an anther sac is put at the lower end of the main air inlet so as to make medicinal powder enter the lower channel after the medical powder passes through the main air inlet; scattering a gas-medicament mixture with the airflow of the lower auxiliary air inlet through the shearing and impact when the gas-medicament mixture reaches the front end of the center island; scattering the gas-medicament mixture with the airflow of the upper auxiliary air inlet again through the shearing and impact when the gas-medicament mixture reaches the rear section of the center island; scattering the gas-medicament mixture again when the gas-medicament mixture reaches the rear end of the center island, then mixing to form appropriate aerodynamic-size particles and sending the particles to the scheduled position of the patient. The dry powder inhaler of the invention is used for the patient to inhale the medicament.

Description

technical field [0001] The invention relates to a high-efficiency dry powder inhaler for drug delivery and a drug delivery method thereof, and relates to the technical field of medical devices; in particular, it relates to the technical field of medical devices whose main part adopts the design of a non-moving single part. Background technique [0002] Dry powder inhaler is a medical device that directly transmits drugs to the respiratory system, passes through the mucosal tissue of the respiratory system, and then acts on the target tissues of the human body to achieve rapid and effective inhalation drug delivery. Due to the direct, convenient, fast and efficient features of dry powder inhalers, hundreds of inhalers with different design ideas have been used in the medical field since their launch in the 1970s. But so far, its ubiquitous deficiencies, defects and drawbacks are summed up as follows: 1. Cannot effectively control the aerodynamic size of suitable medicated pow...

Claims

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Application Information

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IPC IPC(8): A61M15/00
Inventor 于清
Owner 于清
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