Method for preparing chemical intermediates by using mixed o/m/p-cresol

Abstract

The invention provides a new method for preparing chemical intermediates by using mixed o / m / p-cresol. The method comprises the following steps of: taking mixed solution of o-cresol, m-cresol and p-cresol a raw material, performing alkylation on the mixed solution in the presence of an alkylating agent and a catalyst to obtain mixed solution of 6-tertbutyl-o-cresol, 6-tertbutyl-m-cresol and 2-tertbutyl-o-cresol, and rectifying the mixed solution to obtain high-purity chemical intermediate products of the 6-tertbutyl-o-cresol, the 6-tertbutyl-m-cresol and the 2-tertbutyl-o-cresol. The method has high reaction conversion rate, and can improve the utilization rate of atoms and reduce the raw material consumption and the production cost.

Description

technical field

[0001] The invention relates to a method for preparing chemical intermediates by using m-p-mixed cresols, specifically using a mixture of o-cresols, m-cresols and p-cresols to produce high-purity antioxidant intermediates 6-tert-butyl o-cresol, 6-tert-butyl-m-cresol and 2-tert-butyl-p-cresol methods. Background technique

[0002] 6-tert-butyl-o-cresol, 6-tert-butyl-m-cresol and 2-tert-butyl-p-cresol are important chemical intermediates. 6-tert-butyl-o-cresol is the main raw material for the preparation of asymmetric hindered phenolic antioxidants Irganox245, SumilizerGA / Mark AO-80, 736, etc.; 6-tert-butyl-m-cresol is mainly used in the production of 300, CA, BBM and other varieties 2-tert-butyl-p-cresol is an intermediate for synthesizing antioxidants 2246, 2246S, 264 and UV absorber UV326. The traditional production method of high-purity 6-tert-butyl-o-cresol, 6-tert-butyl-m-cresol and 2-tert-butyl-p-cresol is to use high-purity ortho-cresol, m-cresol and ...