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Clay-enhanced cuttlefish bone meal hemostatic gauze and manufacturing method thereof

A technology of squid bone powder and hemostatic gauze, which is applied in medical science, absorbent pads, bandages, etc., and can solve the problems of acute hemostasis medical devices that have not yet been seen

Inactive Publication Date: 2010-10-27
张胜民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no reports of cuttlefish bone powder being used in acute hemostatic medical devices such as hemostatic gauze

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A hemostatic gauze containing squid bone powder and kaolin, wherein the mass ratio of squid bone powder to kaolin is 7.5: 2.5, and the specific preparation method is as follows:

[0032] 1. Prepare a stable suspension slurry with water, cuttlefish bone powder and kaolin, and add polyvinyl alcohol (molecular weight 30,000 to 70,000) as a linking agent. In the slurry, the mass ratio of cuttlefish bone meal, kaolin and polyvinyl alcohol is 7.5:2.5:0.25, the particle size of cuttlefish bone meal is 10-100 μm, and the particle size of kaolin is about 100 μm;

[0033] 2. Heat the slurry to boiling, and soak the medical cotton cloth in the boiling slurry for 30 minutes;

[0034] 3. Take out the wet medical cotton cloth, dry it, and then roll it;

[0035] 4. Dry at high temperature at 80°C for 12 hours, and perform autoclaving and ultraviolet sterilization to obtain a clay-reinforced squid bone powder hemostatic gauze product.

Embodiment 2

[0037] A kind of hemostatic gauze containing squid bone powder, the specific preparation method is as follows:

[0038] 1. Prepare a stable suspension slurry with water and squid bone powder, and add glycerol (glycerin) as a linking agent. In the slurry, the mass ratio of the cuttlefish bone meal to glycerin is 100:3, and the particle size of the cuttlefish bone meal is 20-200 μm;

[0039] 2. Heat the slurry to 30°C, and soak the medical cotton cloth in the boiling slurry for 75 minutes;

[0040] 3. Take out the wet medical cotton cloth, dry it, and then roll it;

[0041] 4. Dry at high temperature at 80°C for 24 hours, and perform autoclaving and ultraviolet sterilization to obtain cuttlefish bone powder hemostatic gauze products.

Embodiment 3

[0043] A kind of hemostatic gauze containing squid bone meal, kaolin, and diatomaceous earth, the specific preparation method is as follows:

[0044] 1. Prepare a stable suspension slurry with water, squid bone meal, kaolin and diatomaceous earth, and add polyethylene glycol (molecular weight 4000) as a linking agent. In the slurry, the mass ratio of cuttlefish bone powder, kaolin, diatomite and polyethylene glycol is 8:1:1:0.4, the particle size of cuttlefish bone powder is 5-50 μm, the particle size of kaolin is 5-50 μm, and the diatomite The particle size is 5-50μm;

[0045] 2. Heat the slurry to 60°C, apply the slurry to one side of the medical non-woven fabric, and soak the entire medical non-woven fabric;

[0046] 3. Take out the wet medical cotton cloth, dry it, and then press it flat;

[0047] 4. Dry at high temperature at 80°C for 12 hours, and perform autoclaving and ultraviolet sterilization to obtain cuttlefish bone powder hemostatic gauze products.

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Abstract

The invention relates to clay-enhanced cuttlefish bone meal hemostatic gauze and a manufacturing method thereof. The hemostatic gauze comprises a substrate material, cuttlefish bone meal which is combined on the substrate material and is used as hemostat and clay which is combined on the substrate material and is used for enhancing the hemostatic effect, or also comprises other beneficial components which have the promoting effect on hemostasis and a connection agent for combining each component on the substrate material. The manufacturing method comprises the following steps of: preparing a suspension sizing agent by using water, the cuttlefish bone meal and the clay, and heating the suspension sizing agent at the temperature of 15 DEG C until the suspension sizing agent is boiling; immersing the substrate material into the sizing agent, or coating the sizing agent on the substrate material; taking the substrate material impregnated or coated with the sizing agent out, and performing flat pressing or rolling, or after taking the substrate material impregnated or coated with the sizing agent out, covering one side or both sides of the substrate material coating with the sizing agent by using medical cotton yarn or non-woven fabrics, and performing the flat pressing or the rolling again; and performing drying and sterilization to obtain the clay-enhanced cuttlefish bone meal hemostatic gauze. The gauze is used for treating surgical haemorrhage; and compared with the treatment of the ordinary gauze, the clay-enhanced cuttlefish bone meal hemostatic gauze has the advantages that: the hemostatic time of the hemostatic gauze is shortened by 35.9 to 66.5 percent; and the blood loss amount of the hemostatic gauze is reduced by 49.9 to 88.4 percent.

Description

field of invention [0001] The invention relates to a medical dressing and a production process thereof, in particular to a clay-reinforced squid bone meal hemostatic gauze and a production process thereof. Background technique [0002] Trauma bleeding, bleeding in operation, etc. are common symptoms in surgical treatment. Blood loss will reduce the fluid in the blood vessels and cause hypotension, which will reduce the oxygen supply of the body tissues and damage the body. Mass blood loss may even cause serious consequences such as hemorrhagic shock, directly endangering human life. Therefore, in trauma treatment, surgical operation and other occasions, hemostasis operation must be performed on the bleeding site at the first time. [0003] Common hemostatic methods cover the surface of the wound with cotton and bandage it with sterile gauze to fix the wound and achieve the purpose of hemostasis. However, for large-scale wounds, deep wounds, etc., which will cause more bloo...

Claims

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Application Information

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IPC IPC(8): A61L15/42A61L15/44A61L15/18A61L15/28A61L15/32A61L15/40
Inventor 高浩元张金枝
Owner 张胜民
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