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Method and device for pressure regulation and fixation of epidural microstimulation (EMS) visual cortex neural prosthesis

A fixation device, dura mater technology, applied in the direction of prosthesis, medical science, etc., can solve the problems of affecting recording/stimulating electrical signals, and the connection of implanted electrode chips is not firm, so as to reduce mechanical damage, ensure accuracy, reduce Effects of lead stress

Inactive Publication Date: 2012-07-04
CHONGQING UNIV
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Problems solved by technology

[0006] The applicant has found through long-term research that the connection between the implanted electrode chip and the implanted dura mater is not firm, and the mechanical pull of the implanted electrode chip will affect the recording / stimulation electrical signal

Method used

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  • Method and device for pressure regulation and fixation of epidural microstimulation (EMS) visual cortex neural prosthesis
  • Method and device for pressure regulation and fixation of epidural microstimulation (EMS) visual cortex neural prosthesis
  • Method and device for pressure regulation and fixation of epidural microstimulation (EMS) visual cortex neural prosthesis

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Embodiment Construction

[0019] like figure 1 and figure 2 As shown, the pressure regulating and fixing device of the epidural electrical stimulation cortical neural prosthesis is composed of a microelectrode array chip 2, an agar cover sheet 3, a pressure regulating plate 4 and a stereotaxic frame. In the figure, 1 is the skull outside the bone window in the visual cortex area, 5 is the subskull dura mater in the visual cortex area, 6 is the cerebrospinal fluid layer below the dura mater in the visual cortex area, 7 is the pia mater and cortex in the visual cortex area, and 8 is An adapter, one end of the adapter 8 is connected to the microelectrode array chip 2 through the lead 12, and the other end of the adapter is connected to the external nerve electrical stimulation signal generator / multi-channel physiological signal recorder through the lead 12. The microelectrode array chip 2 is used to realize the interface with the dura mater tissue above the visual cortex. On the one hand, it can transmi...

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Abstract

The invention relates to a method and a device for pressure regulation and fixation of an epidural microstimulation (EMS) visual cortex neural prosthesis. The device consists of a pressure regulation plate, pressure regulation screws and a three-dimensional locating rack, wherein the pressure regulation plate can realize an interface between a microelectrode array chip and endocranium in a bone window; the pressure between a microelectrode array chip and an implanted endocranium region can be finely regulated through the pressure regulation screws; and the horizontal distance of a support anda shift port is regulated by a beam of the three-dimensional locating rack to improve effective transfer of a neuroelectricity stimulation signal in the endocranium and other nervous tissues and effectiveness of signal record. The device can effectively fix the EMS visual cortex neural prosthesis and effectively regulate the pressure between the microelectrode array chip and the endocranium, thereby ensuring accuracy, reality and stability of a microelectrode array chip stimulation signal and voltage signal record.

Description

technical field [0001] The invention relates to a technique for pressure regulation and fixation of a cortical nerve prosthesis. Background technique [0002] Impaired nerve function will bring great pain to patients, and it is currently difficult to cure most of the nervous system injuries with biological methods. With the rapid development of microelectronics technology and related fields of neurobiology, a new interdisciplinary research field has emerged, that is, using the function of surviving neurons after damage to neural pathways, and implanting electrodes and functional integrated circuits to complete biological research. The function of information acquisition, processing and regeneration stimulation, so as to achieve the purpose of repairing and rebuilding the nervous system function. The ultimate goal of nerve function restoration is to develop a system-on-a-chip that is fully integrated or hybrid-integrated with nerve microelectrodes and function restoration in...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/02
Inventor 王星侯文生郑小林阴正勤姚军平郭冰冰石卫卫
Owner CHONGQING UNIV
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