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Gel for treating gynecologic inflammation and preparation method thereof

A technology of gynecological inflammation and Kangfu gel, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc., to achieve the effects of easy control of product quality, good stability, and simple production process

Inactive Publication Date: 2010-12-29
贵州健兴药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing Kangfu ointment preparations have a single variety, and the stability of product quality and the reliability of curative effect are all relatively poor and unfavorable for oral administration. It is inconvenient for patients to use and cannot fully meet the needs of the market.

Method used

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  • Gel for treating gynecologic inflammation and preparation method thereof
  • Gel for treating gynecologic inflammation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Example 1. The ingredients of Kangfu gel are as follows: 145g of Angelica dahurica, 145g of Fructus Cnidii, 145g of Zanthoxylum bungeanum, 30g of inulin, and 30g of borneol.

[0055] The gel formula is: 100g extract of raw material medicinal materials, 30g borneol, 0.3g disodium edetate, 30g carbomer, 500g propylene glycol, 120g ethanol, 10g azone, 1g ethylparaben, and the rest are Water, 1000g in total. During the preparation, take the four raw materials of Angelica dahurica, Cnidium, Zanthoxylum bungeanum, and Tumuxiang, add 10 times the amount of water to distill for 3.5 hours, collect the aromatic water and water decoction respectively; redistill the aromatic water for 30 minutes to obtain a rectified liquid. The above decoction was filtered, and the filtrate was concentrated to a relative density of 1.15-1.22 (25°C). Add ethanol to make the alcohol content 70%, let it stand still, take the supernatant and adjust the pH value to 8.0 with 10% sodium hydroxide solut...

Embodiment 2

[0056] Example 2. Composition of raw materials for Kangfu gel: 145g of Angelica dahurica, 145g of Cnidium chinensis, 145g of Zanthoxylum bungeanum, 30g of Tumuxiang, and 30g of borneol.

[0057] The gel formula is: 100g extract of raw material medicinal materials, 30g borneol, 0.3g disodium edetate, 30g carbomer, 500g propylene glycol, 120g ethanol, 10g azone, 1g ethylparaben, and the rest are Water, 1000g in total. During the preparation, take the four raw materials of Angelica dahurica, Cnidium, Zanthoxylum bungeanum, and Tumuxiang, add 8 times the amount of water to distill for 2 hours, and collect the aromatic water and water decoction respectively. The aromatic water was redistilled for 30 minutes to obtain a distillate. The water decoction is filtered, and the filtrate is concentrated to a relative density of 1.15-1.22 (25°C). Add ethanol to make the alcohol content 70%, let it stand still, take the supernatant and adjust the pH value to 8.0 with 10% sodium hydroxide ...

Embodiment 3

[0058] Example 3. Composition of raw materials for Kangfu gel: 145g of Angelica dahurica, 145g of Cnidium chinensis, 145g of Zanthoxylum bungeanum, 30g of Tumuxiang, and 30g of borneol.

[0059] The gel formula is: 100g extract of raw material medicinal materials, 30g borneol, 0.3g disodium edetate, 30g carbomer, 500g propylene glycol, 120g ethanol, 10g azone, 1g ethylparaben, and the rest are Water, 1000g in total. During the preparation, take the four raw materials of Angelica dahurica, Cnidium, Zanthoxylum bungeanum, and Tumuxiang, add 12 times the amount of water to distill for 4 hours, and collect the aromatic water and water decoction respectively. The aromatic water was redistilled for 90 minutes to obtain a distillate. The water decoction was filtered, and the filtrate was concentrated to a relative density of 1.15-1.22 (25°C). Add ethanol to make the alcohol content 70%, let it stand still, take the supernatant and adjust the pH value to 8.0 with 10% sodium hydroxi...

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Abstract

The invention discloses Kangfu gel for treating gynecologic inflammation and a preparation method thereof. The gel is prepared from extract extracted from angelica dahurica, common cnidium fruit, wild pepper and elecampane inula root serving as medicinal raw materials, borneol, auxiliary materials and an appropriate amount of water. The Kangfu gel is a new Chinese medicinal formulation for treating the gynecologic inflammation and is an improved formulation of the conventional Kangfu ointment. The conventional Kangfu ointment is prepared into external gel, so that formulation varieties are enriched to meet different demands of different patients, curative effect is enhanced, response is quick, tract administration is facilitated and the gel is convenient to use. The method has the advantages of simple and convenient production process, convenient control of product quality, high stability and high safety. A prepared gel preparation is convenient to use and has the remarkable effect of treating the gynecologic inflammation.

Description

technical field [0001] The invention relates to an externally-used traditional Chinese medicine preparation for treating gynecological inflammation and a preparation method thereof, in particular to a Kangfu gel preparation for treating gynecological inflammation and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Kangfu ointment is a traditional Chinese medicine preparation widely used clinically to treat gynecological inflammation. It is mainly used for vulvar or vaginal congestion, swelling, burning, pain, increased secretions or local ulcers and erosions caused by vulvitis, vulvar ulcers, and vaginitis. , itching, etc., has a good therapeutic effect. However, the existing Kangfu ointment preparations have a single variety, and the stability of the product quality and the reliability of the curative effect are relatively poor, and it is not conducive to oral drug administration, which is inconvenient for patients...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K9/00A61K47/32A61P15/00A61P15/02A61K31/045
Inventor 孙平
Owner 贵州健兴药业有限公司
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